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Mild Traumatic Brain Injury: early-phase trial registry
28 of 44 indexed Mild Traumatic Brain Injury trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #330 of 28,707 conditions by registered trial count.
44 US clinical trials · 28 currently recruiting · #330 of 28,707 conditions by registered trial count
Mild Traumatic Brain Injury: 44 US clinical trials tracked, 28 recruiting.
Mild Traumatic Brain Injury is the subject of 44 registered US clinical trials on ClinicalTrials.gov, 28 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 7 of these trials.
Enrollment posture brief
Registry condition mild-traumatic-brain-injury
OPEN 28 | RECR 64% | LATE 2 | EARLY 10 | RANK #330 | SPON 7
Volume-matched condition peers
Nearest open-share peer: Advanced Melanoma (64% recruiting · 22 trials)
Mild Traumatic Brain Injury lists 28 open slots (64% of 44 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Mild Traumatic Brain Injury on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Mild Traumatic Brain Injury is recruiting above its size-band peers.
28 of 44 indexed trials (63.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Mild Traumatic Brain Injury research.
VA Office of Research and Development accounts for 7 of 44 trials (15.9%). 30 distinct sponsors appear on at least one study for this condition label.
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Typical Mild Traumatic Brain Injury enrolment sits around 80 participants.
Median target enrolment is 80 among the 44 trials that report a genuine target (sentinel values excluded). 26 of those (59.1%) plan for fewer than 100 participants.
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Mild Traumatic Brain Injury research is mostly interventional.
36 interventional and 8 observational studies make up this index (81.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
44 total, page 1 of 1
Utilizing Electronic Clinical Decision Support to Enhance mTBI Care at the Primary Care Point of Entry
Children's Hospital of Philadelphia
NCT06693778
Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)
VA Office of Research and Development
NCT04124029
Risk Stratification in Children With Concussion
Duke University
NCT05825027
Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI
Henry M. Jackson Foundation for the Advancement of Military Medicine
NCT05049057
Facilitating Access to Specialty Treatment
Children's Hospital of Philadelphia
NCT05741411
Neuromodulation and Neurorehabilitation for mTBI
Northwestern University
NCT03819608
rTMS for Military TBI-related Depression
Henry M. Jackson Foundation for the Advancement of Military Medicine
NCT05426967
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)
VA Office of Research and Development
NCT04867317
Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)
United States Naval Medical Center, San Diego
NCT06413173
Behavioral Insomnia Treatment in Mild Traumatic Brain Injury
The University of Texas Health Science Center at San Antonio
NCT06551987
Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms
Virginia Commonwealth University
NCT07071350
Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)
Foundation for Advancing Veterans' Health Research
NCT06333990
Treatment Optimization of Brain-injured Warfighters
United States Naval Medical Center, San Diego
NCT06561100
Passive Neurosensory Reintegration Training as a Tool to Augment Mild Traumatic Brain Injury
University of Miami
NCT07356167
Auditory Plasticity Training
The University of Texas Health Science Center at San Antonio
NCT06628505
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
University of California, Los Angeles
NCT06073886
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
University of Texas Southwestern Medical Center
NCT05446584
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
University of California, San Diego
NCT05682677
Vestibular Rehabilitation App for Adults With Dizziness Related to mTBI
Mountain Home Research & Education Corporation
NCT06222450
Regulation of Emotion, Sleep Extension, and mTBI
Merrimack College
NCT06883006
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
State University of New York - Upstate Medical University
NCT06112093
Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline
University of Wisconsin, Madison
NCT07044596
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
VA Office of Research and Development
NCT05647044
Concussion Recovery and Support Program
Seattle Children's Hospital
NCT07097792
Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans
University of Alabama at Birmingham
NCT06217575
Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury
VA Office of Research and Development
NCT06109909
Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms
University of Minnesota
NCT07246993
Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury
State University of New York at Buffalo
NCT05762796
Acute and Mild TBI Injury in Military and Civilian Population Using Advanced MR Imaging
The Geneva Foundation
NCT05101239
Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel
Henry M. Jackson Foundation for the Advancement of Military Medicine
NCT05147506
Enhancing Brain Training With Virtual Reality
University of Rochester
NCT03582579
Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test
University of Pittsburgh
NCT06276660
Pilot rTMS for AUD+mTBI
VA Office of Research and Development
NCT03995173
Deployment Related Mild Traumatic Brain Injury (mTBI)
The Defense and Veterans Brain Injury Center
NCT01847040
The Use of the VOMS Tool With Military Personnel to Track mTBI Recovery and RTD Status
University of Pittsburgh
NCT02634944
Non-blinded Data Collection Study of Concussion Using the BrainPulse(TM)
Jan Medical
NCT02812225
Cognitive-Communication Screening and Early Therapy for Adults With Mild TBI
Northern Arizona University
NCT03230656
Eyetracking and Neurovision Rehabilitation of Oculomotor Dysfunction in Mild Traumatic Brain Injury
Hennepin Healthcare Research Institute
NCT03319966
Biological Signatures, Probiotic Among Those With mTBI and PTSD
VA Office of Research and Development
NCT02723344
Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI)
Virginia Commonwealth University
NCT01220713
Incremental Velocity Error as a New Treatment in Vestibular Rehabilitation
Johns Hopkins University
NCT03846830
Clinical Trial of a Rehabilitation Game - SuperBetter
Ohio State University
NCT01398566
Neuromodulation and Yoga for Mild Traumatic Brain Injury and Chronic Pain
VA Office of Research and Development
NCT04517604
Neural Injury in Adolescents With Concussion
Children's Hospital of Philadelphia
NCT03011983
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 6 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Mild Traumatic Brain Injury records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Mild Traumatic Brain Injury trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Mild Traumatic Brain Injury page
44 registered trials, 28 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 28 Mild Traumatic Brain Injury trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Mild Traumatic Brain Injury trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Mild Traumatic Brain Injury condition card totals 44 registered trials; most-linked intervention Early cognitive-communication therapy; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.