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NCT07044596 · ClinicalTrials.gov registry record · NA

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

A NA study of Mild Traumatic Brain Injury and Post-Concussion Syndrome, sponsored by University of Wisconsin, Madison.

Recruiting
Registry status
NA
Development phase
55
Enrollment target
1
Study location

NCT07044596 is a NA study of Mild Traumatic Brain Injury and Post-Concussion Syndrome that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 55 participants, below the 219-participant average among 43 other Mild Traumatic Brain Injury trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07044596, a NA study of Mild Traumatic Brain Injury and Post-Concussion Syndrome, is actively recruiting participants, sponsored by University of Wisconsin, Madison.

RECRUITING
Registry status
NA
Development phase
55 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research is to demonstrate that mild stimulation of a nerve (trigeminal nerve) in the head can modulate blood flow in the brain. The modulated blood flow will restore the flow of cerebrospinal fluid (CSF) and this in turn can help improve waste clearance in the brain and prevent build up that may lead to disease.

Conditions Studied

Mild Traumatic Brain Injury Post-Concussion Syndrome

Interventions

  • DEVICE Magnetic Resonance Imaging (MRI)
  • DEVICE Functional near-infrared spectroscopy (fNIRS)
  • DEVICE V1 stimulation electrodes

Study Locations (1)

Wisconsin

  • University of Wisconsin - Madison - Madison

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2025-11-13
Est. Completion 2026-08
Phase NA

Sponsor

University of Wisconsin, Madison

1,039 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07044596

The ClinicalTrials.gov registry entry for NCT07044596 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 219-participant average among 43 other Mild Traumatic Brain Injury trials with a reported enrollment target (75% lower). The listed sponsor is University of Wisconsin, Madison, which has 1,039 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Mild Traumatic Brain Injury appearing as the primary indexed condition, and to 3 interventions - of which Magnetic Resonance Imaging (MRI) is the first listed.

NCT07044596 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT07044596 about?

NCT07044596 is a clinical study titled "Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline". The purpose of this research is to demonstrate that mild stimulation of a nerve (trigeminal nerve) in the head can modulate blood flow in the brain. The modulated blood flow will restore the flow of cerebrospinal fluid (CSF) and this in turn can help improve waste clearance in the brain and prevent ...

What is the current status of trial NCT07044596?

This trial is currently recruiting. It is a NA study. The enrollment target is 55 participants. The study started on 2025-11-13. Estimated completion is 2026-08.

What conditions does trial NCT07044596 study?

This clinical trial studies the following conditions: Mild Traumatic Brain Injury, Post-Concussion Syndrome.

What interventions are being tested in trial NCT07044596?

The interventions under investigation include: Magnetic Resonance Imaging (MRI) (DEVICE), Functional near-infrared spectroscopy (fNIRS) (DEVICE), V1 stimulation electrodes (DEVICE).

Who is sponsoring clinical trial NCT07044596?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07044596 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.