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NCT06055608 · ClinicalTrials.gov registry record · Phase 2
Advancing Transplantation Outcomes in Children
A Phase 2 study of Kidney Transplant, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Recruiting
- Registry status
- Phase 2
- Development phase
- 200
- Enrollment target
- 20
- Study locations
NCT06055608: Recruiting Phase 2 study of Kidney Transplant, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT06055608 is a Phase 2 study of Kidney Transplant that is actively recruiting participants, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 200 participants, below the 1,892-participant average among 30 other Kidney Transplant trials with a reported enrollment target (89% lower). The trial reports 20 study locations across 16 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06055608, a Phase 2 study of Kidney Transplant, is actively recruiting participants, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 200 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a pediatric kidney transplant study comparing the safety and efficacy of an immunosuppressive regimen of belatacept and sirolimus to tacrolimus and Mycophenolate Mofetil (MMF). Two hundred participants will be randomized (1:1) to one of two groups within 24 hours following the transplant procedure. The duration of the study from time of transplant to the primary endpoint is 12-24 months.
Conditions Studied
Interventions
- DRUG Sirolimus
- DRUG Mycophenolate Mofetil
- BIOLOGICAL Belatacept
- DRUG Tacrolimus (Group1)
- DRUG Anti-Thymocyte Globulin (ATG)
Study Locations (20)
California
- Children's Hospital of Los Angeles (Site #: 71036) - Los Angeles
- Cedars-Sinai Medical Center (Site #: 71026) - Los Angeles
- Mattel Children's Hospital, UCLA (Site #: 71012) - Los Angeles
- UCSD Rady Children's Hospital (Site #: 71037) - San Diego
Pennsylvania
- Children's Hospital of Philadelphia (Site #: 71091) - Philadelphia
- UPMC Children's Hospital of Pittsburgh (Site #: 71008) - Pittsburgh
Alabama
- University of Alabama at Birmingham (Site # 71038) - Birmingham
Colorado
- Children's Hospital of Colorado (Site #: 71019) - Aurora
Delaware
- Nemours Children's Health (Site #: 71042) - Wilmington
District of Columbia
- Children's National Medical Center (Site #: 71039) - Washington D.C.
Illinois
- Ann and Robert H. Lurie Children's Hospital of Chicago (Site #: 71016) - Chicago
Maryland
- Johns Hopkins Children's Center (Site #: 71025) - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2024-05-22 |
| Est. Completion | 2028-06-30 |
| Phase | Phase 2 |
What NCT06055608 shows while recruiting
NCT06055608 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 1,892-participant average among 30 other Kidney Transplant trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Kidney Transplant appearing as the primary indexed condition, and to 5 interventions - of which Sirolimus is the first listed.
NCT06055608 names 20 study sites across 16 states, led by California, Pennsylvania, Alabama.
Frequently Asked Questions
What is clinical trial NCT06055608 about?
NCT06055608 is a clinical study titled "Advancing Transplantation Outcomes in Children". This is a pediatric kidney transplant study comparing the safety and efficacy of an immunosuppressive regimen of belatacept and sirolimus to tacrolimus and Mycophenolate Mofetil (MMF). Two hundred participants will be randomized (1:1) to one of two groups within 24 hours following the transplant pro...
What is the current status of trial NCT06055608?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2024-05-22. Estimated completion is 2028-06-30.
What conditions does trial NCT06055608 study?
This clinical trial studies the following conditions: Kidney Transplant.
What interventions are being tested in trial NCT06055608?
The interventions under investigation include: Sirolimus (DRUG), Mycophenolate Mofetil (DRUG), Belatacept (BIOLOGICAL), Tacrolimus (Group1) (DRUG), Anti-Thymocyte Globulin (ATG) (DRUG).
Who is sponsoring clinical trial NCT06055608?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06055608 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, Delaware, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Kidney Transplant
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06055608's enrollment target sits among peer trials
200 8th of 30 higher than 23 of 30 other Kidney Transplant trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Kidney Transplant trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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