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Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,707 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,707 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Enrollment posture brief
Registry condition obesity
OPEN 306 | RECR 29% | LATE 107 | EARLY 196 | RANK #3 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Metastatic Pancreatic Adenocarcinoma (29% recruiting · 38 trials)
Obesity lists 306 open slots (29% of 1,057 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
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Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
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Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 13 of 22
Vitamin D and Vascular Health in Children
University of Pittsburgh
NCT01797302
Take HEED (Healthy Eating and Exercise Decisions)
Kaiser Permanente
NCT00306709
Maintenance After Initiation of Nutrition TrAINing
VA Office of Research and Development
NCT01357551
The Effects of Natural Sugars in Breast Milk on Healthy Infant Growth and Development
University of Southern California
NCT04434027
A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight
Boehringer Ingelheim
NCT06309992
Examining the Feasibility of Collaborative Care Treatment for Overweight Adolescents
Kaiser Permanente
NCT00462267
Family Exergaming: A Research Study Testing a Videogame Intervention to Increase Physical Activity for Families
MaineHealth
NCT00889122
Lottery Incentives for Moving
Harvard University
NCT01278654
REAL HEALTH-Diabetes: Reach Ahead for Lifestyle and Health-Diabetes
Massachusetts General Hospital
NCT02320253
A Community-based Study to Target Childhood Obesity
Boston University
NCT02890056
Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos
Stanford University
NCT01242683
A Mail and Video-based Weight Loss Trial in Breast Cancer Survivors
Yale University
NCT02681965
Multi-site Trial Using SMS to Improve Infant Weight
University of Puerto Ri
NCT02903186
Video Games for Obesity and Diabetes Prevention-Diab & Nano
Baylor College of Medicine
NCT01846377
Increasing Treatment for Obesity Among Underserved Populations
University of Utah
NCT05666323
Eating Peanuts for Health
Purdue University
NCT01886326
Research Intervention to Support Healthy Eating and Exercise
University of Connecticut
NCT04353258
Raising Well at Home
Washington University School of Medicine
NCT04224623
Strong Hearts: Rural CVD Prevention
Cornell University
NCT02499731
Financial Incentives for Maintenance of Weight Loss
University of Pennsylvania
NCT01900392
Using Novel Behavioral Approaches to Improve Long-Term Weight Loss Outcomes
The Miriam Hospital
NCT02156752
Weight Management in Rural Communities
University of Kansas
NCT02932748
Walking For Wellness Program Evaluation
University of Pennsylvania
NCT00156351
A Web-based Approach to Treating Cardiovascular Disease Risk in Employees With Metabolic Syndrome
Baptist Health South Florida
NCT01912209
Diet and Exercise for Underserved Women
University of South Carolina
NCT01172340
Potato Consumption and Energy Balance
University of Alabama at Birmingham
NCT03518515
Misoprostol Dosing in BMI Greater Than 30
University of Texas at Austin
NCT05262738
A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
Eli Lilly and Company
NCT06124807
Spark: Finding the Optimal Tracking Strategy for Weight Loss in a Digital Health Intervention
Stanford University
NCT05249465
Whole Body Vibration Training for Healthy Body Composition in Young Adults
Oregon Health and Science University
NCT02134275
A Mentor-Based Approach to Long-Term Weight Loss
University of Pittsburgh
NCT00177697
Environmental Strategies & Behavior Change to Reduce Overeating in Obese Children
Stanford University
NCT01221220
Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study
Aspire Bariatrics
NCT01766037
Regional Fat Depots and Insulin Resistance
Stanford University
NCT01336777
Assessment of Outcomes Following Bariatric Surgery for Mississippi State Employees
University of Mississippi Medical Center
NCT01162668
Neurobehavioral Plasticity to Regular Sugar-Sweetened Beverage Intake: An fMRI Experiment
University of North Carolina, Chapel Hill
NCT03490734
Sandostatin LAR® Depot in Patients With Primary Insulin Hypersecretion (PIH) and at Least Moderate Obesity
Novartis
NCT00094146
Lorcaserin: Real World Experience in an Insurance-Based Weight Management Clinic
Scripps Whittier Diabetes Institute
NCT03552107
Getting in Balance: A Workplace Diabetes Prevention Intervention Trial
Kaiser Permanente
NCT02589873
Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes
US Department of Veterans Affairs
NCT00108459
Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT05017571
A 12-week Titrate Study TO Evaluate Safety, Tolerability AND Pharmacodynamics OF PF-06882961 IN Adults With Type 2 Diabetes Mellitus AND IN Non-diabetic Adults With Obesity
Pfizer
NCT04617275
Lifestyle Modification and Liraglutide
University of Pennsylvania
NCT02911818
Advanced Medical Therapy Versus Advanced Medical Therapy Plus Bariatric Surgery for the Resolution of Type 2 Diabetes
The Cleveland Clinic
NCT00432809
Effects of Weight Loss on Cardio-respiratory Function
NYU Langone Health
NCT01410487
Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors-Renewal
Temple University
NCT03186508
Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians
Black Hills Center for American Indian Health
NCT00608387
Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia
University of Pittsburgh
NCT03749746
Lifestyle Intervention's Impact on Health Care Costs
University of Virginia
NCT00717158
Radio Stories About Children's Healthy Eating and Exercise
University of Minnesota
NCT02139787
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obesity page
1,057 registered trials, 306 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 306 Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Obesity trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity condition card totals 1,057 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.