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ClinicalTrials.gov 51 recruiting now official registry

Leukemia clinical trials

51 of 274 indexed Leukemia trials are currently recruiting.

274 US clinical trials · 51 currently recruiting

Leukemia is the subject of 274 registered US clinical trials on ClinicalTrials.gov, 51 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 193 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 37 of these trials.

The research picture

Leukemia has 274 registered US clinical trials, 51 of them open to new participants right now, about 19% of the total.

51
recruiting participants now
19%
of trials open to enrollment
19
in Phase 3–4 (later-stage)
37
top sponsor: M.D. Anderson Cancer Center
Phase 198Phase 295Phase 318Phase 41

Active & Recent Trials

274 total, page 1 of 6

RECRUITING 15,000 participants

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

UNC Lineberger Comprehensive Cancer Center

NCT01137643

RECRUITING 5,000 participants

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

Children's Oncology Group

NCT00736749

RECRUITING 3,000 participants

Registry of Older Patients With Cancer

UNC Lineberger Comprehensive Cancer Center

NCT01137825

RECRUITING NA 700 participants

HEME Home Transfusion Program

Dana-Farber Cancer Institute

NCT06487247

RECRUITING Phase 3 700 participants

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

Daiichi Sankyo

NCT06578247

RECRUITING 500 participants

Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders

Memorial Sloan Kettering Cancer Center

NCT00582621

RECRUITING NA 500 participants

DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics

UNC Lineberger Comprehensive Cancer Center

NCT06296368

RECRUITING NA 400 participants

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

University of Miami

NCT05745285

RECRUITING NA 356 participants

Mosaic Trial for Stem Cell Transplant Recipients

Northwestern University

NCT06960993

RECRUITING 300 participants

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

Dana-Farber Cancer Institute

NCT04968834

RECRUITING 300 participants

Pre-malignant States to Hematologic Malignancies in Firefighters

Wake Forest University Health Sciences

NCT06870760

RECRUITING Phase 1 171 participants

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Kura Oncology

NCT06001788

RECRUITING Phase 1 170 participants

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

BlossomHill Therapeutics

NCT06501196

RECRUITING Phase 2 160 participants

Cladribine Plus Low Dose Cytarabine (LDAC) Alternating With Decitabine in Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

M.D. Anderson Cancer Center

NCT01515527

RECRUITING NA 140 participants

Effects of Using a Storybook, to Explain Leukemia to Children Versus the Standard Child Life Intervention, on Parental Stress.

Children's Hospital Los Angeles

NCT06360718

RECRUITING Phase 2 130 participants

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

Daiichi Sankyo

NCT06824168

RECRUITING Phase 2 124 participants

Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation

Hannah Choe, MD

NCT07249346

RECRUITING Phase 1 104 participants

CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

University of Chicago

NCT07294677

RECRUITING Early Phase 1 100 participants

Exercise as an Immune Adjuvant for Allogeneic Cell Therapies

University of Arizona

NCT06643221

RECRUITING Early Phase 1 100 participants

Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

Children's Hospital of Philadelphia

NCT02356653

RECRUITING Phase 1 100 participants

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Children's Hospital of Philadelphia

NCT06839456

RECRUITING 100 participants

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

M.D. Anderson Cancer Center

NCT05011045

RECRUITING NA 90 participants

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

Massachusetts General Hospital

NCT05646576

RECRUITING 88 participants

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

National Cancer Institute (NCI)

NCT06856226

RECRUITING NA 88 participants

Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant

University of Nebraska

NCT04898790

RECRUITING Phase 1 82 participants

Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL

Dana-Farber Cancer Institute

NCT03319901

RECRUITING NA 75 participants

Tools for Reducing Inequity in Acute Leukemia (TRIAL): Beta Testing

Dana-Farber Cancer Institute

NCT06907797

RECRUITING NA 70 participants

Spiritual Care Intervention in Adult Patients Diagnosed With Acute Leukemia

University of Chicago

NCT07405424

RECRUITING Phase 1 64 participants

Roginolisib (IOA-244) With Venetoclax and Rituximab for Refractory/Relapsed Chronic Lymphocytic Leukemia (CLL)

Jennifer R. Brown, MD, PhD

NCT06644183

RECRUITING NA 60 participants

A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties

Memorial Sloan Kettering Cancer Center

NCT07052916

RECRUITING Phase 2 60 participants

Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)

M.D. Anderson Cancer Center

NCT05536349

RECRUITING 60 participants

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

National Cancer Institute (NCI)

NCT05237986

RECRUITING Phase 1 52 participants

A Study of Revumenib and Mezigdomide in People With Leukemia

Memorial Sloan Kettering Cancer Center

NCT07356154

RECRUITING NA 40 participants

Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE)

Dana-Farber Cancer Institute

NCT06469307

RECRUITING Phase 1 40 participants

Mosunetuzumab for CLL MRD Clearance

Inhye Ahn

NCT07052695

RECRUITING 40 participants

Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors

M.D. Anderson Cancer Center

NCT01608152

RECRUITING Phase 2 40 participants

A Phase II Study of the Menin Inhibitor Revumenib in Leukemia Associated With Upregulation of HOX Genes

M.D. Anderson Cancer Center

NCT06229912

RECRUITING NA 40 participants

MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

Medical College of Wisconsin

NCT05794880

RECRUITING Phase 1 31 participants

A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax

Jacqueline Garcia, MD

NCT07148180

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

RECRUITING NA 30 participants

I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients

Massachusetts General Hospital

NCT05842603

RECRUITING Phase 1 30 participants

Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia

University of Colorado, Denver

NCT06429449

RECRUITING Phase 1 29 participants

A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

St. Jude Children's Research Hospital

NCT06810583

RECRUITING Phase 2 27 participants

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

M.D. Anderson Cancer Center

NCT05645718

RECRUITING Phase 1 22 participants

Revumenib in Combination With 7+3 + Midostaurin in AML

Richard Stone, MD

NCT06313437

RECRUITING Phase 1 21 participants

Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

Children's Hospital Medical Center, Cincinnati

NCT03826992

RECRUITING 20 participants

Improving Communication and Building a Stronger Medical Home Among Spanish-speaking Families

University of Colorado, Denver

NCT05425992

RECRUITING Phase 1 20 participants

Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies

Stanford University

NCT06408194

RECRUITING Phase 1 15 participants

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

Dana-Farber Cancer Institute

NCT06138587

RECRUITING Phase 1 10 participants

CIML NK Cells With Venetoclax for AML

Dana-Farber Cancer Institute

NCT06152809

Page 1 of 6 Next →

Phase Distribution

PhaseTrial count
Phase 1 98
Phase 2 95
Phase 3 18
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Leukemia Trial Landscape

274 indexed Leukemia studies · 51 recruiting (19%).

Phase mix: 19 late (III/IV) vs 193 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (37 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Leukemia?

PlainTrial tracks 274 US clinical trials for Leukemia, of which 51 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.