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An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant
NCT06832410 · View on ClinicalTrials.gov ↗
Study Summary
This study will evaluate the efficacy, safety, and tolerability of VX-880 in participants with Type 1 Diabetes (TID) with a kidney transplant.
Conditions Studied
Interventions
- BIOLOGICAL Biological/Vaccine
Study Locations (7)
Other
- Toronto General Hospital - Endocrinology — Toronto
- Vancouver General Hospital - Gordon and Leslie Diamond Health Care Centre — Vancouver
- King Abdullah International Medical Research Center (KAIMRC) - Riyadh - Endocrinology — Riyadh
- King Faisal Specialist Hospital & Research Centre - Riyadh - Endocrinology — Riyadh
Pennsylvania
- Perelman Center for Advanced Medicine - Endocrinology — Philadelphia
- Montefiore Clinical and Translational Research Center - Endocrinology — Pittsburgh
Wisconsin
- UW University Hospital - Endocrinology — Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-03-31 |
| Est. Completion | 2027-09-17 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06832410
The ClinicalTrials.gov registry entry for NCT06832410 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 82 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Type 1 Diabetes appearing as the primary indexed condition, and to 1 intervention — of which Biological/Vaccine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06832410 reports 7 study locations spanning 3 distinct geographic areas — top geographies include Other, Pennsylvania, Wisconsin. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06832410 about?
NCT06832410 is a clinical study titled "An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant". This study will evaluate the efficacy, safety, and tolerability of VX-880 in participants with Type 1 Diabetes (TID) with a kidney transplant.
What is the current status of trial NCT06832410?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 10 participants. The study started on 2025-03-31. Estimated completion is 2027-09-17.
What conditions does trial NCT06832410 study?
This clinical trial studies the following conditions: Type 1 Diabetes, Kidney Transplant. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06832410?
The interventions under investigation include: Biological/Vaccine (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06832410?
This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 82 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06832410 being conducted?
This trial has 7 study locations across Pennsylvania, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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