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NCT07219121 · ClinicalTrials.gov registry record · Phase 4
Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis
A Phase 4 study of Kidney Transplant and Focal Segmental Glomerulosclerosis, sponsored by Travere Therapeutics.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 20
- Enrollment target
- 9
- Study locations
NCT07219121: Recruiting Phase 4 study of Kidney Transplant and Focal Segmental Glomerulosclerosis, sponsored by Travere Therapeutics.
NCT07219121 is a Phase 4 study of Kidney Transplant and Focal Segmental Glomerulosclerosis that is actively recruiting participants, run by Travere Therapeutics. The registered enrollment target is 20 participants, below the 1,898-participant average among 30 other Kidney Transplant trials with a reported enrollment target (99% lower). The trial reports 9 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07219121, a Phase 4 study of Kidney Transplant and Focal Segmental Glomerulosclerosis, is actively recruiting participants, sponsored by Travere Therapeutics.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 20 participants
- Enrollment target
- 9
- Study locations
Study Summary
To evaluate the safety and efficacy of sparsentan tablets for the treatment of patients with proteinuria after kidney transplantation with once-daily dosing for 36 weeks.
Primary Outcome
Change from baseline (Day 1) in urinary protein/creatinine ratio (UPCR) to Week 36.
Conditions Studied
Interventions
- DRUG Sparsentan
Study Locations (9)
Texas
- Dallas Nephrology Associates - Dallas
- University of Texas - Galveston
Alabama
- University of Alabama at Birmingham - Birmingham
New York
- Cornell Medical Center - New York
North Carolina
- University of North Carolina Chapel Hill - Morrisville
Ohio
- Ohio State University - Columbus
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Washington
- University of Washington - Seattle
Wisconsin
- University of Wisconsin - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-10-07 |
| Est. Completion | 2027-05 |
| Phase | Phase 4 |
What NCT07219121 shows while recruiting
NCT07219121 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,898-participant average among 30 other Kidney Transplant trials with a reported enrollment target (99% lower).
The record links to 4 conditions, with Kidney Transplant appearing as the primary indexed condition, and to 1 intervention - of which Sparsentan is the first listed.
NCT07219121 lists 9 locations in 8 states (Texas, Alabama, New York).
Frequently Asked Questions
What is clinical trial NCT07219121 about?
NCT07219121 is a clinical study titled "Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis". To evaluate the safety and efficacy of sparsentan tablets for the treatment of patients with proteinuria after kidney transplantation with once-daily dosing for 36 weeks.
What is the current status of trial NCT07219121?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2025-10-07. Estimated completion is 2027-05.
What conditions does trial NCT07219121 study?
This clinical trial studies the following conditions: Kidney Transplant, Focal Segmental Glomerulosclerosis, Proteinuria, Immunoglobulin A (IgA) Nephropathy.
What interventions are being tested in trial NCT07219121?
The interventions under investigation include: Sparsentan (DRUG).
Who is sponsoring clinical trial NCT07219121?
This trial is sponsored by Travere Therapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07219121 being conducted?
This trial has 9 study locations across Alabama, New York, North Carolina, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Kidney Transplant
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07219121's enrollment target sits among peer trials
20 23rd of 30 higher than 6 of 30 other Kidney Transplant trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Kidney Transplant trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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