Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 1

A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors

NCT02222922 · View on ClinicalTrials.gov ↗

Study Summary

To assess the safety and tolerability at increasing dose levels of PF-06647020 in patients with advanced solid tumors in order to determine the maximum tolerated dose and select the recommended Phase 2 dose.

Conditions Studied

Interventions

  • DRUG fluconazole
  • DRUG PF-06647020 Q3W
  • DRUG PF-06647020 Q2W
  • DRUG PF-06647020 combined with Avelumab

Study Locations (17)

Virginia

  • Inova Fairfax Hospital Woodburn GYN Infusion Center — Annandale
  • Mid Atlantic Gynecologic Oncology and Pelvic Surgery Associates (MAGOPSA) — Annandale
  • Fairfax Radiological Consultants — Fairfax
  • Inova Schar Cancer Institute — Fairfax
  • Inova Loudon Hospital — Leesburg

California

  • University of California Davis Comprehensive Cancer Center — Sacramento
  • University of California Davis Medical Center — Sacramento
  • Stanford Cancer Center — Stanford
  • Stanford Hospital and Clinics — Stanford

Alabama

  • University of Alabama at Birmingham — Birmingham
  • University of Alabama at Birmingham — Birmingham

Other

  • Hospital Universitario Fundacion Jimenez Diaz — Madrid
  • Hospital Universitario Madrid Sanchinarro — Madrid

Arizona

  • Scottsdale Healthcare Hospitals DBA HonorHealth — Scottsdale

Illinois

  • University of Chicago Medicine — Chicago

Michigan

  • START Midwest — Grand Rapids

Texas

  • South Texas Accelerated Research Therapeutics, LLC — San Antonio

Trial Details

FieldValue
Enrollment Target 138 participants
Start Date 2014-10-17
Est. Completion 2019-11-05
Phase Phase 1

Sponsor

Pfizer

769 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02222922

The ClinicalTrials.gov registry entry for NCT02222922 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 138 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 769 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Neoplasms appearing as the primary indexed condition, and to 4 interventions — of which fluconazole is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02222922 reports 17 study locations spanning 8 distinct geographic areas — top geographies include Virginia, California, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02222922 about?

NCT02222922 is a clinical study titled "A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors". To assess the safety and tolerability at increasing dose levels of PF-06647020 in patients with advanced solid tumors in order to determine the maximum tolerated dose and select the recommended Phase 2 dose.

What is the current status of trial NCT02222922?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 138 participants. The study started on 2014-10-17. Estimated completion is 2019-11-05.

What conditions does trial NCT02222922 study?

This clinical trial studies the following conditions: Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02222922?

The interventions under investigation include: fluconazole (DRUG), PF-06647020 Q3W (DRUG), PF-06647020 Q2W (DRUG), PF-06647020 combined with Avelumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02222922?

This trial is sponsored by Pfizer, which has 769 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02222922 being conducted?

This trial has 17 study locations across Alabama, Arizona, California, Illinois, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial