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NCT05049057 · ClinicalTrials.gov registry record · Phase 2
Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI
A Phase 2 study of Mild Traumatic Brain Injury and Posttraumatic Headache, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 404
- Enrollment target
- 4
- Study locations
NCT05049057 is a Phase 2 study of Mild Traumatic Brain Injury and Posttraumatic Headache that is actively recruiting participants, run by Henry M. Jackson Foundation for the Advancement of Military Medicine. The registered enrollment target is 404 participants, above the 211-participant average among 43 other Mild Traumatic Brain Injury trials with a reported enrollment target (91% higher). The trial reports 4 study locations across 4 states.
The verdict
NCT05049057, a Phase 2 study of Mild Traumatic Brain Injury and Posttraumatic Headache, is actively recruiting participants, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 404 participants
- Enrollment target
- 4
- Study locations
Study Summary
This study aims to assess the effect and safety of erenumab compared to placebo for the treatment of acute posttraumatic headache (PTH) in military service members and civilians with mild traumatic brain injury (mTBI).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Erenumab 140 Mg/mL Subcutaneous Solution
Study Locations (4)
North Carolina
- Womack Army Medical Center - Fort Liberty - Fort Bragg
Pennsylvania
- University of Pittsburgh Concussion Research Laboratory - Pittsburgh
Texas
- William Beaumont Army Medical Center - El Paso
Washington
- Madigan Army Medical Center - Tacoma
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 404 participants |
| Start Date | 2022-07-19 |
| Est. Completion | 2027-05-19 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05049057
The ClinicalTrials.gov registry entry for NCT05049057 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 404 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 211-participant average among 43 other Mild Traumatic Brain Injury trials with a reported enrollment target (91% higher). The listed sponsor is Henry M. Jackson Foundation for the Advancement of Military Medicine, which has 60 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Mild Traumatic Brain Injury appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05049057 reports 4 study locations spanning 4 distinct geographic areas - top geographies include North Carolina, Pennsylvania, Texas.
Frequently Asked Questions
What is clinical trial NCT05049057 about?
NCT05049057 is a clinical study titled "Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI". This study aims to assess the effect and safety of erenumab compared to placebo for the treatment of acute posttraumatic headache (PTH) in military service members and civilians with mild traumatic brain injury (mTBI).
What is the current status of trial NCT05049057?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 404 participants. The study started on 2022-07-19. Estimated completion is 2027-05-19.
What conditions does trial NCT05049057 study?
This clinical trial studies the following conditions: Mild Traumatic Brain Injury, Posttraumatic Headache.
What interventions are being tested in trial NCT05049057?
The interventions under investigation include: Placebo (DRUG), Erenumab 140 Mg/mL Subcutaneous Solution (DRUG).
Who is sponsoring clinical trial NCT05049057?
This trial is sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine, which has 60 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05049057 being conducted?
This trial has 4 study locations across North Carolina, Pennsylvania, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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