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NCT05682677 · ClinicalTrials.gov registry record · NA
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
A NA study of Depression and Mild Traumatic Brain Injury, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- NA
- Development phase
- 72
- Enrollment target
- 1
- Study location
NCT05682677 is a NA study of Depression and Mild Traumatic Brain Injury that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 72 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05682677, a NA study of Depression and Mild Traumatic Brain Injury, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- NA
- Development phase
- 72 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans, and civilians who have sustained a mild TBI. Participants will receive PACT plus 20 sessions of iTBS or sham iTBS over 4 weeks. Assessments will occur at baseline, 2 weeks, 4 weeks, and 8 weeks. Researchers will compare the PACT+iTBS group to the PACT+sham iTBS group to see if PACT+iTBS is associated with more depression improvement.
Conditions Studied
Interventions
- DEVICE iTBS
- DEVICE sham iTBS
- BEHAVIORAL Personalized, Augmented Cognitive Training (PACT)
Study Locations (1)
California
- UCSD - La Jolla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2023-09-19 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05682677
The ClinicalTrials.gov registry entry for NCT05682677 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (91% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 3 interventions - of which iTBS is the first listed.
NCT05682677 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05682677 about?
NCT05682677 is a clinical study titled "Combined Neuromodulation and Cognitive Training for Post-mTBI Depression". The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans, and civilians who have sustained a mild TBI. Participants will receive P...
What is the current status of trial NCT05682677?
This trial is currently recruiting. It is a NA study. The enrollment target is 72 participants. The study started on 2023-09-19. Estimated completion is 2026-06-30.
What conditions does trial NCT05682677 study?
This clinical trial studies the following conditions: Depression, Mild Traumatic Brain Injury, Concussion, Brain.
What interventions are being tested in trial NCT05682677?
The interventions under investigation include: iTBS (DEVICE), sham iTBS (DEVICE), Personalized, Augmented Cognitive Training (PACT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05682677?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05682677 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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