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Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,963 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,963 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Open enrollment, early-phase tilt
Obesity has 1,057 registered US clinical trials, 306 of them open to new participants right now, about 29% of the total.
- 306
- recruiting participants now
- 29%
- of trials open to enrollment
- 107
- in Phase 3-4 (later-stage)
- 48
- top sponsor: Eli Lilly and Company
Corpus placement: #3 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
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Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
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Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 15 of 22
Reinforcement of Surgical Staple Lines Using Peri-Strips Dry (PSD) With Veritas Collagen Matrix
Baxter Healthcare Corporation
NCT00566943
Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball
Pacira Pharmaceuticals
NCT02142829
Enhanced Internet Behavior Therapy for Treating Obesity
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00212238
Long Term Free Living Study With Modified Foods and Type 2 Diabetics
Johns Hopkins Bloomberg School of Public Health
NCT00198913
Exercise Intolerance in Elderly Patients With Diastolic Heart Failure
Wake Forest University
NCT00959660
Obesity in G60 Trauma Patients / Obesity in G60 Trauma Patients
Methodist Health System
NCT04640701
Effects of Advertising on Young Children's Perception of Taste
Stanford University
NCT00185536
Predicting Adherence to a Heart-Healthy Diet in Lean and Obese Individuals
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01862796
The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00072917
A Research Study on How a Dose of NNC0662-0419 Works in Japanese, Chinese and Non-Asian Participants Living With Overweight or Obesity
Novo Nordisk A/S
NCT07101783
PATH to Health: An Exploration of Digital Behavioral Weight Loss Approaches
University of North Carolina, Chapel Hill
NCT05929469
Balanced (Egg) Protein During Obesity Reduction: Differential Responses of Insulin Resistance by Race
Duke University
NCT03771261
The Collateral Impact of Bariatric Surgery on Families
Geisinger Clinic
NCT02021630
Lifestyle Changes Through Exercise and Nutrition
Pennington Biomedical Research Center
NCT02863887
Reducing Antipsychotic-Induced Weight Gain in Children With Metformin
Nationwide Children's Hospital
NCT01231074
A Study of LY3841136 in Overweight and Obese Participants
Eli Lilly and Company
NCT06345066
Assisted Exercise in Obese Endometrial Cancer Patients
Case Comprehensive Cancer Center
NCT01870947
Eating Behaviors Among Weight-Discordant Siblings
University of Pennsylvania
NCT01598389
A First Human Dose Trial Investigating Safety, Tolerability and Pharmacokinetics for Single Doses and Multiple Doses of NNC0165-1562 in Overweight to Obese But Otherwise Healthy Subjects
Novo Nordisk A/S
NCT02568306
The Sweet PEA Study: Effects of Diet During Pregnancy on Infant Growth and Development.
University of Southern California
NCT04674033
Examination of a Treatment Program for Overweight Children, Adolescents, and Their Families
University of Kansas
NCT00365807
Puberty Related Intervention to Improve Metabolic Outcomes (The PRIMO Study)
University of Alabama at Birmingham
NCT01410643
Weight Watchers Online 2015
The Miriam Hospital
NCT02417220
"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"
University of Wisconsin, Madison
NCT01317329
Taste Perception and Chronic Disease Risk
Tufts University
NCT01023906
Weight Loss in Adults Over 50 with Obesity
University of Alabama at Birmingham
NCT04014296
Exercise Genes: Genomic Association With Exercise Reinforcement
USDA Grand Forks Human Nutrition Research Center
NCT02416882
Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes
Joslin Diabetes Center
NCT01073020
"Generation Fit and Exerlearning With In the Groove"
MaineHealth
NCT00424918
A School Nurse-Delivered Intervention for Overweight and At Risk Adolescents
University of Massachusetts, Worcester
NCT00682188
Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of NO-13065 in Healthy and Obese Adult Subjects
Otsuka Pharmaceutical Factory
NCT04838639
Families Becoming Healthy Together
The University of Tennessee, Knoxville
NCT04027426
Study of Coffee Mannooligosaccharides for Weight Management
Mondelēz International
NCT00932750
A Study to Learn How the Study Medicine Danuglipron is Taken Up Into the Blood and If Danuglipron Changes How the Body Processes Other Study Medicines (Atorvastatin and Rosuvastatin) in Healthy Adults Who Are Overweight or Obese
Pfizer
NCT06567327
An Enhanced Protein (Dairy) Weight Loss Intervention for Dynapenic Obesity: Impact on Muscle Quality and Composition
Duke University
NCT02437643
Efficacy of Parent-Child Dieting Plans Incorporating Medifast Meal Replacements for Weight Loss
Johns Hopkins Bloomberg School of Public Health
NCT00198744
Improving Metabolic Health in Patients With Diastolic Dysfunction
University of Texas Southwestern Medical Center
NCT03448185
Evaluation of a Health at Every Size vs a Behavioral Weight Loss Approach for Obese Women
The Reading Hospital and Medical Center
NCT00769717
Applying Social Comparison Theory to Behavioral Weight Loss: Does Modifying Group Membership Improve Outcome?
The Miriam Hospital
NCT00716027
A Weight Loss Trial for Emotional Eating
Temple University
NCT02055391
Insulin and the Polycystic Ovary Syndrome--Weight Reduction Study
Virginia Commonwealth University
NCT00436865
Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate
Pennington Biomedical Research Center
NCT00999297
In-home Obesity Prevention to Reach Low-income Infants
University of Southern California
NCT03529695
An Interactive Web-based Intervention to Achieve Healthy Weight in Young Children
University of Wisconsin, Madison
NCT01552642
Phone Coaching for Weight Loss Maintenance
The Miriam Hospital
NCT04293055
Physical Activity Referrals to the Community
University of California, Berkeley
NCT02044744
Gamification and Energetic Behavior Changes
Children's Hospital of Philadelphia
NCT03050840
Nutrition Outreach and Understanding: Research In Serving Hearts Through Healthy Eating And Tailored Support
Amanda Shallcross
NCT06460272
The Optimum Time for Preoxygenation Based on Body Mass Index
Cedars-Sinai Medical Center
NCT01114932
Feasibility of Integrating Indirect Calorimetry (IC) Technology in Primary Care
Colorado Center for Chronic Care Innovations
NCT00750022
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Obesity right now
306 recruiting of 1,057 indexed (29% open).
Phase mix: 107 late (III/IV) vs 196 early (I/II) (early-phase heavy).
Top sponsor: Eli Lilly and Company (48 trials), 9 others listed. 50 shown below, recruiting first. #3 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Obesity?
PlainTrial tracks 1,057 US clinical trials for Obesity, of which 306 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Obesity?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.