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NCT04311411 · ClinicalTrials.gov registry record · Phase 1
A Study of Tirzepatide in Overweight and Very Overweight Participants
A Phase 1 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 1
- Development phase
- 114
- Enrollment target
- 3
- Study locations
NCT04311411: Completed Phase 1 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
NCT04311411 is a Phase 1 study of Obesity and Overweight that has completed, run by Eli Lilly and Company. The registered enrollment target is 114 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (86% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04311411, a Phase 1 study of Obesity and Overweight, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 114 participants
- Enrollment target
- 3
- Study locations
Study Summary
The main purpose of this study is to measure the effect of tirzepatide on food intake in participants who are overweight or very overweight. The study will also use imaging to learn more about how tirzepatide affects specific parts of the brain. The effect of tirzepatide on appetite will also be studied. The study will last up to about four months and will include up to 14 visits to the study center.
Primary Outcome
Change from baseline in calorie intake in participants receiving tirzepatide or placebo at week 3 is reported.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Tirzepatide
- DRUG Liraglutide
Study Locations (3)
Indiana
- Indiana University School of Medicine - Indianapolis
Louisiana
- Pennington Biomedical Research Center - Baton Rouge
Maryland
- Johns Hopkins University School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 114 participants |
| Start Date | 2020-08-24 |
| Est. Completion | 2022-12-16 |
| Phase | Phase 1 |
What the finished NCT04311411 record still lists
NCT04311411 is an interventional study that assigns participants to a tested intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (86% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT04311411 reports a single indexed study location in Indiana, Louisiana, Maryland.
Frequently Asked Questions
What is clinical trial NCT04311411 about?
NCT04311411 is a clinical study titled "A Study of Tirzepatide in Overweight and Very Overweight Participants". The main purpose of this study is to measure the effect of tirzepatide on food intake in participants who are overweight or very overweight. The study will also use imaging to learn more about how tirzepatide affects specific parts of the brain. The effect of tirzepatide on appetite will also be stu...
What is the current status of trial NCT04311411?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 114 participants. The study started on 2020-08-24. Estimated completion is 2022-12-16.
What conditions does trial NCT04311411 study?
This clinical trial studies the following conditions: Obesity, Overweight.
What interventions are being tested in trial NCT04311411?
The interventions under investigation include: Placebo (DRUG), Tirzepatide (DRUG), Liraglutide (DRUG).
Who is sponsoring clinical trial NCT04311411?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04311411 being conducted?
This trial has 3 study locations across Indiana, Louisiana, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04311411's enrollment target sits among peer trials
114 453rd of 1053 higher than 599 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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