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NCT01158573 · ClinicalTrials.gov registry record
Role of Cysteinyl Leukotrienes in the Pathogenesis of Asthma in Obesity
A clinical trial of Obesity and Asthma, sponsored by University of Michigan.
- Completed
- Registry status
- 117
- Enrollment target
- 1
- Study location
NCT01158573: Completed study of Obesity and Asthma, sponsored by University of Michigan.
NCT01158573 is a study of Obesity and Asthma that has completed, run by University of Michigan. The registered enrollment target is 117 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01158573, a study of Obesity and Asthma, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- 117 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to examine whether there are higher levels of cysteinyl leukotrienes in obese subjects than in non-obese subjects. Cysteinyl leukotrienes are pro-inflammatory substances that cause asthma by narrowing the airways of the lung. The investigators want to see if subjects with increased fat stores and therefore increased leptin, which is a fat-related protein that regulates leukotrienes, have increased levels of leukotrienes in the blood, lung and urine. The investigators would also like to determine the relationship between cysteinyl leukotrienes and exhaled nitric oxide levels in asthmatics with and without obesity. Nitric oxide is anti-inflammatory and suppresses leukotriene synthesis.
Primary Outcome
Measurement of plasma leptin in obese and non obese asthmatics and non-asthmatic subjects from a single blood draw.
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 117 participants |
| Start Date | 2010-07 |
| Est. Completion | 2013-05 |
What the finished NCT01158573 record still lists
NCT01158573 is an observational study that tracks outcomes without assigning an intervention. The registered 117 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (86% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 0 interventions.
NCT01158573 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT01158573 about?
NCT01158573 is a clinical study titled "Role of Cysteinyl Leukotrienes in the Pathogenesis of Asthma in Obesity". The purpose of this study is to examine whether there are higher levels of cysteinyl leukotrienes in obese subjects than in non-obese subjects. Cysteinyl leukotrienes are pro-inflammatory substances that cause asthma by narrowing the airways of the lung. The investigators want to see if subjects wit...
What is the current status of trial NCT01158573?
This trial is currently completed. The enrollment target is 117 participants. The study started on 2010-07. Estimated completion is 2013-05.
What conditions does trial NCT01158573 study?
This clinical trial studies the following conditions: Obesity, Asthma.
Who is sponsoring clinical trial NCT01158573?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01158573 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01158573's enrollment target sits among peer trials
117 449th of 1053 higher than 605 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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