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Ischemic Stroke
Open-data reference.
67 US clinical trials · 30 currently recruiting
Active & Recent Trials
Stroke Recovery Initiative - Registry for Stroke Research Studies
University of California, San Francis
NCT03318432
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
Massachusetts General Hospital
NCT04916210
Transitions of Care for Stroke Patients
Kiwon Lee MD
NCT06011720
StrokeNet Thrombectomy Endovascular Platform
Medical University of South Carolina
NCT06289985
Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders
Cedars-Sinai Medical Center
NCT02910180
CTSN Embolic Protection Trial
Icahn School of Medicine at Mount Sinai
NCT06027788
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
DiaMedica Therapeutics
NCT05065216
Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe
Raul Nogueira
NCT05983757
Augmented Renal Clearance in Neurocritical Care
University of Alberta
NCT07410624
The Recovery in Stroke Using PAP Study
Yale University
NCT04130503
Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke
University of Virginia
NCT06292117
Strategy for Improving Stroke Treatment Response
Translational Sciences
NCT05948566
Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis
University of California, Los Angeles
NCT05518305
Regulating Blood Pressure During Recovery From Intracerebral Hemorrhage and Ischemic Stroke
Yale University
NCT04760717
Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline
Johns Hopkins University
NCT05556395
Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors
Massachusetts General Hospital
NCT07414732
Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial
ProMedica Health System
NCT06949228
EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment
BrainQ Technologies
NCT06386874
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
The Methodist Hospital Research Institute
NCT06286800
External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients
Johns Hopkins University
NCT06899711
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
University of Pennsylvania
NCT04897334
K01 Impacts of Lingual Endurance Exercise
University of Cincinnati
NCT06072924
Verapamil for Neuroprotection in Stroke
Global Neurosciences Institute
NCT03347786
Imaging the Pathogenesis of Cerebral Small Vessel Disease
Johns Hopkins University
NCT05703386
Post-Stroke Sensory Reweighting on Walking and Balance Outcomes
University of Cincinnati
NCT06727097
Wireless Nerve Stimulation Device To Enhance Recovery After Stroke
Baylor Research Institute
NCT04534556
OsciPulse D-dimer Pilot Trial
University of Pennsylvania
NCT06477016
A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke
Mayo Clinic
NCT07291024
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
Johns Hopkins University
NCT07053917
Virtual Reality Based Rehabilitation After Ischemic Stroke
Stony Brook University
NCT06401564
Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
AtriCure
NCT05478304
Sleep for Stroke Management and Recovery Trial
University of Michigan
NCT03812653
A Comparison of Hemorrhagic and Ischemic Strokes Among Blacks and Whites
University of Cincinnati
NCT00642213
Distal Ischemic Stroke Treatment With Adjustable Low-profile Stentriever
Rapid Medical
NCT05152524
Symptomatic Carotid Outcomes Registry
University of Maryland, Baltimore
NCT05300737
Florida Cerebrovascular Disease Biorepository and Genomics Center
Mayo Clinic
NCT05491980
VNS-REHAB At-Home - Post-Market Study for Using the Vivistim System® at Home
MicroTransponder
NCT05691023
A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS)
Gary Steinberg, MD, PhD
NCT04631406
Memantine for Enhanced Stroke Recovery
University of Utah
NCT02144584
A Study of NCS-01 in Patients With Acute Ischemic Stroke
NC Medial Research
NCT03915431
Addressing Sleep Apnea Post-Stroke/TIA
VA Office of Research and Development
NCT04322162
Patient-centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research
Duke University
NCT02146274
Quality Improvement in Stroke Prevention (QUISP)
University of California, San Francis
NCT00328640
Patent Foramen Ovale in Cryptogenic Stroke Study
Columbia University
NCT00697151
Discharge Educational Strategies for Reduction of Vascular Events
NYU Langone Health
NCT01836354
Investigation of Clot in Ischemic Stroke and Hematoma Evacuation
Penumbra
NCT04693767
The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke
Mercy Health Ohio
NCT03805308
Treatment With Intent to Generate Endovascular Reperfusion
Rapid Medical
NCT03474549
Assess the Penumbra System in the Treatment of Acute Stroke
Penumbra
NCT01429350
The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "EMAGINE" STUDY)
BrainQ Technologies
NCT05044507
Hemodynamic Effects on Cerebral Autoregulation in Acute Stroke
Henry Ford Health System
NCT02056821
A Phase 2b Study of Dalfampridine 10mg Extended Release Tablet in Subjects With Chronic Deficits After Ischemic Stroke
Acorda Therapeutics
NCT01605825
Functional Magnetic Resonance Imaging (fMRI) and Robot-Assisted Practice of Activities of Daily Living
Medical College of Wisconsin
NCT00878085
The Capillary Index Score Trial
Firas Al-Ali
NCT02618031
Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke
Northwell Health
NCT02232022
The PERFusion Use in Stroke Evaluation Study
California Pacific Medical Center Research Institute
NCT01387113
Stroke and CPAP Outcome Study 3
University of Washington
NCT06029959
Mayo Acute Stroke Trial for Enhancing Recovery
Mayo Clinic
NCT00805792
Safety/Feasibility of Autologous Mononuclear Bone Marrow Cells in Stroke Patients
The University of Texas Health Science Center, Houston
NCT00859014
REcurrent Stroke Prevention Through Personalized Education by Clinical Trainers (RESPPECT Trial)
Washington Regional Medical Center
NCT03861494
Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial
ProMedica Health System
NCT05172934
Dietary Nitrate Supplements and Ischemic Stroke Recovery
Wake Forest University Health Sciences
NCT02838901
Combination Anti-Platelet and Anti-Coagulation Treatment After Lysis of Ischemic Stroke Trial (CATALIST)
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00061373
A Study to Evaluate the Effect of Diltiazem on the Pharmacokinetics (PK) of BMS-986141 in Healthy Subjects
Bristol-Myers Squibb
NCT02922452
Assessing the Safety and Effectiveness of a Neurological Thrombectomy Medical Device for Acute Ischemic Stroke
Jacobs institute
NCT05074186
IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion
University of North Carolina, Chapel Hill
NCT00624000
Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke
Abington Memorial Hospital
NCT03352232
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 10 |
| Phase 2 | 9 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Ischemic Stroke Trial Landscape
ClinicalTrials.gov lists 67 US studies indexed under Ischemic Stroke, and 30 of those are currently open to recruitment — roughly 45% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Ischemic Stroke shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 19 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Ischemic Stroke is led by Johns Hopkins University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 67 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Ischemic Stroke?
PlainTrial tracks 67 US clinical trials for Ischemic Stroke, of which 30 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Ischemic Stroke?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.