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Malignant Solid Neoplasm clinical trials
94 of 177 indexed Malignant Solid Neoplasm trials are currently recruiting.
177 US clinical trials · 94 currently recruiting
Malignant Solid Neoplasm is the subject of 177 registered US clinical trials on ClinicalTrials.gov, 94 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 42 of these trials.
The research picture
Malignant Solid Neoplasm has 177 registered US clinical trials, 94 of them open to new participants right now, about 53% of the total.
- 94
- recruiting participants now
- 53%
- of trials open to enrollment
- 14
- in Phase 3–4 (later-stage)
- 42
- top sponsor: M.D. Anderson Cancer Center
Active & Recent Trials
177 total, page 2 of 4
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
Mayo Clinic
NCT03750227
Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer
Mayo Clinic
NCT07477886
Communication Issues in Patient and Provider Discussions of Immunotherapy
Emory University
NCT05873608
Weighted Blanket Use to Reduce Anxiety in Oncology Patients
Ohio State University Comprehensive Cancer Center
NCT06089408
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
Children's Oncology Group
NCT05711667
Investigating Memory and Physical Activity After Cancer Treatment in Survivors of Adolescent and Young Adult Cancers
Mayo Clinic
NCT06880861
Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer
OHSU Knight Cancer Institute
NCT06562777
Intravital Microscopy in Human Solid Tumors
Mayo Clinic
NCT03823144
A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients
University of Michigan Rogel Cancer Center
NCT07291414
Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy
Mayo Clinic
NCT06723041
Transportation for Cancer Care Navigation Tool for Reducing Travel Barriers Among Patients With Solid Tumors Receiving Radiation Therapy
Emory University
NCT06541158
CREATE: Art for Children With Cancer
OHSU Knight Cancer Institute
NCT06342453
Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines
M.D. Anderson Cancer Center
NCT02962661
Cryocompression With or Without Cilostazol for the Prevention of Paclitaxel-induced Neuropathy in Patients With Gynecological Cancers
Emory University
NCT06492070
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
M.D. Anderson Cancer Center
NCT04565665
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
National Cancer Institute (NCI)
NCT06126276
Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell Transplant
M.D. Anderson Cancer Center
NCT04678427
Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting
City of Hope Medical Center
NCT07126301
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Children's Oncology Group
NCT06513962
Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers
City of Hope Medical Center
NCT05722288
Solution-Focused Brief Therapy for Support of Psychological Distress in Adolescent and Young Adult Cancer Survivors
University of Michigan Rogel Cancer Center
NCT06941324
Group Curriculum for Improving Survivorship Outcomes in Adolescent and Young Adult Cancer Survivors
Mayo Clinic
NCT05584449
Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas
Roswell Park Cancer Institute
NCT06202066
Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction
Roswell Park Cancer Institute
NCT06306638
Different Types of Massage Therapy to Reduce Anxiety During Chemotherapy Infusion in Patients With Cancer
City of Hope Medical Center
NCT07184294
A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment
University of Michigan Rogel Cancer Center
NCT07365007
L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance
City of Hope Medical Center
NCT07220447
Data-Driven Strategies for Patient Engagement About Cancer Clinical Trials
University of Southern California
NCT07456436
Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers
Wake Forest University Health Sciences
NCT06709404
Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors
City of Hope Medical Center
NCT06500377
Voices: Messages of Wisdom and Hope in the Face of Illness
Mayo Clinic
NCT07381179
Evaluation of Early Identification of Cognitive Side Effects of Immunotherapy
Masonic Cancer Center, University of Minnesota
NCT06414278
Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma
City of Hope Medical Center
NCT05830058
Mobile App to Help Survivors of Childhood Cancer Navigate Long-Term Follow-Up Care
University of California, San Francisco
NCT05641961
Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients
M.D. Anderson Cancer Center
NCT05101213
A Mindfulness-Based Stress Reduction Program for Improving Mental Health Outcomes for Underserved Cancer Patients in Minnesota
Mayo Clinic
NCT07291011
Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion
M.D. Anderson Cancer Center
NCT06184321
Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events
Mayo Clinic
NCT06640010
Virtual Reality for Symptom Management in Patients Undergoing Hematopoietic Stem Cell Transplantation
Roswell Park Cancer Institute
NCT06798701
Ex Vivo Expansion (ACT-X)
Mayo Clinic
NCT07137312
Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment
Mayo Clinic
NCT07221409
Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial
Mayo Clinic
NCT07089927
Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy
Mayo Clinic
NCT05411523
Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method
M.D. Anderson Cancer Center
NCT05054413
Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic
M.D. Anderson Cancer Center
NCT04500600
An Observational Research Study for Cancer Patients on Immune Checkpoint Inhibitors, DiRECT Study
University of Rochester NCORP Research Base
NCT05364086
NCI COVID-19 in Cancer Patients, NCCAPS Study
National Cancer Institute (NCI)
NCT04387656
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors
M.D. Anderson Cancer Center
NCT04447222
Financial Toxicity in Cancer Patients
M.D. Anderson Cancer Center
NCT04592250
Yoga Program for Improving the Quality of Life in Couples Coping With Cancer
M.D. Anderson Cancer Center
NCT04607590
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 24 |
| Phase 2 | 22 |
| Phase 3 | 12 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Malignant Solid Neoplasm Trial Landscape
177 indexed Malignant Solid Neoplasm studies · 94 recruiting (53%).
Phase mix: 14 late (III/IV) vs 46 early (I/II).
Top sponsor: M.D. Anderson Cancer Center (42 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Malignant Solid Neoplasm?
PlainTrial tracks 177 US clinical trials for Malignant Solid Neoplasm, of which 94 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Malignant Solid Neoplasm?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.