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Neoplasms clinical trials
50 of 160 indexed Neoplasms trials are currently recruiting.
160 US clinical trials · 50 currently recruiting
Neoplasms is the subject of 160 registered US clinical trials on ClinicalTrials.gov, 50 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 99 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 15 of these trials.
The research picture
Neoplasms has 160 registered US clinical trials, 50 of them open to new participants right now, about 31% of the total.
- 50
- recruiting participants now
- 31%
- of trials open to enrollment
- 9
- in Phase 3–4 (later-stage)
- 15
- top sponsor: National Cancer Institute (NCI)
Active & Recent Trials
160 total, page 3 of 4
Genetic Exploration of the Molecular Basis of Malignancy in Adults
Sanford Health
NCT02416518
Biomarkers For Immune Checkpoint Inhibitors
Rhode Island Hospital
NCT04204434
Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor
Pfizer
NCT00454649
Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors
Novartis Pharmaceuticals
NCT02077933
Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in Patients
Bayer
NCT01915576
Collection of Blood, Bone Marrow, Tumor or Tissue Samples
National Cancer Institute (NCI)
NCT00043615
A Study Of Oral Palbociclib (PD-0332991), A Cyclin-Dependent Kinase Inhibitor, In Patients With Advanced Cancer
Pfizer
NCT00141297
Physical Activity and Healthy Eating Among Young Adult Cancer Survivors
UNC Lineberger Comprehensive Cancer Center
NCT05887401
An Exploratory Study of the Use of Five Wishes as a Tool for Advanced Care Planning in Young Adults With Metastatic, Recurrent, or Progressive Cancer or HIV Infection
National Cancer Institute (NCI)
NCT01445145
Improving Complete Endoscopic Mucosal Resection (EMR) of Colorectal Neoplasia
Mayo Clinic
NCT01471756
Study of MK-4464 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced/Metastatic Solid Tumors (MK-4464-001)
Merck Sharp & Dohme
NCT05514444
Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced Cancer
Bayer
NCT01392521
Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors
Puma Biotechnology
NCT00838539
Expressive Helping for Chinese-Speaking Cancer Patients and Survivors
New York University
NCT03945734
Comparing Aerobic to Resistance Training in Recovery From Cancer
TriService Nursing Research Program
NCT00237926
5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer
City of Hope Medical Center
NCT00359606
A Study of ADH-1 in Combination With Normothermic Isolated Limb Infusion of Melphalan
Adherex Technologies
NCT00421811
Light Therapy to Increase Energy in Adolescents and Young Adults Newly Diagnosed With Solid Tumors: A Pilot Study
St. Jude Children's Research Hospital
NCT02429063
Study Evaluating CMD-193 in Advanced Malignant Solid Tumors
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00161642
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors
National Cancer Institute (NCI)
NCT02723864
Study Of Sunitinib Plus FOLFOX In Patients With Solid Tumors
Pfizer
NCT00599924
Indocyanine Green for Solid Tumors
University of Pennsylvania
NCT02280954
Study of Safety and Efficacy of Glufosfamide in Combination With Gemcitabine in Cancer
Threshold Pharmaceuticals
NCT00102752
The Families Addressing Cancer Together Intervention for Parents With Cancer
UNC Lineberger Comprehensive Cancer Center
NCT05377749
Genotoxicity Assessment for Patients Undergoing Radiation Treatment
Yuhchyau Chen
NCT00167427
Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic Osteomalacia
National Institute of Dental and Craniofacial Research (NIDCR)
NCT00099762
A Study of Anti-VEGFR-3 Monoclonal Antibody IMC-3C5 in Subjects With Advanced Solid Tumors
Eli Lilly and Company
NCT01288989
Study Of SU011248 In Combination With Paclitaxel/Carboplatin In Patients With Advanced Solid Tumors
Pfizer
NCT00511849
A Study Of PF-03732010 In Patients With Advanced Solid Tumors
Pfizer
NCT00557505
Perceptions of Cell and Gene Therapies (CGT) for the Treatment of Cancer
GlaxoSmithKline
NCT03336567
A Study of JNJ-63898081 in Participants With Advanced Stage Solid Tumors
Janssen Research & Development
NCT03926013
Liposome Encapsulated SN38 (LE-SN38) in Patients With Advanced Cancer
INSYS Therapeutics
NCT00046540
Detecting the Impact of Statin Therapy On Lowering Risk of Venous Thrombo-Embolic Events (DISOLVE)
University of Vermont
NCT01524653
[177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-neoB Lesion Uptake
Advanced Accelerator Applications
NCT03872778
Cancer Vaccine Targeting Brachyury Protein in Tumors
National Cancer Institute (NCI)
NCT01519817
A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4
Astellas Pharma
NCT01409135
NP2 Enkephalin For Treatment of Intractable Cancer Pain
Diamyd
NCT01291901
Study of Cetuximab in Combination With Tarceva in Patients With Solid Tumors
Eli Lilly and Company
NCT00207077
Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma
david andrews
NCT02507583
Study to Determine the Maximum Tolerated Dose of LErafAON in Patients With Advanced Solid Tumors
INSYS Therapeutics
NCT00024661
Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors
Syndax Pharmaceuticals
NCT02897778
Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants
Corcept Therapeutics
NCT05347979
Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors
Syndax Pharmaceuticals
NCT02909452
A Pharmacokinetic Study of Valacyclovir in Pediatric Oncology Patients
Baylor College of Medicine
NCT00042328
Dose Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2849330 in Subjects With Advanced Her3-Positive Solid Tumors
GlaxoSmithKline
NCT01966445
Phase I of BIBW 2992/BIBF 1120 Combination Therapy in Solid Tumors
Boehringer Ingelheim
NCT00730821
An Open Label Study of Oral Enzastaurin in Participants With Cancer
Eli Lilly and Company
NCT00309140
A Study of MEHD7945A and Cobimetinib in Patients With Locally Advanced or Metastatic Cancers With Mutant KRAS
Genentech
NCT01986166
Yoga Intervention to Improve Pediatric Cancer Patients' Sleep & Life Quality and Parents' Well-Being
Connecticut Children's Medical Center
NCT02899117
Effect of Rifampin on the Pharmacokinetics of Ixabepilone in Patients With Advanced Cancer
R-Pharm
NCT00207090
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 81 |
| Phase 2 | 18 |
| Phase 3 | 7 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Neoplasms Trial Landscape
160 indexed Neoplasms studies · 50 recruiting (31%).
Phase mix: 9 late (III/IV) vs 99 early (I/II).
Top sponsor: National Cancer Institute (NCI) (15 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Neoplasms?
PlainTrial tracks 160 US clinical trials for Neoplasms, of which 50 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Neoplasms?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.