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Alcohol Dependence: early-phase trial registry
8 of 44 indexed Alcohol Dependence trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #330 of 28,707 conditions by registered trial count.
44 US clinical trials · 8 currently recruiting · #330 of 28,707 conditions by registered trial count
Alcohol Dependence: 44 US clinical trials tracked, 8 recruiting.
Alcohol Dependence is the subject of 44 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute on Alcohol Abuse and Alcoholism (NIAAA), running 8 of these trials.
Enrollment posture brief
Registry condition alcohol-dependence
OPEN 8 | RECR 18% | LATE 6 | EARLY 22 | RANK #330 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome (18% recruiting · 22 trials)
Alcohol Dependence lists 8 open slots (18% of 44 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Alcohol Dependence on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Alcohol Dependence is recruiting below its size-band peers.
8 of 44 indexed trials (18.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Alcohol Dependence research.
National Institute on Alcohol Abuse and Alcoholism (NIAAA) accounts for 8 of 44 trials (18.2%). 27 distinct sponsors appear on at least one study for this condition label.
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Typical Alcohol Dependence enrolment sits around 90 participants.
Median target enrolment is 90 among the 44 trials that report a genuine target (sentinel values excluded). 25 of those (56.8%) plan for fewer than 100 participants.
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Alcohol Dependence research is mostly interventional.
41 interventional and 3 observational studies make up this index (93.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
44 total, page 1 of 1
Substance Abuse Pre-Treatment Screening Study
The University of Texas Health Science Center, Houston
NCT00439049
Characterization Imaging Instruments in Alcoholics and Non-Alcoholics
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02108080
Behavioral and Functional Task Development, Implementation, and Testing
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02108054
Virtual Incentive Treatment for Alcohol
Washington State University
NCT06265506
Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)
Brainsway
NCT07216872
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
University of Iowa
NCT06405607
The Impact of Heavy Alcohol Use on Saliva and Oral Health
National Institutes of Health Clinical Center (CC)
NCT06684483
Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study
Wake Forest University Health Sciences
NCT06770556
Telehealth Treatment for Alcohol Use Disorder
Ria Health
NCT05747703
Making Alcoholics Anonymous Easier
Alcohol Research Group
NCT01382316
ALK33-005: A Study of ALKS33 (RDC-0313) in Adults With Alcohol Dependence
Alkermes
NCT00981617
Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism
Medical University of South Carolina
NCT00920829
Drug Therapy for Alcohol Dependence in Alaska Natives (Naltrexone/Sertraline)
Yale University
NCT00000451
A Study in the Treatment of Alcohol Dependence.
Eli Lilly and Company
NCT00805441
Intensive Intervention for Smokers - 6
University of California, San Francisco
NCT00217984
A Therapeutic Workplace for Alcohol Dependence
Johns Hopkins University
NCT00183144
Gabapentin Treatment of Alcohol Dependence
The Scripps Research Institute
NCT00391716
Facilitating Aftercare for Alcohol Detox Patients
State University of New York at Buffalo
NCT00513708
Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
University of Washington
NCT00619255
Chronic Alcohol, Stress Inflammatory Response and Relapse Risk
Yale University
NCT02193204
Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00006204
Mifepristone Treatment of Alcohol Use Disorder
The Scripps Research Institute
NCT02179749
Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
Yale University
NCT00744055
The MEADOW PROJECT (Mending the Effects of Alcohol and Depression on Women) and The Bridge Program (Connecting Recovery Treatment and Behavioral Health)
University of Rochester
NCT00851669
Aripiprazole and Topiramate on Free-Choice Alcohol Use
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00884884
Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking
Northwell Health
NCT00665249
Combined Treatment for Cocaine-Alcohol Dependence - 1
The University of Texas Health Science Center, Houston
NCT00218569
Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders
Medical University of South Carolina
NCT01338506
A Tailored Physical Activity Smartphone App for Patients With Alcohol Dependence
Butler Hospital
NCT02958280
The Effect of Naltrexone on Alcohol Craving and on Brain Activity During Alcohol Infusion
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00667771
Effect of LY686017 on Alcohol Craving
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT00310427
An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence
Medical University of South Carolina
NCT00667875
Oral vs. Injectable Naltrexone for Hospitalized Veterans With Alcohol Dependence
University of Wisconsin, Madison
NCT01856712
Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence
Medical University of South Carolina
NCT01055171
Zonisamide vs. Placebo in the Treatment of Alcohol Dependence
UConn Health
NCT00595556
Gabapentin for Abstinence Initiation in Alcohol Dependence
New York State Psychiatric Institute
NCT01141049
Baclofen for Treating Anxiety and Alcoholism
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT01751386
Cell Phone Technology Targeting ART and Naltrexone Adherence and Alcohol Use
University of California, Los Angeles
NCT02603471
Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics
VA Office of Research and Development
NCT01657760
Aripiprazole Effects on Alcohol Reactivity and Consumption
Medical University of South Carolina
NCT00183235
Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence
Yale University
NCT01847469
Oxytocin Treatment of Alcohol Dependence
University of North Carolina, Chapel Hill
NCT02251912
A Novel Compound for Alcoholism Treatment
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02039349
Modification of Cognitive Processing Therapy (CPT-C) for PTSD and Alcohol Dependence
Yale University
NCT00639288
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 19 |
| Phase 3 | 3 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Alcohol Dependence records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Alcohol Dependence trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Alcohol Dependence page
44 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Alcohol Dependence trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute on Alcohol Abuse and Alcoholism (NIAAA) sponsors the most Alcohol Dependence trials on record, review their full trial history before evaluating a specific study. See National Institute on Alcohol Abuse and Alcoholism (NIAAA)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcohol Dependence condition card totals 44 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.