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NCT03826992 · ClinicalTrials.gov registry record · Phase 1

Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

A Phase 1 study of Leukemia, sponsored by Children's Hospital Medical Center, Cincinnati.

Recruiting
Registry status
Phase 1
Development phase
21
Enrollment target
1
Study location

NCT03826992 is a Phase 1 study of Leukemia that is actively recruiting participants, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 21 participants, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03826992, a Phase 1 study of Leukemia, is actively recruiting participants, sponsored by Children's Hospital Medical Center, Cincinnati.

RECRUITING
Registry status
Phase 1
Development phase
21 participants
Enrollment target
1
Study location

Study Summary

This study evaluates the safety and tolerability of combining venetoclax with Vyxeos (CPX-351) in pediatric and young adult patients with acute leukemia that has come back or not responded to treatment.

Conditions Studied

Interventions

  • DRUG Venetoclax
  • DRUG Vyxeos

Study Locations (1)

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2018-12-27
Est. Completion 2028-01
Phase Phase 1

What the Registry Record Tells You About NCT03826992

The ClinicalTrials.gov registry entry for NCT03826992 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (96% lower). The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Leukemia appearing as the primary indexed condition, and to 2 interventions - of which Venetoclax is the first listed.

NCT03826992 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT03826992 about?

NCT03826992 is a clinical study titled "Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia". This study evaluates the safety and tolerability of combining venetoclax with Vyxeos (CPX-351) in pediatric and young adult patients with acute leukemia that has come back or not responded to treatment.

What is the current status of trial NCT03826992?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2018-12-27. Estimated completion is 2028-01.

What conditions does trial NCT03826992 study?

This clinical trial studies the following conditions: Leukemia.

What interventions are being tested in trial NCT03826992?

The interventions under investigation include: Venetoclax (DRUG), Vyxeos (DRUG).

Who is sponsoring clinical trial NCT03826992?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03826992 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.