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ClinicalTrials.gov 16 recruiting now official registry

Kidney Transplant clinical trials

Every US clinical trial registered for Kidney Transplant — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

31 US clinical trials · 16 currently recruiting

The research picture

Kidney Transplant has 31 registered US clinical trials, 16 of them open to new participants right now — about 52% of the total.

16
recruiting participants now
52%
of trials open to enrollment
7
in Phase 3–4 (later-stage)
6
top sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 50,000 participants

The KidneyCARE (Community Access to Research Equity) Study

Tufts Medical Center

NCT05497518

RECRUITING Phase 2 800 participants

Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05917522

RECRUITING Phase 3 450 participants

Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

Alexion Pharmaceuticals

NCT06830798

RECRUITING 400 participants

A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

Devyser

NCT07006831

RECRUITING Phase 4 264 participants

Empagliflozin Treatment in Kidney Transplant Recipients

VA Office of Research and Development

NCT06013865

RECRUITING Phase 2 200 participants

Advancing Transplantation Outcomes in Children

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06055608

RECRUITING Phase 2 180 participants

Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (IMPROVE TRIAL)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06919003

RECRUITING NA 86 participants

Social Support Counseling Intervention for Kidney Transplant Candidates

Hennepin Healthcare Research Institute

NCT06147076

RECRUITING 80 participants

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

Brigham and Women's Hospital

NCT07222683

RECRUITING 75 participants

Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)

Mayo Clinic

NCT06752577

RECRUITING NA 60 participants

Feasibility and Plausible Effectiveness of a Lifestyle Intervention in Kidney Transplant Recipients (HEAL)

University of Kansas Medical Center

NCT06640179

RECRUITING Phase 4 20 participants

Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

Travere Therapeutics

NCT07219121

RECRUITING Phase 1 20 participants

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06056102

RECRUITING Phase 1 15 participants

Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor

Jeffrey Veale, MD

NCT03707262

RECRUITING Phase 1 12 participants

Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients

Mayo Clinic

NCT05456243

RECRUITING Phase 3 10 participants

An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

Vertex Pharmaceuticals Incorporated

NCT06832410

ACTIVE NOT RECRUITING 177 participants

Pro-active Genetic Testing in Kidney Transplant Patients

Mayo Clinic

NCT05298904

ACTIVE NOT RECRUITING 140 participants

Microbiome and Immunosuppression: The Mission Study

The University of Texas Medical Branch, Galveston

NCT04953715

ACTIVE NOT RECRUITING Phase 1 50 participants

TRT as an Adjunctive ERAS Therapy in ESRD Patients Undergoing Kidney Transplantation

University of California, Los Angeles

NCT07287800

ACTIVE NOT RECRUITING Phase 4 30 participants

Immunogenicity of HPV Vaccine in Transplant Recipients.

Medical College of Wisconsin

NCT05557370

ACTIVE NOT RECRUITING Phase 1 28 participants

Allogeneic Regulatory Dendritic Cell (DCreg) Renal Study

Angus W. Thomson PhD DSc

NCT03726307

COMPLETED 3,175 participants

A Study of Factors That Affect Long-Term Kidney Transplant Function

University of Minnesota

NCT00270712

COMPLETED 307 participants

Proteogenomic Biomarker Panels in a Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT01289717

COMPLETED 180 participants

Natural History Study of Azathioprine Adherence

Thomas E. Nivens, MD

NCT00143910

COMPLETED Phase 2 62 participants

Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine

University of Florida

NCT03527238

COMPLETED Phase 2 40 participants

Sotagliflozin Safety and Tolerability Among Renal Transplant Recipients

Martina McGrath, MD

NCT05405556

COMPLETED Phase 4 36 participants

Dosing Strategies for de Novo Once-daily Extended Release Tacrolimus (LCPT) in Kidney Transplant Recipients

Temple University

NCT03713645

COMPLETED 20 participants

Continuous Glucose Monitoring for Post-kidney Transplantation in Pre-existing Type 2 Diabetes

The Cleveland Clinic

NCT07271433

COMPLETED Phase 2 15 participants

COVID Protection After Transplant - Sanofi GSK (CPAT-SG) Study

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05518487

COMPLETED Early Phase 1 9 participants

A Pilot Study Using Autologous Regulatory T Cell Infusion Zortress (Everolimus) in Renal Transplant Recipients

Roberto Gedaly

NCT03284242

COMPLETED Phase 4 8 participants

Pharmacokinetic Study of Tacrolimus and Mycophenolate Mofetil in Kidney Transplant Recipients With Hyperkalemia Receiving Patiromer

The Rogosin Institute

NCT03229265

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 6
Phase 3 2
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Kidney Transplant Trial Landscape

ClinicalTrials.gov lists 31 US studies indexed under Kidney Transplant, and 16 of those are currently open to recruitment — roughly 52% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Kidney Transplant shows 7 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Kidney Transplant is led by National Institute of Allergy and Infectious Diseases (NIAID) with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 31 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Kidney Transplant?

PlainTrial tracks 31 US clinical trials for Kidney Transplant, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Kidney Transplant?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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