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Malignant Solid Neoplasm: early-phase trial registry
94 of 177 indexed Malignant Solid Neoplasm trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #62 of 28,707 conditions by registered trial count.
177 US clinical trials · 94 currently recruiting · #62 of 28,707 conditions by registered trial count
Malignant Solid Neoplasm: 177 US clinical trials tracked, 94 recruiting.
Malignant Solid Neoplasm is the subject of 177 registered US clinical trials on ClinicalTrials.gov, 94 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 42 of these trials.
Enrollment posture brief
Registry condition malignant-solid-neoplasm
OPEN 94 | RECR 53% | LATE 14 | EARLY 46 | RANK #62 | SPON 42
Volume-matched condition peers
Nearest open-share peer: Endometriosis (53% recruiting · 49 trials)
Malignant Solid Neoplasm lists 94 open slots (53% of 177 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Malignant Solid Neoplasm on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Malignant Solid Neoplasm is recruiting above its size-band peers.
94 of 177 indexed trials (53.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Malignant Solid Neoplasm research.
M.D. Anderson Cancer Center accounts for 42 of 177 trials (23.7%). 29 distinct sponsors appear on at least one study for this condition label.
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Typical Malignant Solid Neoplasm enrolment sits around 105 participants.
Median target enrolment is 105 among the 177 trials that report a genuine target (sentinel values excluded). 84 of those (47.5%) plan for fewer than 100 participants.
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Malignant Solid Neoplasm research is mostly interventional.
128 interventional and 49 observational studies make up this index (72.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
177 total, page 2 of 4
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
Mayo Clinic
NCT03750227
Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer
Mayo Clinic
NCT07477886
Communication Issues in Patient and Provider Discussions of Immunotherapy
Emory University
NCT05873608
Weighted Blanket Use to Reduce Anxiety in Oncology Patients
Ohio State University Comprehensive Cancer Center
NCT06089408
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
Children's Oncology Group
NCT05711667
Investigating Memory and Physical Activity After Cancer Treatment in Survivors of Adolescent and Young Adult Cancers
Mayo Clinic
NCT06880861
Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer
OHSU Knight Cancer Institute
NCT06562777
Intravital Microscopy in Human Solid Tumors
Mayo Clinic
NCT03823144
A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients
University of Michigan Rogel Cancer Center
NCT07291414
Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy
Mayo Clinic
NCT06723041
Transportation for Cancer Care Navigation Tool for Reducing Travel Barriers Among Patients With Solid Tumors Receiving Radiation Therapy
Emory University
NCT06541158
CREATE: Art for Children With Cancer
OHSU Knight Cancer Institute
NCT06342453
Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines
M.D. Anderson Cancer Center
NCT02962661
Cryocompression With or Without Cilostazol for the Prevention of Paclitaxel-induced Neuropathy in Patients With Gynecological Cancers
Emory University
NCT06492070
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
M.D. Anderson Cancer Center
NCT04565665
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
National Cancer Institute (NCI)
NCT06126276
Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell Transplant
M.D. Anderson Cancer Center
NCT04678427
Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting
City of Hope Medical Center
NCT07126301
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Children's Oncology Group
NCT06513962
Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers
City of Hope Medical Center
NCT05722288
Solution-Focused Brief Therapy for Support of Psychological Distress in Adolescent and Young Adult Cancer Survivors
University of Michigan Rogel Cancer Center
NCT06941324
Group Curriculum for Improving Survivorship Outcomes in Adolescent and Young Adult Cancer Survivors
Mayo Clinic
NCT05584449
Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas
Roswell Park Cancer Institute
NCT06202066
Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction
Roswell Park Cancer Institute
NCT06306638
Different Types of Massage Therapy to Reduce Anxiety During Chemotherapy Infusion in Patients With Cancer
City of Hope Medical Center
NCT07184294
A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment
University of Michigan Rogel Cancer Center
NCT07365007
L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance
City of Hope Medical Center
NCT07220447
Data-Driven Strategies for Patient Engagement About Cancer Clinical Trials
University of Southern California
NCT07456436
Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers
Wake Forest University Health Sciences
NCT06709404
Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors
City of Hope Medical Center
NCT06500377
Voices: Messages of Wisdom and Hope in the Face of Illness
Mayo Clinic
NCT07381179
Evaluation of Early Identification of Cognitive Side Effects of Immunotherapy
Masonic Cancer Center, University of Minnesota
NCT06414278
Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma
City of Hope Medical Center
NCT05830058
Mobile App to Help Survivors of Childhood Cancer Navigate Long-Term Follow-Up Care
University of California, San Francisco
NCT05641961
Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients
M.D. Anderson Cancer Center
NCT05101213
A Mindfulness-Based Stress Reduction Program for Improving Mental Health Outcomes for Underserved Cancer Patients in Minnesota
Mayo Clinic
NCT07291011
Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion
M.D. Anderson Cancer Center
NCT06184321
Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events
Mayo Clinic
NCT06640010
Virtual Reality for Symptom Management in Patients Undergoing Hematopoietic Stem Cell Transplantation
Roswell Park Cancer Institute
NCT06798701
Ex Vivo Expansion (ACT-X)
Mayo Clinic
NCT07137312
Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment
Mayo Clinic
NCT07221409
Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial
Mayo Clinic
NCT07089927
Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy
Mayo Clinic
NCT05411523
Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method
M.D. Anderson Cancer Center
NCT05054413
Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic
M.D. Anderson Cancer Center
NCT04500600
An Observational Research Study for Cancer Patients on Immune Checkpoint Inhibitors, DiRECT Study
University of Rochester NCORP Research Base
NCT05364086
NCI COVID-19 in Cancer Patients, NCCAPS Study
National Cancer Institute (NCI)
NCT04387656
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors
M.D. Anderson Cancer Center
NCT04447222
Financial Toxicity in Cancer Patients
M.D. Anderson Cancer Center
NCT04592250
Yoga Program for Improving the Quality of Life in Couples Coping With Cancer
M.D. Anderson Cancer Center
NCT04607590
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 24 |
| Phase 2 | 22 |
| Phase 3 | 12 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Malignant Solid Neoplasm records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Malignant Solid Neoplasm trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Malignant Solid Neoplasm page
177 registered trials, 94 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 94 Malignant Solid Neoplasm trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- M.D. Anderson Cancer Center sponsors the most Malignant Solid Neoplasm trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Malignant Solid Neoplasm condition card totals 177 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.