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NCT03997370 · ClinicalTrials.gov registry record · Phase 1

Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol

A Phase 1 study of Malignant Solid Neoplasm, sponsored by NRG Oncology.

Recruiting
Registry status
Phase 1
Development phase
350
Enrollment target
20
Study locations

NCT03997370 is a Phase 1 study of Malignant Solid Neoplasm that is actively recruiting participants, run by NRG Oncology. The registered enrollment target is 350 participants, below the 1,139-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (69% lower). The trial reports 20 study locations across 7 states.

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The verdict

NCT03997370, a Phase 1 study of Malignant Solid Neoplasm, is actively recruiting participants, sponsored by NRG Oncology.

RECRUITING
Registry status
Phase 1
Development phase
350 participants
Enrollment target
20
Study locations

Study Summary

This trial studies how well iohexol works in helping doctors calculate the dose of carboplatin given to patients with cancer. Drugs used in chemotherapy, such as carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Understanding how to best calculate the dose of carboplatin given to patients with cancer may help doctors learn how to improve the use of carboplatin in the future.

Conditions Studied

Interventions

  • DRUG Carboplatin
  • PROCEDURE Biospecimen Collection
  • DRUG Iohexol

Study Locations (20)

Colorado

  • UCHealth University of Colorado Hospital - Aurora
  • Poudre Valley Hospital - Fort Collins
  • Cancer Care and Hematology-Fort Collins - Fort Collins
  • UCHealth Greeley Hospital - Greeley
  • Medical Center of the Rockies - Loveland

California

  • UC San Diego Health System - Encinitas - Encinitas
  • UC San Diego Moores Cancer Center - La Jolla
  • University of California Davis Comprehensive Cancer Center - Sacramento
  • UC San Diego Medical Center - Hillcrest - San Diego

Arizona

  • University of Arizona Cancer Center-Orange Grove Campus - Tucson
  • Banner University Medical Center - Tucson - Tucson
  • University of Arizona Cancer Center-North Campus - Tucson

Arkansas

  • Mercy Hospital Fort Smith - Fort Smith
  • CARTI Cancer Center - Little Rock
  • University of Arkansas for Medical Sciences - Little Rock

Connecticut

  • Hartford Hospital - Hartford
  • The Hospital of Central Connecticut - New Britain

Georgia

  • Emory University Hospital Midtown - Atlanta
  • Emory University Hospital/Winship Cancer Institute - Atlanta

District of Columbia

  • Sibley Memorial Hospital - Washington D.C.

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2020-01-15
Est. Completion 2028-02-06
Phase Phase 1

Sponsor

NRG Oncology

64 total trials

What the Registry Record Tells You About NCT03997370

The ClinicalTrials.gov registry entry for NCT03997370 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 350 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,139-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (69% lower). The listed sponsor is NRG Oncology, which has 64 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 3 interventions - of which Carboplatin is the first listed.

NCT03997370 reports 20 study locations spanning 7 distinct geographic areas - top geographies include Colorado, California, Arizona.

Frequently Asked Questions

What is clinical trial NCT03997370 about?

NCT03997370 is a clinical study titled "Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol". This trial studies how well iohexol works in helping doctors calculate the dose of carboplatin given to patients with cancer. Drugs used in chemotherapy, such as carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by ...

What is the current status of trial NCT03997370?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 350 participants. The study started on 2020-01-15. Estimated completion is 2028-02-06.

What conditions does trial NCT03997370 study?

This clinical trial studies the following conditions: Malignant Solid Neoplasm.

What interventions are being tested in trial NCT03997370?

The interventions under investigation include: Carboplatin (DRUG), Biospecimen Collection (PROCEDURE), Iohexol (DRUG).

Who is sponsoring clinical trial NCT03997370?

This trial is sponsored by NRG Oncology, which has 64 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03997370 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.