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NCT04560673 · ClinicalTrials.gov registry record · Phase 2

Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral Neuropathy

A Phase 2 study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
380
Enrollment target
2
Study locations

NCT04560673 is a Phase 2 study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 380 participants, below the 1,139-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (67% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT04560673, a Phase 2 study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
380 participants
Enrollment target
2
Study locations

Study Summary

This phase II trial investigates how well duloxetine and neurofeedback training work in treating patients with chemotherapy induced peripheral neuropathy. Duloxetine is a type of serotonin and norepinephrine reuptake inhibitor that increases the amount of certain chemicals in the brain that help relieve depression and peripheral neuropathy. Neurofeedback training is a type of therapy that uses an electroencephalograph (EEG) and a computer software program to measure brain wave activity and may help teach patients with peripheral neuropathy (nerve damage) how to change their own brain waves to lower their feelings of neuropathy and help improve their overall quality of life. Giving duloxetine and neurofeedback training may work better in treating peripheral neuropathy caused by chemotherapy compared to duloxetine or neurofeedback training alone.

Interventions

  • OTHER Quality-of-Life Assessment
  • DRUG Duloxetine
  • OTHER Questionnaire Administration
  • BEHAVIORAL Neurofeedback

Study Locations (2)

Texas

  • Harris Health System (LBJ) - Houston
  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 380 participants
Start Date 2020-07-10
Est. Completion 2026-12-31
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT04560673

The ClinicalTrials.gov registry entry for NCT04560673 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 380 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,139-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (67% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 4 interventions - of which Quality-of-Life Assessment is the first listed.

NCT04560673 reports 2 study locations spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT04560673 about?

NCT04560673 is a clinical study titled "Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral Neuropathy". This phase II trial investigates how well duloxetine and neurofeedback training work in treating patients with chemotherapy induced peripheral neuropathy. Duloxetine is a type of serotonin and norepinephrine reuptake inhibitor that increases the amount of certain chemicals in the brain that help rel...

What is the current status of trial NCT04560673?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 380 participants. The study started on 2020-07-10. Estimated completion is 2026-12-31.

What conditions does trial NCT04560673 study?

This clinical trial studies the following conditions: Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm, Chemotherapy-induced Peripheral Neuropathy.

What interventions are being tested in trial NCT04560673?

The interventions under investigation include: Quality-of-Life Assessment (OTHER), Duloxetine (DRUG), Questionnaire Administration (OTHER), Neurofeedback (BEHAVIORAL).

Who is sponsoring clinical trial NCT04560673?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04560673 being conducted?

This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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