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The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke
NCT03805308 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of the trial is to establish the effectiveness of IAT (versus medical management) in patients with moderate-large infarcts (NCCT ASPECTS 2-5) at baseline, with adaptive enrichment to better define the upper limit of infarct volume for treatment eligibility. Furthermore, the investigators aim to determine whether certain subgroups of patients with large baseline infarcts will have a greater treatment benefit. Finally, the investigators will assess the agreement of ASPECTS scores between site investigators, the core imaging lab, and automated software.
Conditions Studied
Interventions
- PROCEDURE Intra-arterial Therapy
Study Locations (20)
California
- PIH Health Good Samaritan Hospital and PIH Health Whittier Hospital — Los Angeles
- Pomona Valley Hospital Medical Center — Pomona
- Sutter Institute for Medical Research — Sacramento
- California Pacific Medical Center & Mills Peninsula Medical Center — San Francisco
- Los Robles Hospital and Medical Center — Thousand Oaks
- Providence Saint John's Health Center — Torrance
Florida
- Boca Raton Regional Hospital Inc. — Boca Raton
- University of Miami — Coral Gables
- Tenet Health Systems (Delray Medical Center, St. Mary's Medical Center, Palmetto General Hospital) — Delray Beach
- Orlando Health Inc. — Orlando
- University of South Florida — Tampa
Illinois
- The University of Chicago — Chicago
- Northwestern University — Evanston
- AMITA Resurrection Medical Center and AMITA Saint Joseph Medical Center — Lisle
- Central DuPage Hospital Association d/b/a Northwestern Medicine Central DuPage Hospital — Winfield
Indiana
- Lutheran Medical Group — Fort Wayne
- Munster Medical Research Foundation — Munster
Arkansas
- Baptist Health Center for Clinical Research — Little Rock
Georgia
- Wellstar Health System, Inc. — Marietta
Iowa
- The University of Iowa — Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2019-07-16 |
| Est. Completion | 2023-11-18 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03805308
The ClinicalTrials.gov registry entry for NCT03805308 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mercy Health Ohio, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Ischemic Stroke appearing as the primary indexed condition, and to 1 intervention — of which Intra-arterial Therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03805308 reports 20 study locations spanning 7 distinct geographic areas — top geographies include California, Florida, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03805308 about?
NCT03805308 is a clinical study titled "The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke". The primary objective of the trial is to establish the effectiveness of IAT (versus medical management) in patients with moderate-large infarcts (NCCT ASPECTS 2-5) at baseline, with adaptive enrichment to better define the upper limit of infarct volume for treatment eligibility. Furthermore, the inv...
What is the current status of trial NCT03805308?
This trial is currently completed. It is a NA study. The enrollment target is 300 participants. The study started on 2019-07-16. Estimated completion is 2023-11-18.
What conditions does trial NCT03805308 study?
This clinical trial studies the following conditions: Ischemic Stroke. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03805308?
The interventions under investigation include: Intra-arterial Therapy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03805308?
This trial is sponsored by Mercy Health Ohio, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03805308 being conducted?
This trial has 20 study locations across Arkansas, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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