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NCT04494945 · ClinicalTrials.gov registry record · NA

Identifying and Caring for Individuals With Inherited Cancer Syndrome

A NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid System Neoplasm, sponsored by OHSU Knight Cancer Institute.

Recruiting
Registry status
NA
Development phase
27,500
Enrollment target
2
Study locations

NCT04494945: Recruiting NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid System Neoplasm, sponsored by OHSU Knight Cancer Institute.

NCT04494945 is a NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid System Neoplasm that is actively recruiting participants, run by OHSU Knight Cancer Institute. The registered enrollment target is 27,500 participants, above the 985-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (2692% higher). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04494945, a NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid System Neoplasm, is actively recruiting participants, sponsored by OHSU Knight Cancer Institute.

RECRUITING
Registry status
NA
Development phase
27,500 participants
Enrollment target
2
Study locations

Study Summary

This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and ovarian cancer or Lynch syndromes) instead of only testing people whose families are known to be high risk.

Primary Outcome

Determine the costs and effectiveness, specifically Quality Adjusted Life Years (QALYs) associated with genetic screening models based on Cohorts B and C to estimate incremental cost-effectiveness ratio (ICER) and show that the costs per QALY are below the acceptable cost effectiveness threshold.

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Survey Administration
  • OTHER Genetic Testing
  • OTHER Genetic Counseling

Study Locations (2)

Oregon

  • Providence Portland Medical Center - Portland
  • OHSU Knight Cancer Institute - Portland

Trial Details

FieldValue
Enrollment Target 27,500 participants
Start Date 2020-03-09
Est. Completion 2026-03-31
Phase NA
OHSU Knight Cancer Institute

211 total trials

What NCT04494945 shows while recruiting

NCT04494945 is an interventional study that assigns participants to a tested intervention. Its 27,500 participants enrollment target places it among the larger protocols in the corpus, above the 985-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (2692% higher).

The record links to 6 conditions, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 4 interventions - of which Biospecimen Collection is the first listed.

NCT04494945 reports a single indexed study location in Oregon.

Frequently Asked Questions

What is clinical trial NCT04494945 about?

NCT04494945 is a clinical study titled "Identifying and Caring for Individuals With Inherited Cancer Syndrome". This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like heredi...

What is the current status of trial NCT04494945?

This trial is currently recruiting. It is a NA study. The enrollment target is 27,500 participants. The study started on 2020-03-09. Estimated completion is 2026-03-31.

What conditions does trial NCT04494945 study?

This clinical trial studies the following conditions: Malignant Solid Neoplasm, Hematopoietic and Lymphoid System Neoplasm, Lynch Syndrome, Breast Ductal Carcinoma In Situ, Hereditary Neoplastic Syndrome.

What interventions are being tested in trial NCT04494945?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Survey Administration (OTHER), Genetic Testing (OTHER), Genetic Counseling (OTHER).

Who is sponsoring clinical trial NCT04494945?

This trial is sponsored by OHSU Knight Cancer Institute, which has 211 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04494945 being conducted?

This trial has 2 study locations across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Malignant Solid Neoplasm

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04494945's enrollment target sits among peer trials

27,500 2nd of 176 the highest of 176 other Malignant Solid Neoplasm trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Malignant Solid Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

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Source: ClinicalTrials.gov NCT04494945, the US trial registry maintained by the National Library of Medicine. NCT04494945 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.