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ClinicalTrials.gov 16 recruiting now early-phase tilt

Kidney Transplant: early-phase trial registry

16 of 31 indexed Kidney Transplant trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #495 of 28,707 conditions by registered trial count.

31 US clinical trials · 16 currently recruiting · #495 of 28,707 conditions by registered trial count

Kidney Transplant: 31 US clinical trials tracked, 16 recruiting.

Kidney Transplant is the subject of 31 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 6 of these trials.

Enrollment posture brief

Registry condition kidney-transplant

OPEN 16 | RECR 52% | LATE 7 | EARLY 12 | RANK #495 | SPON 6

Nearest open-share peer: Cutaneous Melanoma (52% recruiting · 31 trials)

Alcohol Use Disorder71%Kidney Transplant (this)52%Chronic Graft Versus Host Di48.4%Anaplastic Astrocytoma41.9%Aortic Valve Stenosis41.9%
Open-enrollment share among volume-matched conditions near Kidney Transplant

Kidney Transplant lists 16 open slots (52% of 31 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Kidney Transplant on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Kidney Transplant is recruiting above its size-band peers.

    16 of 31 indexed trials (51.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Kidney Transplant research.

    National Institute of Allergy and Infectious Diseases (NIAID) accounts for 6 of 31 trials (19.4%). 24 distinct sponsors appear on at least one study for this condition label.

  3. Most Kidney Transplant trials plan to enrol fewer than 100 people.

    Median target enrolment is 62 among the 31 trials that report a genuine target (sentinel values excluded). 19 of those (61.3%) plan for fewer than 100 participants.

  4. Kidney Transplant splits between interventional and observational designs.

    21 interventional and 10 observational studies make up this index (67.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 26Phase 32Phase 45

Open and recent trials

31 total, page 1 of 1

RECRUITING 50,000 participants

The KidneyCARE (Community Access to Research Equity) Study

Tufts Medical Center

NCT05497518

RECRUITING Phase 2 800 participants

Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05917522

RECRUITING Phase 3 450 participants

Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

Alexion Pharmaceuticals

NCT06830798

RECRUITING 400 participants

A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

Devyser

NCT07006831

RECRUITING Phase 4 264 participants

Empagliflozin Treatment in Kidney Transplant Recipients

VA Office of Research and Development

NCT06013865

RECRUITING Phase 2 200 participants

Advancing Transplantation Outcomes in Children

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06055608

RECRUITING Phase 2 180 participants

Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (IMPROVE TRIAL)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06919003

RECRUITING NA 86 participants

Social Support Counseling Intervention for Kidney Transplant Candidates

Hennepin Healthcare Research Institute

NCT06147076

RECRUITING 80 participants

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

Brigham and Women's Hospital

NCT07222683

RECRUITING 75 participants

Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)

Mayo Clinic

NCT06752577

RECRUITING NA 60 participants

Feasibility and Plausible Effectiveness of a Lifestyle Intervention in Kidney Transplant Recipients (HEAL)

University of Kansas Medical Center

NCT06640179

RECRUITING Phase 4 20 participants

Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

Travere Therapeutics

NCT07219121

RECRUITING Phase 1 20 participants

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06056102

RECRUITING Phase 1 15 participants

Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor

Jeffrey Veale, MD

NCT03707262

RECRUITING Phase 1 12 participants

Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients

Mayo Clinic

NCT05456243

RECRUITING Phase 3 10 participants

An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

Vertex Pharmaceuticals Incorporated

NCT06832410

ACTIVE NOT RECRUITING 177 participants

Pro-active Genetic Testing in Kidney Transplant Patients

Mayo Clinic

NCT05298904

ACTIVE NOT RECRUITING 140 participants

Microbiome and Immunosuppression: The Mission Study

The University of Texas Medical Branch, Galveston

NCT04953715

ACTIVE NOT RECRUITING Phase 1 50 participants

TRT as an Adjunctive ERAS Therapy in ESRD Patients Undergoing Kidney Transplantation

University of California, Los Angeles

NCT07287800

ACTIVE NOT RECRUITING Phase 4 30 participants

Immunogenicity of HPV Vaccine in Transplant Recipients.

Medical College of Wisconsin

NCT05557370

ACTIVE NOT RECRUITING Phase 1 28 participants

Allogeneic Regulatory Dendritic Cell (DCreg) Renal Study

Angus W. Thomson PhD DSc

NCT03726307

COMPLETED 3,175 participants

A Study of Factors That Affect Long-Term Kidney Transplant Function

University of Minnesota

NCT00270712

COMPLETED 307 participants

Proteogenomic Biomarker Panels in a Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT01289717

COMPLETED 180 participants

Natural History Study of Azathioprine Adherence

Thomas E. Nivens, MD

NCT00143910

COMPLETED Phase 2 62 participants

Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine

University of Florida

NCT03527238

COMPLETED Phase 2 40 participants

Sotagliflozin Safety and Tolerability Among Renal Transplant Recipients

Martina McGrath, MD

NCT05405556

COMPLETED Phase 4 36 participants

Dosing Strategies for de Novo Once-daily Extended Release Tacrolimus (LCPT) in Kidney Transplant Recipients

Temple University

NCT03713645

COMPLETED 20 participants

Continuous Glucose Monitoring for Post-kidney Transplantation in Pre-existing Type 2 Diabetes

The Cleveland Clinic

NCT07271433

COMPLETED Phase 2 15 participants

COVID Protection After Transplant - Sanofi GSK (CPAT-SG) Study

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05518487

COMPLETED Early Phase 1 9 participants

A Pilot Study Using Autologous Regulatory T Cell Infusion Zortress (Everolimus) in Renal Transplant Recipients

Roberto Gedaly

NCT03284242

COMPLETED Phase 4 8 participants

Pharmacokinetic Study of Tacrolimus and Mycophenolate Mofetil in Kidney Transplant Recipients With Hyperkalemia Receiving Patiromer

The Rogosin Institute

NCT03229265

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 6
Phase 3 2
Phase 4 5

Named interventions

Most-linked intervention names on Kidney Transplant records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Treg Drug
1 trials
Tacrolimus Extended Release Oral Tablet [Envarsus] 0.13mg/kg/day initiated within post-operative day 3 after kidney transplant Drug
1 trials
Sanofi-GSK monovalent (B.1.351) CoV2 preS dTM-AS03 COVID-19 vaccine Biological
1 trials
PPM-based Computation Assisted Drug Dosing Other
1 trials
eGFR reporting Diagnostic test
1 trials
Testosterone Replacement Therapy Drug
1 trials
Human Papilloma Virus vaccine (GARDASIL 9) Biological
1 trials
Genetic Health Screen Panel Diagnostic test
1 trials

US sites by state

Facility locations filed on Kidney Transplant trials. A trial with sites in several states counts in each.

California 10 trials
Pennsylvania 9 trials
Minnesota 7 trials
Massachusetts 6 trials
Illinois 6 trials
Wisconsin 5 trials
Ohio 5 trials
New York 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Kidney Transplant page

31 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Kidney Transplant condition card totals 31 registered trials; most-linked intervention Treg; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.