Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05147506 · ClinicalTrials.gov registry record · NA
Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel
A NA study of Depressive Symptoms and Mild Traumatic Brain Injury, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- Active
- Registry status
- NA
- Development phase
- 113
- Enrollment target
- 1
- Study location
NCT05147506: Active NA study of Depressive Symptoms and Mild Traumatic Brain Injury, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
NCT05147506 is a NA study of Depressive Symptoms and Mild Traumatic Brain Injury that is active but no longer recruiting, run by Henry M. Jackson Foundation for the Advancement of Military Medicine. The registered enrollment target is 113 participants, below the 260-participant average among 60 other Depressive Symptoms trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05147506, a NA study of Depressive Symptoms and Mild Traumatic Brain Injury, is active but no longer recruiting, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 113 participants
- Enrollment target
- 1
- Study location
Study Summary
The Center for Neuroscience and Regenerative Medicine (CNRM) Clinical Trials Unit has developed the first cognitive-behavioral therapy (CBT) digital therapeutic (DTx) mobile application to counteract depressive symptoms in military service members and veterans with a history of mild traumatic brain injury (mTBI). This trial will assess the efficacy of the novel CBT-DTx for depression following mTBI compared to an educational comparison DTx.
Conditions Studied
Interventions
- DEVICE CNRM DTx
- OTHER Psychoeducation Comparison
Study Locations (1)
Maryland
- Remote Recruitment: Center for Neuroscience and Regenerative Medicine - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 113 participants |
| Start Date | 2022-06-22 |
| Est. Completion | 2025-01-01 |
| Phase | NA |
What the registry record for NCT05147506 still lists
NCT05147506 is an interventional study that assigns participants to a tested intervention. The registered 113 participants enrollment target is mid-sized for trials with a published cap, below the 260-participant average among 60 other Depressive Symptoms trials with a reported enrollment target (57% lower).
The record links to 2 conditions, with Depressive Symptoms appearing as the primary indexed condition, and to 2 interventions - of which CNRM DTx is the first listed.
NCT05147506 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05147506 about?
NCT05147506 is a clinical study titled "Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel". The Center for Neuroscience and Regenerative Medicine (CNRM) Clinical Trials Unit has developed the first cognitive-behavioral therapy (CBT) digital therapeutic (DTx) mobile application to counteract depressive symptoms in military service members and veterans with a history of mild traumatic brain ...
What is the current status of trial NCT05147506?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 113 participants. The study started on 2022-06-22. Estimated completion is 2025-01-01.
What conditions does trial NCT05147506 study?
This clinical trial studies the following conditions: Depressive Symptoms, Mild Traumatic Brain Injury.
What interventions are being tested in trial NCT05147506?
The interventions under investigation include: CNRM DTx (DEVICE), Psychoeducation Comparison (OTHER).
Who is sponsoring clinical trial NCT05147506?
This trial is sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine, which has 60 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05147506 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depressive Symptoms
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05147506's enrollment target sits among peer trials
113 28th of 60 higher than 33 of 60 other Depressive Symptoms trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depressive Symptoms trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Caregiver Stress and Sleep Study
RECRUITING · NA
-
IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)
RECRUITING · NA
-
Mood and Thought Process Study
RECRUITING · NA
-
Michigan Men's Diabetes Project III(MenDIII): Mind and Motion
RECRUITING · NA
-
A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior
RECRUITING · NA
-
Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00748254 · 113 participants
Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis
- NCT04753190 · 113 participants · NA
Light Timing Study
- NCT05799248 · 113 participants · Phase 3
Role of rhPSMA-7.3 PET/CT Imaging in Men With High-Risk Prostate Cancer Following Conventional Imaging and Associated Changes in Medical Management
- NCT07216105 · 113 participants · Phase 1
FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI