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NCT05178472 · ClinicalTrials.gov registry record · NA

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

A NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, sponsored by Ohio State University Comprehensive Cancer Center.

Recruiting
Registry status
NA
Development phase
200
Enrollment target
1
Study location

NCT05178472 is a NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm that is actively recruiting participants, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 200 participants, below the 1,140-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05178472, a NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, is actively recruiting participants, sponsored by Ohio State University Comprehensive Cancer Center.

RECRUITING
Registry status
NA
Development phase
200 participants
Enrollment target
1
Study location

Study Summary

This clinical trial studies the side effects of stereotactic radiosurgery and how well it works with or without vertebroplasty, separation surgery, or immunotherapy in patients with cancer that is radiation resistant and has spread to the spine (spinal metastases). Spinal metastases are rapidly progressive, have poor prognosis, are extremely difficult to treat, and can effect patient quality of life and overall health. Immunotherapy is a type of standard of care therapy to boost or restore the ability of the immune system to fight cancer. Stereotactic radiosurgery is a type of external radiation therapy that uses special equipment to position the patient and precisely give a single large dose of radiation to a tumor. A vertebroplasty is a procedure used to repair a bone in the spine that has a break caused by cancer, osteoporosis, or trauma. The purpose of this trial is to test different combinations of immunotherapy, stereotactic radiosurgery, and surgery to improve overall survival and quality of life in patients with spinal metastases.

Interventions

  • RADIATION Stereotactic Radiosurgery
  • OTHER Immunotherapy
  • PROCEDURE Vertebroplasty

Study Locations (1)

Ohio

  • Ohio State University Comprehensive Cancer Center - Columbus

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2023-03-27
Est. Completion 2026-12-31
Phase NA

What the Registry Record Tells You About NCT05178472

The ClinicalTrials.gov registry entry for NCT05178472 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,140-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (82% lower). The listed sponsor is Ohio State University Comprehensive Cancer Center, which has 341 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 3 interventions - of which Stereotactic Radiosurgery is the first listed.

NCT05178472 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT05178472 about?

NCT05178472 is a clinical study titled "Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)". This clinical trial studies the side effects of stereotactic radiosurgery and how well it works with or without vertebroplasty, separation surgery, or immunotherapy in patients with cancer that is radiation resistant and has spread to the spine (spinal metastases). Spinal metastases are rapidly prog...

What is the current status of trial NCT05178472?

This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2023-03-27. Estimated completion is 2026-12-31.

What conditions does trial NCT05178472 study?

This clinical trial studies the following conditions: Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm, Metastatic Malignant Neoplasm in the Spine.

What interventions are being tested in trial NCT05178472?

The interventions under investigation include: Stereotactic Radiosurgery (RADIATION), Immunotherapy (OTHER), Vertebroplasty (PROCEDURE).

Who is sponsoring clinical trial NCT05178472?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05178472 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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