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NCT03319901 · ClinicalTrials.gov registry record · Phase 1

Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL

A Phase 1 study of Leukemia, sponsored by Dana-Farber Cancer Institute.

Recruiting
Registry status
Phase 1
Development phase
82
Enrollment target
5
Study locations

NCT03319901 is a Phase 1 study of Leukemia that is actively recruiting participants, run by Dana-Farber Cancer Institute. The registered enrollment target is 82 participants, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (83% lower). The trial reports 5 study locations across 4 states.

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The verdict

NCT03319901, a Phase 1 study of Leukemia, is actively recruiting participants, sponsored by Dana-Farber Cancer Institute.

RECRUITING
Registry status
Phase 1
Development phase
82 participants
Enrollment target
5
Study locations

Study Summary

This research study is studying a medication called Venetoclax and a chemotherapy regimen as a possible treatment for Acute Lymphoblastic Leukemia. The drugs involved in this study are: * Venetoclax * Standard Chemotherapy (which includes cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, 6-mercaptopurine, etoposide, and cytarabine

Conditions Studied

Interventions

  • DRUG Venetoclax
  • DRUG Standard Chemotherapy

Study Locations (5)

Massachusetts

  • Massachusetts General Hospital - Boston
  • Dana Farber Cancer Institute - Boston

Illinois

  • University of Chicago - Chicago

Texas

  • MD Anderson Cancer Center - Houston

Utah

  • Intermountain LDS Hospital - Salt Lake City

Trial Details

FieldValue
Enrollment Target 82 participants
Start Date 2017-10-30
Est. Completion 2027-04-30
Phase Phase 1

Sponsor

Dana-Farber Cancer Institute

781 total trials

What the Registry Record Tells You About NCT03319901

The ClinicalTrials.gov registry entry for NCT03319901 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 82 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (83% lower). The listed sponsor is Dana-Farber Cancer Institute, which has 781 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Leukemia appearing as the primary indexed condition, and to 2 interventions - of which Venetoclax is the first listed.

NCT03319901 reports 5 study locations spanning 4 distinct geographic areas - top geographies include Massachusetts, Illinois, Texas.

Frequently Asked Questions

What is clinical trial NCT03319901 about?

NCT03319901 is a clinical study titled "Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL". This research study is studying a medication called Venetoclax and a chemotherapy regimen as a possible treatment for Acute Lymphoblastic Leukemia. The drugs involved in this study are: * Venetoclax * Standard Chemotherapy (which includes cyclophosphamide, vincristine, doxorubicin, dexamethasone, ...

What is the current status of trial NCT03319901?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 82 participants. The study started on 2017-10-30. Estimated completion is 2027-04-30.

What conditions does trial NCT03319901 study?

This clinical trial studies the following conditions: Leukemia.

What interventions are being tested in trial NCT03319901?

The interventions under investigation include: Venetoclax (DRUG), Standard Chemotherapy (DRUG).

Who is sponsoring clinical trial NCT03319901?

This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03319901 being conducted?

This trial has 5 study locations across Illinois, Massachusetts, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.