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NCT01158573 · ClinicalTrials.gov registry record

Role of Cysteinyl Leukotrienes in the Pathogenesis of Asthma in Obesity

A clinical trial of Obesity and Asthma, sponsored by University of Michigan.

Completed
Registry status
117
Enrollment target
1
Study location

NCT01158573 is a study of Obesity and Asthma that has completed, run by University of Michigan. The registered enrollment target is 117 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01158573, a study of Obesity and Asthma, has completed, sponsored by University of Michigan.

COMPLETED
Registry status
117 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to examine whether there are higher levels of cysteinyl leukotrienes in obese subjects than in non-obese subjects. Cysteinyl leukotrienes are pro-inflammatory substances that cause asthma by narrowing the airways of the lung. The investigators want to see if subjects with increased fat stores and therefore increased leptin, which is a fat-related protein that regulates leukotrienes, have increased levels of leukotrienes in the blood, lung and urine. The investigators would also like to determine the relationship between cysteinyl leukotrienes and exhaled nitric oxide levels in asthmatics with and without obesity. Nitric oxide is anti-inflammatory and suppresses leukotriene synthesis.

Conditions Studied

Study Locations (1)

Michigan

  • University of Michigan - Ann Arbor

Trial Details

FieldValue
Enrollment Target 117 participants
Start Date 2010-07
Est. Completion 2013-05

Sponsor

University of Michigan

1,327 total trials

What the Registry Record Tells You About NCT01158573

The ClinicalTrials.gov registry entry for NCT01158573 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 117 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (86% lower). The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 0 interventions.

NCT01158573 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT01158573 about?

NCT01158573 is a clinical study titled "Role of Cysteinyl Leukotrienes in the Pathogenesis of Asthma in Obesity". The purpose of this study is to examine whether there are higher levels of cysteinyl leukotrienes in obese subjects than in non-obese subjects. Cysteinyl leukotrienes are pro-inflammatory substances that cause asthma by narrowing the airways of the lung. The investigators want to see if subjects wit...

What is the current status of trial NCT01158573?

This trial is currently completed. The enrollment target is 117 participants. The study started on 2010-07. Estimated completion is 2013-05.

What conditions does trial NCT01158573 study?

This clinical trial studies the following conditions: Obesity, Asthma.

Who is sponsoring clinical trial NCT01158573?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01158573 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.