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Ischemic Stroke: early-phase trial registry
30 of 67 indexed Ischemic Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #208 of 28,707 conditions by registered trial count.
67 US clinical trials · 30 currently recruiting · #208 of 28,707 conditions by registered trial count
Ischemic Stroke: 67 US clinical trials tracked, 30 recruiting.
Ischemic Stroke is the subject of 67 registered US clinical trials on ClinicalTrials.gov, 30 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 4 of these trials.
Enrollment posture brief
Registry condition ischemic-stroke
OPEN 30 | RECR 45% | LATE 3 | EARLY 19 | RANK #208 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Food Insecurity (45% recruiting · 38 trials)
Ischemic Stroke lists 30 open slots (45% of 67 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Ischemic Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Ischemic Stroke is recruiting above its size-band peers.
30 of 67 indexed trials (44.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Ischemic Stroke trials is spread across many organizations.
Johns Hopkins University accounts for 4 of 67 trials (6%). 52 distinct sponsors appear on at least one study for this condition label.
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Typical Ischemic Stroke enrolment sits around 83 participants.
Median target enrolment is 83 among the 67 trials that report a genuine target (sentinel values excluded). 35 of those (52.2%) plan for fewer than 100 participants.
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Ischemic Stroke research is mostly interventional.
48 interventional and 19 observational studies make up this index (71.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
67 total, page 1 of 2
Stroke Recovery Initiative - Registry for Stroke Research Studies
University of California, San Francisco
NCT03318432
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
Massachusetts General Hospital
NCT04916210
Transitions of Care for Stroke Patients
Kiwon Lee MD
NCT06011720
StrokeNet Thrombectomy Endovascular Platform
Medical University of South Carolina
NCT06289985
Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders
Cedars-Sinai Medical Center
NCT02910180
CTSN Embolic Protection Trial
Icahn School of Medicine at Mount Sinai
NCT06027788
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
DiaMedica Therapeutics
NCT05065216
Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe
Raul Nogueira
NCT05983757
Augmented Renal Clearance in Neurocritical Care
University of Alberta
NCT07410624
The Recovery in Stroke Using PAP Study
Yale University
NCT04130503
Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke
University of Virginia
NCT06292117
Strategy for Improving Stroke Treatment Response
Translational Sciences
NCT05948566
Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis
University of California, Los Angeles
NCT05518305
Regulating Blood Pressure During Recovery From Intracerebral Hemorrhage and Ischemic Stroke
Yale University
NCT04760717
Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline
Johns Hopkins University
NCT05556395
Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors
Massachusetts General Hospital
NCT07414732
Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial
ProMedica Health System
NCT06949228
EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment
BrainQ Technologies
NCT06386874
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
The Methodist Hospital Research Institute
NCT06286800
External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients
Johns Hopkins University
NCT06899711
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
University of Pennsylvania
NCT04897334
K01 Impacts of Lingual Endurance Exercise
University of Cincinnati
NCT06072924
Verapamil for Neuroprotection in Stroke
Global Neurosciences Institute
NCT03347786
Imaging the Pathogenesis of Cerebral Small Vessel Disease
Johns Hopkins University
NCT05703386
Post-Stroke Sensory Reweighting on Walking and Balance Outcomes
University of Cincinnati
NCT06727097
Wireless Nerve Stimulation Device To Enhance Recovery After Stroke
Baylor Research Institute
NCT04534556
OsciPulse D-dimer Pilot Trial
University of Pennsylvania
NCT06477016
A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke
Mayo Clinic
NCT07291024
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
Johns Hopkins University
NCT07053917
Virtual Reality Based Rehabilitation After Ischemic Stroke
Stony Brook University
NCT06401564
Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
AtriCure
NCT05478304
Sleep for Stroke Management and Recovery Trial
University of Michigan
NCT03812653
A Comparison of Hemorrhagic and Ischemic Strokes Among Blacks and Whites
University of Cincinnati
NCT00642213
Distal Ischemic Stroke Treatment With Adjustable Low-profile Stentriever
Rapid Medical
NCT05152524
Symptomatic Carotid Outcomes Registry
University of Maryland, Baltimore
NCT05300737
Florida Cerebrovascular Disease Biorepository and Genomics Center
Mayo Clinic
NCT05491980
VNS-REHAB At-Home - Post-Market Study for Using the Vivistim System® at Home
MicroTransponder
NCT05691023
A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS)
Gary Steinberg, MD, PhD
NCT04631406
Memantine for Enhanced Stroke Recovery
University of Utah
NCT02144584
A Study of NCS-01 in Patients With Acute Ischemic Stroke
NC Medial Research
NCT03915431
Addressing Sleep Apnea Post-Stroke/TIA
VA Office of Research and Development
NCT04322162
Patient-centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research
Duke University
NCT02146274
Quality Improvement in Stroke Prevention (QUISP)
University of California, San Francisco
NCT00328640
Patent Foramen Ovale in Cryptogenic Stroke Study
Columbia University
NCT00697151
Discharge Educational Strategies for Reduction of Vascular Events
NYU Langone Health
NCT01836354
Investigation of Clot in Ischemic Stroke and Hematoma Evacuation
Penumbra
NCT04693767
The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke
Mercy Health Ohio
NCT03805308
Treatment With Intent to Generate Endovascular Reperfusion
Rapid Medical
NCT03474549
Assess the Penumbra System in the Treatment of Acute Stroke
Penumbra
NCT01429350
The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "EMAGINE" STUDY)
BrainQ Technologies
NCT05044507
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 9 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Ischemic Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Ischemic Stroke trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Ischemic Stroke page
67 registered trials, 30 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 30 Ischemic Stroke trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Johns Hopkins University sponsors the most Ischemic Stroke trials on record, review their full trial history before evaluating a specific study. See Johns Hopkins University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ischemic Stroke condition card totals 67 registered trials; most-linked intervention Aspirin; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.