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ClinicalTrials.gov 50 recruiting now official registry

Neoplasms clinical trials

50 of 160 indexed Neoplasms trials are currently recruiting.

160 US clinical trials · 50 currently recruiting

Neoplasms is the subject of 160 registered US clinical trials on ClinicalTrials.gov, 50 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 99 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 15 of these trials.

The research picture

Neoplasms has 160 registered US clinical trials, 50 of them open to new participants right now, about 31% of the total.

50
recruiting participants now
31%
of trials open to enrollment
9
in Phase 3–4 (later-stage)
15
top sponsor: National Cancer Institute (NCI)
Phase 181Phase 218Phase 37Phase 42

Active & Recent Trials

160 total, page 3 of 4

COMPLETED 120 participants

Genetic Exploration of the Molecular Basis of Malignancy in Adults

Sanford Health

NCT02416518

COMPLETED 119 participants

Biomarkers For Immune Checkpoint Inhibitors

Rhode Island Hospital

NCT04204434

COMPLETED Phase 1 102 participants

Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor

Pfizer

NCT00454649

COMPLETED Phase 1 79 participants

Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors

Novartis Pharmaceuticals

NCT02077933

COMPLETED Phase 1 79 participants

Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in Patients

Bayer

NCT01915576

COMPLETED 74 participants

Collection of Blood, Bone Marrow, Tumor or Tissue Samples

National Cancer Institute (NCI)

NCT00043615

COMPLETED Phase 1 74 participants

A Study Of Oral Palbociclib (PD-0332991), A Cyclin-Dependent Kinase Inhibitor, In Patients With Advanced Cancer

Pfizer

NCT00141297

COMPLETED NA 72 participants

Physical Activity and Healthy Eating Among Young Adult Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT05887401

COMPLETED 70 participants

An Exploratory Study of the Use of Five Wishes as a Tool for Advanced Care Planning in Young Adults With Metastatic, Recurrent, or Progressive Cancer or HIV Infection

National Cancer Institute (NCI)

NCT01445145

COMPLETED Phase 4 66 participants

Improving Complete Endoscopic Mucosal Resection (EMR) of Colorectal Neoplasia

Mayo Clinic

NCT01471756

COMPLETED Phase 1 64 participants

Study of MK-4464 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced/Metastatic Solid Tumors (MK-4464-001)

Merck Sharp & Dohme

NCT05514444

COMPLETED Phase 1 64 participants

Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced Cancer

Bayer

NCT01392521

COMPLETED Phase 1 63 participants

Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors

Puma Biotechnology

NCT00838539

COMPLETED NA 60 participants

Expressive Helping for Chinese-Speaking Cancer Patients and Survivors

New York University

NCT03945734

COMPLETED NA 58 participants

Comparing Aerobic to Resistance Training in Recovery From Cancer

TriService Nursing Research Program

NCT00237926

COMPLETED Phase 1 58 participants

5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer

City of Hope Medical Center

NCT00359606

COMPLETED Phase 1 56 participants

A Study of ADH-1 in Combination With Normothermic Isolated Limb Infusion of Melphalan

Adherex Technologies

NCT00421811

COMPLETED NA 55 participants

Light Therapy to Increase Energy in Adolescents and Young Adults Newly Diagnosed With Solid Tumors: A Pilot Study

St. Jude Children's Research Hospital

NCT02429063

COMPLETED Phase 1 54 participants

Study Evaluating CMD-193 in Advanced Malignant Solid Tumors

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00161642

COMPLETED Phase 1 53 participants

Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors

National Cancer Institute (NCI)

NCT02723864

COMPLETED Phase 1 53 participants

Study Of Sunitinib Plus FOLFOX In Patients With Solid Tumors

Pfizer

NCT00599924

COMPLETED Phase 1 48 participants

Indocyanine Green for Solid Tumors

University of Pennsylvania

NCT02280954

COMPLETED Phase 1 47 participants

Study of Safety and Efficacy of Glufosfamide in Combination With Gemcitabine in Cancer

Threshold Pharmaceuticals

NCT00102752

COMPLETED NA 47 participants

The Families Addressing Cancer Together Intervention for Parents With Cancer

UNC Lineberger Comprehensive Cancer Center

NCT05377749

COMPLETED 47 participants

Genotoxicity Assessment for Patients Undergoing Radiation Treatment

Yuhchyau Chen

NCT00167427

COMPLETED 45 participants

Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic Osteomalacia

National Institute of Dental and Craniofacial Research (NIDCR)

NCT00099762

COMPLETED Phase 1 44 participants

A Study of Anti-VEGFR-3 Monoclonal Antibody IMC-3C5 in Subjects With Advanced Solid Tumors

Eli Lilly and Company

NCT01288989

COMPLETED Phase 1 43 participants

Study Of SU011248 In Combination With Paclitaxel/Carboplatin In Patients With Advanced Solid Tumors

Pfizer

NCT00511849

COMPLETED Phase 1 43 participants

A Study Of PF-03732010 In Patients With Advanced Solid Tumors

Pfizer

NCT00557505

COMPLETED 40 participants

Perceptions of Cell and Gene Therapies (CGT) for the Treatment of Cancer

GlaxoSmithKline

NCT03336567

COMPLETED Phase 1 40 participants

A Study of JNJ-63898081 in Participants With Advanced Stage Solid Tumors

Janssen Research & Development

NCT03926013

COMPLETED Phase 1 40 participants

Liposome Encapsulated SN38 (LE-SN38) in Patients With Advanced Cancer

INSYS Therapeutics

NCT00046540

COMPLETED Phase 2 38 participants

Detecting the Impact of Statin Therapy On Lowering Risk of Venous Thrombo-Embolic Events (DISOLVE)

University of Vermont

NCT01524653

COMPLETED Phase 1 35 participants

[177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-neoB Lesion Uptake

Advanced Accelerator Applications

NCT03872778

COMPLETED Phase 1 34 participants

Cancer Vaccine Targeting Brachyury Protein in Tumors

National Cancer Institute (NCI)

NCT01519817

COMPLETED Phase 1 34 participants

A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4

Astellas Pharma

NCT01409135

COMPLETED Phase 2 33 participants

NP2 Enkephalin For Treatment of Intractable Cancer Pain

Diamyd

NCT01291901

COMPLETED Phase 1 33 participants

Study of Cetuximab in Combination With Tarceva in Patients With Solid Tumors

Eli Lilly and Company

NCT00207077

COMPLETED Phase 1 33 participants

Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma

david andrews

NCT02507583

COMPLETED Phase 1 30 participants

Study to Determine the Maximum Tolerated Dose of LErafAON in Patients With Advanced Solid Tumors

INSYS Therapeutics

NCT00024661

COMPLETED Phase 1 30 participants

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02897778

COMPLETED Phase 1 30 participants

Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants

Corcept Therapeutics

NCT05347979

COMPLETED Phase 1 30 participants

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02909452

COMPLETED Phase 2 30 participants

A Pharmacokinetic Study of Valacyclovir in Pediatric Oncology Patients

Baylor College of Medicine

NCT00042328

COMPLETED Phase 1 29 participants

Dose Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2849330 in Subjects With Advanced Her3-Positive Solid Tumors

GlaxoSmithKline

NCT01966445

COMPLETED Phase 1 28 participants

Phase I of BIBW 2992/BIBF 1120 Combination Therapy in Solid Tumors

Boehringer Ingelheim

NCT00730821

COMPLETED Phase 2 23 participants

An Open Label Study of Oral Enzastaurin in Participants With Cancer

Eli Lilly and Company

NCT00309140

COMPLETED Phase 1 23 participants

A Study of MEHD7945A and Cobimetinib in Patients With Locally Advanced or Metastatic Cancers With Mutant KRAS

Genentech

NCT01986166

COMPLETED NA 23 participants

Yoga Intervention to Improve Pediatric Cancer Patients' Sleep & Life Quality and Parents' Well-Being

Connecticut Children's Medical Center

NCT02899117

COMPLETED Phase 1 19 participants

Effect of Rifampin on the Pharmacokinetics of Ixabepilone in Patients With Advanced Cancer

R-Pharm

NCT00207090

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Phase Distribution

PhaseTrial count
Phase 1 81
Phase 2 18
Phase 3 7
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Neoplasms Trial Landscape

160 indexed Neoplasms studies · 50 recruiting (31%).

Phase mix: 9 late (III/IV) vs 99 early (I/II).

Top sponsor: National Cancer Institute (NCI) (15 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Neoplasms?

PlainTrial tracks 160 US clinical trials for Neoplasms, of which 50 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.