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Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine
NCT03527238 · View on ClinicalTrials.gov ↗
Study Summary
Clinical trial applying Phenotypic Precision Medicine (PPM) to tacrolimus dosing in liver and/or kidney transplant recipients to show improvement in maintaining drug trough levels within the target range.
Conditions Studied
Interventions
- DRUG Tacrolimus
- OTHER PPM-based Computation Assisted Drug Dosing
Study Locations (3)
California
- UCLA — Los Angeles
Florida
- UF Health at the University of Florida — Gainesville
Other
- National University of Singapore — Singapore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 62 participants |
| Start Date | 2018-09-21 |
| Est. Completion | 2021-08-31 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03527238
The ClinicalTrials.gov registry entry for NCT03527238 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 62 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,066 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Kidney Transplant appearing as the primary indexed condition, and to 2 interventions — of which Tacrolimus is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03527238 reports 3 study locations spanning 3 distinct geographic areas — top geographies include California, Florida, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03527238 about?
NCT03527238 is a clinical study titled "Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine". Clinical trial applying Phenotypic Precision Medicine (PPM) to tacrolimus dosing in liver and/or kidney transplant recipients to show improvement in maintaining drug trough levels within the target range.
What is the current status of trial NCT03527238?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 62 participants. The study started on 2018-09-21. Estimated completion is 2021-08-31.
What conditions does trial NCT03527238 study?
This clinical trial studies the following conditions: Kidney Transplant, Liver Transplant. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03527238?
The interventions under investigation include: Tacrolimus (DRUG), PPM-based Computation Assisted Drug Dosing (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03527238?
This trial is sponsored by University of Florida, which has 1,066 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03527238 being conducted?
This trial has 3 study locations across California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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