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COMPLETED Phase 2

A Study to Measure the Effects of Using Tradipitant on Nausea and Vomiting After GLP-1R Agonist Use

NCT06804603 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this study is to measure the effects of using Tradipitant after GLP-1R agonist use on nausea and vomiting in healthy overweight, class I, or class II obese volunteers. The study is placebo-controlled with two treatment arms.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Tradipitant

Study Locations (3)

California

  • Vanda Investigational Site — Los Angeles

Minnesota

  • Vanda Investigational Site — Rochester

New York

  • Vanda Investigational Site — New York

Trial Details

FieldValue
Enrollment Target 124 participants
Start Date 2025-02-25
Est. Completion 2025-10-06
Phase Phase 2

Sponsor

Vanda Pharmaceuticals

34 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06804603

The ClinicalTrials.gov registry entry for NCT06804603 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 124 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanda Pharmaceuticals, which has 34 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06804603 reports 3 study locations spanning 3 distinct geographic areas — top geographies include California, Minnesota, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06804603 about?

NCT06804603 is a clinical study titled "A Study to Measure the Effects of Using Tradipitant on Nausea and Vomiting After GLP-1R Agonist Use". The goal of this study is to measure the effects of using Tradipitant after GLP-1R agonist use on nausea and vomiting in healthy overweight, class I, or class II obese volunteers. The study is placebo-controlled with two treatment arms.

What is the current status of trial NCT06804603?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 124 participants. The study started on 2025-02-25. Estimated completion is 2025-10-06.

What conditions does trial NCT06804603 study?

This clinical trial studies the following conditions: Obesity. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06804603?

The interventions under investigation include: Placebo (DRUG), Tradipitant (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06804603?

This trial is sponsored by Vanda Pharmaceuticals, which has 34 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06804603 being conducted?

This trial has 3 study locations across California, Minnesota, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial