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NCT05642611 · ClinicalTrials.gov registry record · Phase 3
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy
A Phase 3 study of Malignant Solid Neoplasm, sponsored by SWOG Cancer Research Network.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 777
- Enrollment target
- 20
- Study locations
NCT05642611 is a Phase 3 study of Malignant Solid Neoplasm that is actively recruiting participants, run by SWOG Cancer Research Network. The registered enrollment target is 777 participants, below the 1,136-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (32% lower). The trial reports 20 study locations across 12 states.
The verdict
NCT05642611, a Phase 3 study of Malignant Solid Neoplasm, is actively recruiting participants, sponsored by SWOG Cancer Research Network.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 777 participants
- Enrollment target
- 20
- Study locations
Study Summary
This phase III trial compares the effect of 3 study approaches in preventing chemotherapy-induced peripheral neuropathy: 1) cryocompression, 2) continuous compression, and 3) low cyclic compression. Taxane chemotherapy drugs, such as paclitaxel or docetaxel, can cause a nerve disorder called peripheral neuropathy, which can cause numbness, tingling, or pain in the arms and legs. The 3 study approaches will use a device, called the Paxman Limb Cryocompression System, made of wraps that cool and/or compress the arms and legs. This study may help researchers determine if any of the study approaches are able to prevent taxane chemotherapy from causing peripheral neuropathy.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Quality-of-Life Assessment
- PROCEDURE Cryocompression Therapy
- PROCEDURE Pneumatic Compression Therapy
Study Locations (20)
Kansas
- University of Kansas Cancer Center - Kansas City
- University of Kansas Hospital-Indian Creek Campus - Overland Park
- University of Kansas Hospital-Westwood Cancer Center - Westwood
Michigan
- Henry Ford Macomb Hospital-Clinton Township - Clinton Township
- Henry Ford Hospital - Detroit
- Corewell Health Grand Rapids Hospitals - Butterworth Hospital - Grand Rapids
North Carolina
- CaroMont Regional Medical Center - Gastonia
- Cone Health Cancer Center - Greensboro
- Margaret R Pardee Memorial Hospital - Hendersonville
New Jersey
- The Valley Hospital - Luckow Pavilion - Paramus
- Valley Health System Ridgewood Campus - Ridgewood
New York
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center - New York
- State University of New York Upstate Medical University - Syracuse
Alabama
- University of Alabama at Birmingham Cancer Center - Birmingham
California
- Contra Costa Regional Medical Center - Martinez
Georgia
- Emory University Hospital/Winship Cancer Institute - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 777 participants |
| Start Date | 2023-06-06 |
| Est. Completion | 2031-08-30 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05642611
The ClinicalTrials.gov registry entry for NCT05642611 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 777 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,136-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (32% lower). The listed sponsor is SWOG Cancer Research Network, which has 270 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 4 interventions - of which Biospecimen Collection is the first listed.
NCT05642611 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Kansas, Michigan, North Carolina.
Frequently Asked Questions
What is clinical trial NCT05642611 about?
NCT05642611 is a clinical study titled "Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy". This phase III trial compares the effect of 3 study approaches in preventing chemotherapy-induced peripheral neuropathy: 1) cryocompression, 2) continuous compression, and 3) low cyclic compression. Taxane chemotherapy drugs, such as paclitaxel or docetaxel, can cause a nerve disorder called periphe...
What is the current status of trial NCT05642611?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 777 participants. The study started on 2023-06-06. Estimated completion is 2031-08-30.
What conditions does trial NCT05642611 study?
This clinical trial studies the following conditions: Malignant Solid Neoplasm.
What interventions are being tested in trial NCT05642611?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Quality-of-Life Assessment (OTHER), Cryocompression Therapy (PROCEDURE), Pneumatic Compression Therapy (PROCEDURE).
Who is sponsoring clinical trial NCT05642611?
This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05642611 being conducted?
This trial has 20 study locations across Alabama, California, Georgia, Hawaii, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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