Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 306 recruiting now early-phase tilt #3 of 28,963 conditions

Obesity: early-phase trial registry

306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #3 of 28,963 conditions by registered trial count.

1,057 US clinical trials · 306 currently recruiting · #3 of 28,963 conditions by registered trial count

Obesity: 1,057 US clinical trials tracked, 306 recruiting.

Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.

Open enrollment, early-phase tilt

Obesity has 1,057 registered US clinical trials, 306 of them open to new participants right now, about 29% of the total.

306
recruiting participants now
29%
of trials open to enrollment
107
in Phase 3-4 (later-stage)
48
top sponsor: Eli Lilly and Company

Corpus placement: #3 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Obesity is recruiting below its size-band peers.

    306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Obesity trials is spread across many organizations.

    Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.

  3. Typical Obesity enrolment sits around 90 participants.

    Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.

  4. Obesity research is mostly interventional.

    894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 195Phase 2101Phase 369Phase 438

Open and recent trials

1,057 total, page 13 of 22

COMPLETED NA 225 participants

Vitamin D and Vascular Health in Children

University of Pittsburgh

NCT01797302

COMPLETED NA 223 participants

Take HEED (Healthy Eating and Exercise Decisions)

Kaiser Permanente

NCT00306709

COMPLETED NA 222 participants

Maintenance After Initiation of Nutrition TrAINing

VA Office of Research and Development

NCT01357551

COMPLETED 221 participants

The Effects of Natural Sugars in Breast Milk on Healthy Infant Growth and Development

University of Southern California

NCT04434027

COMPLETED Phase 3 218 participants

A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight

Boehringer Ingelheim

NCT06309992

COMPLETED Phase 2 215 participants

Examining the Feasibility of Collaborative Care Treatment for Overweight Adolescents

Kaiser Permanente

NCT00462267

COMPLETED NA 213 participants

Family Exergaming: A Research Study Testing a Videogame Intervention to Increase Physical Activity for Families

MaineHealth

NCT00889122

COMPLETED NA 212 participants

Lottery Incentives for Moving

Harvard University

NCT01278654

COMPLETED NA 211 participants

REAL HEALTH-Diabetes: Reach Ahead for Lifestyle and Health-Diabetes

Massachusetts General Hospital

NCT02320253

COMPLETED NA 207 participants

A Community-based Study to Target Childhood Obesity

Boston University

NCT02890056

COMPLETED Phase 2 207 participants

Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos

Stanford University

NCT01242683

COMPLETED NA 205 participants

A Mail and Video-based Weight Loss Trial in Breast Cancer Survivors

Yale University

NCT02681965

COMPLETED NA 202 participants

Multi-site Trial Using SMS to Improve Infant Weight

University of Puerto Ri

NCT02903186

COMPLETED NA 200 participants

Video Games for Obesity and Diabetes Prevention-Diab & Nano

Baylor College of Medicine

NCT01846377

COMPLETED NA 200 participants

Increasing Treatment for Obesity Among Underserved Populations

University of Utah

NCT05666323

COMPLETED NA 196 participants

Eating Peanuts for Health

Purdue University

NCT01886326

COMPLETED NA 195 participants

Research Intervention to Support Healthy Eating and Exercise

University of Connecticut

NCT04353258

COMPLETED NA 195 participants

Raising Well at Home

Washington University School of Medicine

NCT04224623

COMPLETED NA 194 participants

Strong Hearts: Rural CVD Prevention

Cornell University

NCT02499731

COMPLETED NA 191 participants

Financial Incentives for Maintenance of Weight Loss

University of Pennsylvania

NCT01900392

COMPLETED NA 190 participants

Using Novel Behavioral Approaches to Improve Long-Term Weight Loss Outcomes

The Miriam Hospital

NCT02156752

COMPLETED NA 187 participants

Weight Management in Rural Communities

University of Kansas

NCT02932748

COMPLETED NA 186 participants

Walking For Wellness Program Evaluation

University of Pennsylvania

NCT00156351

COMPLETED NA 182 participants

A Web-based Approach to Treating Cardiovascular Disease Risk in Employees With Metabolic Syndrome

Baptist Health South Florida

NCT01912209

COMPLETED NA 180 participants

Diet and Exercise for Underserved Women

University of South Carolina

NCT01172340

COMPLETED NA 180 participants

Potato Consumption and Energy Balance

University of Alabama at Birmingham

NCT03518515

COMPLETED Phase 4 180 participants

Misoprostol Dosing in BMI Greater Than 30

University of Texas at Austin

NCT05262738

COMPLETED Phase 2 179 participants

A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight

Eli Lilly and Company

NCT06124807

COMPLETED NA 176 participants

Spark: Finding the Optimal Tracking Strategy for Weight Loss in a Digital Health Intervention

Stanford University

NCT05249465

COMPLETED NA 176 participants

Whole Body Vibration Training for Healthy Body Composition in Young Adults

Oregon Health and Science University

NCT02134275

COMPLETED Phase 1 174 participants

A Mentor-Based Approach to Long-Term Weight Loss

University of Pittsburgh

NCT00177697

COMPLETED NA 174 participants

Environmental Strategies & Behavior Change to Reduce Overeating in Obese Children

Stanford University

NCT01221220

COMPLETED NA 171 participants

Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study

Aspire Bariatrics

NCT01766037

COMPLETED 166 participants

Regional Fat Depots and Insulin Resistance

Stanford University

NCT01336777

COMPLETED 165 participants

Assessment of Outcomes Following Bariatric Surgery for Mississippi State Employees

University of Mississippi Medical Center

NCT01162668

COMPLETED NA 160 participants

Neurobehavioral Plasticity to Regular Sugar-Sweetened Beverage Intake: An fMRI Experiment

University of North Carolina, Chapel Hill

NCT03490734

COMPLETED Phase 2 160 participants

Sandostatin LAR® Depot in Patients With Primary Insulin Hypersecretion (PIH) and at Least Moderate Obesity

Novartis

NCT00094146

COMPLETED 157 participants

Lorcaserin: Real World Experience in an Insurance-Based Weight Management Clinic

Scripps Whittier Diabetes Institute

NCT03552107

COMPLETED NA 157 participants

Getting in Balance: A Workplace Diabetes Prevention Intervention Trial

Kaiser Permanente

NCT02589873

COMPLETED Phase 3 156 participants

Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes

US Department of Veterans Affairs

NCT00108459

COMPLETED Phase 2 152 participants

Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT05017571

COMPLETED Phase 2 151 participants

A 12-week Titrate Study TO Evaluate Safety, Tolerability AND Pharmacodynamics OF PF-06882961 IN Adults With Type 2 Diabetes Mellitus AND IN Non-diabetic Adults With Obesity

Pfizer

NCT04617275

COMPLETED Phase 4 150 participants

Lifestyle Modification and Liraglutide

University of Pennsylvania

NCT02911818

COMPLETED NA 150 participants

Advanced Medical Therapy Versus Advanced Medical Therapy Plus Bariatric Surgery for the Resolution of Type 2 Diabetes

The Cleveland Clinic

NCT00432809

COMPLETED 150 participants

Effects of Weight Loss on Cardio-respiratory Function

NYU Langone Health

NCT01410487

COMPLETED NA 149 participants

Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors-Renewal

Temple University

NCT03186508

COMPLETED NA 149 participants

Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians

Black Hills Center for American Indian Health

NCT00608387

COMPLETED NA 148 participants

Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia

University of Pittsburgh

NCT03749746

COMPLETED NA 147 participants

Lifestyle Intervention's Impact on Health Care Costs

University of Virginia

NCT00717158

COMPLETED NA 146 participants

Radio Stories About Children's Healthy Eating and Exercise

University of Minnesota

NCT02139787

← Previous Page 13 of 22 Next →

Phase Distribution

PhaseTrial count
Phase 1 95
Phase 2 101
Phase 3 69
Phase 4 38

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Obesity right now

306 recruiting of 1,057 indexed (29% open).

Phase mix: 107 late (III/IV) vs 196 early (I/II) (early-phase heavy).

Top sponsor: Eli Lilly and Company (48 trials), 9 others listed. 50 shown below, recruiting first. #3 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Obesity?

PlainTrial tracks 1,057 US clinical trials for Obesity, of which 306 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Obesity?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.