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ClinicalTrials.gov 50 recruiting now early-phase tilt #68 of 28,707 conditions

Neoplasms: early-phase trial registry

50 of 160 indexed Neoplasms trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #68 of 28,707 conditions by registered trial count.

160 US clinical trials · 50 currently recruiting · #68 of 28,707 conditions by registered trial count

Neoplasms: 160 US clinical trials tracked, 50 recruiting.

Neoplasms is the subject of 160 registered US clinical trials on ClinicalTrials.gov, 50 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 99 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 15 of these trials.

Enrollment posture brief

Registry condition neoplasms

OPEN 50 | RECR 31% | LATE 9 | EARLY 99 | RANK #68 | SPON 15

Nearest open-share peer: Aortic Valve Disease (31% recruiting · 16 trials)

Gastric Cancer45.3%Neoplasms (this)31%Parkinson's Disease26.1%Bipolar Disorder22.7%Influenza17.2%
Open-enrollment share among volume-matched conditions near Neoplasms

Neoplasms lists 50 open slots (31% of 160 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Neoplasms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Neoplasms is recruiting below its size-band peers.

    50 of 160 indexed trials (31.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Neoplasms trials is spread across many organizations.

    National Cancer Institute (NCI) accounts for 15 of 160 trials (9.4%). 85 distinct sponsors appear on at least one study for this condition label.

  3. Typical Neoplasms enrolment sits around 81 participants.

    Median target enrolment is 81 among the 159 trials that report a genuine target (sentinel values excluded). 87 of those (54.7%) plan for fewer than 100 participants.

  4. Neoplasms research is mostly interventional.

    130 interventional and 30 observational studies make up this index (81.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 181Phase 218Phase 37Phase 42

Open and recent trials

160 total, page 3 of 4

COMPLETED 120 participants

Genetic Exploration of the Molecular Basis of Malignancy in Adults

Sanford Health

NCT02416518

COMPLETED 119 participants

Biomarkers For Immune Checkpoint Inhibitors

Rhode Island Hospital

NCT04204434

COMPLETED Phase 1 102 participants

Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor

Pfizer

NCT00454649

COMPLETED Phase 1 79 participants

Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors

Novartis Pharmaceuticals

NCT02077933

COMPLETED Phase 1 79 participants

Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in Patients

Bayer

NCT01915576

COMPLETED 74 participants

Collection of Blood, Bone Marrow, Tumor or Tissue Samples

National Cancer Institute (NCI)

NCT00043615

COMPLETED Phase 1 74 participants

A Study Of Oral Palbociclib (PD-0332991), A Cyclin-Dependent Kinase Inhibitor, In Patients With Advanced Cancer

Pfizer

NCT00141297

COMPLETED NA 72 participants

Physical Activity and Healthy Eating Among Young Adult Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT05887401

COMPLETED 70 participants

An Exploratory Study of the Use of Five Wishes as a Tool for Advanced Care Planning in Young Adults With Metastatic, Recurrent, or Progressive Cancer or HIV Infection

National Cancer Institute (NCI)

NCT01445145

COMPLETED Phase 4 66 participants

Improving Complete Endoscopic Mucosal Resection (EMR) of Colorectal Neoplasia

Mayo Clinic

NCT01471756

COMPLETED Phase 1 64 participants

Study of MK-4464 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced/Metastatic Solid Tumors (MK-4464-001)

Merck Sharp & Dohme

NCT05514444

COMPLETED Phase 1 64 participants

Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced Cancer

Bayer

NCT01392521

COMPLETED Phase 1 63 participants

Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors

Puma Biotechnology

NCT00838539

COMPLETED NA 60 participants

Expressive Helping for Chinese-Speaking Cancer Patients and Survivors

New York University

NCT03945734

COMPLETED NA 58 participants

Comparing Aerobic to Resistance Training in Recovery From Cancer

TriService Nursing Research Program

NCT00237926

COMPLETED Phase 1 58 participants

5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer

City of Hope Medical Center

NCT00359606

COMPLETED Phase 1 56 participants

A Study of ADH-1 in Combination With Normothermic Isolated Limb Infusion of Melphalan

Adherex Technologies

NCT00421811

COMPLETED NA 55 participants

Light Therapy to Increase Energy in Adolescents and Young Adults Newly Diagnosed With Solid Tumors: A Pilot Study

St. Jude Children's Research Hospital

NCT02429063

COMPLETED Phase 1 54 participants

Study Evaluating CMD-193 in Advanced Malignant Solid Tumors

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00161642

COMPLETED Phase 1 53 participants

Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors

National Cancer Institute (NCI)

NCT02723864

COMPLETED Phase 1 53 participants

Study Of Sunitinib Plus FOLFOX In Patients With Solid Tumors

Pfizer

NCT00599924

COMPLETED Phase 1 48 participants

Indocyanine Green for Solid Tumors

University of Pennsylvania

NCT02280954

COMPLETED Phase 1 47 participants

Study of Safety and Efficacy of Glufosfamide in Combination With Gemcitabine in Cancer

Threshold Pharmaceuticals

NCT00102752

COMPLETED NA 47 participants

The Families Addressing Cancer Together Intervention for Parents With Cancer

UNC Lineberger Comprehensive Cancer Center

NCT05377749

COMPLETED 47 participants

Genotoxicity Assessment for Patients Undergoing Radiation Treatment

Yuhchyau Chen

NCT00167427

COMPLETED 45 participants

Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic Osteomalacia

National Institute of Dental and Craniofacial Research (NIDCR)

NCT00099762

COMPLETED Phase 1 44 participants

A Study of Anti-VEGFR-3 Monoclonal Antibody IMC-3C5 in Subjects With Advanced Solid Tumors

Eli Lilly and Company

NCT01288989

COMPLETED Phase 1 43 participants

Study Of SU011248 In Combination With Paclitaxel/Carboplatin In Patients With Advanced Solid Tumors

Pfizer

NCT00511849

COMPLETED Phase 1 43 participants

A Study Of PF-03732010 In Patients With Advanced Solid Tumors

Pfizer

NCT00557505

COMPLETED 40 participants

Perceptions of Cell and Gene Therapies (CGT) for the Treatment of Cancer

GlaxoSmithKline

NCT03336567

COMPLETED Phase 1 40 participants

A Study of JNJ-63898081 in Participants With Advanced Stage Solid Tumors

Janssen Research & Development

NCT03926013

COMPLETED Phase 1 40 participants

Liposome Encapsulated SN38 (LE-SN38) in Patients With Advanced Cancer

INSYS Therapeutics

NCT00046540

COMPLETED Phase 2 38 participants

Detecting the Impact of Statin Therapy On Lowering Risk of Venous Thrombo-Embolic Events (DISOLVE)

University of Vermont

NCT01524653

COMPLETED Phase 1 35 participants

[177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-neoB Lesion Uptake

Advanced Accelerator Applications

NCT03872778

COMPLETED Phase 1 34 participants

Cancer Vaccine Targeting Brachyury Protein in Tumors

National Cancer Institute (NCI)

NCT01519817

COMPLETED Phase 1 34 participants

A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4

Astellas Pharma

NCT01409135

COMPLETED Phase 2 33 participants

NP2 Enkephalin For Treatment of Intractable Cancer Pain

Diamyd

NCT01291901

COMPLETED Phase 1 33 participants

Study of Cetuximab in Combination With Tarceva in Patients With Solid Tumors

Eli Lilly and Company

NCT00207077

COMPLETED Phase 1 33 participants

Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma

david andrews

NCT02507583

COMPLETED Phase 1 30 participants

Study to Determine the Maximum Tolerated Dose of LErafAON in Patients With Advanced Solid Tumors

INSYS Therapeutics

NCT00024661

COMPLETED Phase 1 30 participants

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02897778

COMPLETED Phase 1 30 participants

Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants

Corcept Therapeutics

NCT05347979

COMPLETED Phase 1 30 participants

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02909452

COMPLETED Phase 2 30 participants

A Pharmacokinetic Study of Valacyclovir in Pediatric Oncology Patients

Baylor College of Medicine

NCT00042328

COMPLETED Phase 1 29 participants

Dose Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2849330 in Subjects With Advanced Her3-Positive Solid Tumors

GlaxoSmithKline

NCT01966445

COMPLETED Phase 1 28 participants

Phase I of BIBW 2992/BIBF 1120 Combination Therapy in Solid Tumors

Boehringer Ingelheim

NCT00730821

COMPLETED Phase 2 23 participants

An Open Label Study of Oral Enzastaurin in Participants With Cancer

Eli Lilly and Company

NCT00309140

COMPLETED Phase 1 23 participants

A Study of MEHD7945A and Cobimetinib in Patients With Locally Advanced or Metastatic Cancers With Mutant KRAS

Genentech

NCT01986166

COMPLETED NA 23 participants

Yoga Intervention to Improve Pediatric Cancer Patients' Sleep & Life Quality and Parents' Well-Being

Connecticut Children's Medical Center

NCT02899117

COMPLETED Phase 1 19 participants

Effect of Rifampin on the Pharmacokinetics of Ixabepilone in Patients With Advanced Cancer

R-Pharm

NCT00207090

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Phase Distribution

PhaseTrial count
Phase 1 81
Phase 2 18
Phase 3 7
Phase 4 2

Named interventions

Most-linked intervention names on Neoplasms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
5 trials
Placebo Drug
5 trials
Fludarabine Drug
4 trials
Cyclophosphamide Drug
4 trials
Dostarlimab Drug
3 trials
Belrestotug Drug
2 trials
GSK5764227 Drug
2 trials
Dostarlimab Biological
2 trials

US sites by state

Facility locations filed on Neoplasms trials. A trial with sites in several states counts in each.

California 53 trials
Texas 46 trials
Florida 36 trials
New York 31 trials
Maryland 31 trials
Colorado 31 trials
Michigan 28 trials
Illinois 26 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Neoplasms page

160 registered trials, 50 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Neoplasms condition card totals 160 registered trials; most-linked intervention Gemcitabine; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.