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NCT03805308 · ClinicalTrials.gov registry record · NA
The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke
A NA study of Ischemic Stroke, sponsored by Mercy Health Ohio.
- Completed
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 20
- Study locations
NCT03805308: Completed NA study of Ischemic Stroke, sponsored by Mercy Health Ohio.
NCT03805308 is a NA study of Ischemic Stroke that has completed, run by Mercy Health Ohio. The registered enrollment target is 300 participants, below the 1,459-participant average among 66 other Ischemic Stroke trials with a reported enrollment target (79% lower). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03805308, a NA study of Ischemic Stroke, has completed, sponsored by Mercy Health Ohio.
- COMPLETED
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 20
- Study locations
Study Summary
The primary objective of the trial is to establish the effectiveness of IAT (versus medical management) in patients with moderate-large infarcts (NCCT ASPECTS 2-5) at baseline, with adaptive enrichment to better define the upper limit of infarct volume for treatment eligibility. Furthermore, the investigators aim to determine whether certain subgroups of patients with large baseline infarcts will have a greater treatment benefit. Finally, the investigators will assess the agreement of ASPECTS scores between site investigators, the core imaging lab, and automated software.
Primary Outcome
Scale used for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability. Scale ranges from 0-6 where 0 represents no symptoms and 6 represents death. 0 = No symptoms at all. 1. = No significant disability despite symptoms; able to carry out all usual duties and activities. 2. = Slight disability; unable to carry out all previous activities but able to look after own affairs without assistance. 3. =
Conditions Studied
Interventions
- PROCEDURE Intra-arterial Therapy
Study Locations (20)
California
- PIH Health Good Samaritan Hospital and PIH Health Whittier Hospital - Los Angeles
- Pomona Valley Hospital Medical Center - Pomona
- Sutter Institute for Medical Research - Sacramento
- California Pacific Medical Center & Mills Peninsula Medical Center - San Francisco
- Los Robles Hospital and Medical Center - Thousand Oaks
- Providence Saint John's Health Center - Torrance
Florida
- Boca Raton Regional Hospital Inc. - Boca Raton
- University of Miami - Coral Gables
- Tenet Health Systems (Delray Medical Center, St. Mary's Medical Center, Palmetto General Hospital) - Delray Beach
- Orlando Health Inc. - Orlando
- University of South Florida - Tampa
Illinois
- The University of Chicago - Chicago
- Northwestern University - Evanston
- AMITA Resurrection Medical Center and AMITA Saint Joseph Medical Center - Lisle
- Central DuPage Hospital Association d/b/a Northwestern Medicine Central DuPage Hospital - Winfield
Indiana
- Lutheran Medical Group - Fort Wayne
- Munster Medical Research Foundation - Munster
Arkansas
- Baptist Health Center for Clinical Research - Little Rock
Georgia
- Wellstar Health System, Inc. - Marietta
Iowa
- The University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2019-07-16 |
| Est. Completion | 2023-11-18 |
| Phase | NA |
What the finished NCT03805308 record still lists
NCT03805308 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 1,459-participant average among 66 other Ischemic Stroke trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Ischemic Stroke appearing as the primary indexed condition, and to 1 intervention - of which Intra-arterial Therapy is the first listed.
NCT03805308 names 20 study sites across 7 states, led by California, Florida, Illinois.
Frequently Asked Questions
What is clinical trial NCT03805308 about?
NCT03805308 is a clinical study titled "The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke". The primary objective of the trial is to establish the effectiveness of IAT (versus medical management) in patients with moderate-large infarcts (NCCT ASPECTS 2-5) at baseline, with adaptive enrichment to better define the upper limit of infarct volume for treatment eligibility. Furthermore, the inv...
What is the current status of trial NCT03805308?
This trial is currently completed. It is a NA study. The enrollment target is 300 participants. The study started on 2019-07-16. Estimated completion is 2023-11-18.
What conditions does trial NCT03805308 study?
This clinical trial studies the following conditions: Ischemic Stroke.
What interventions are being tested in trial NCT03805308?
The interventions under investigation include: Intra-arterial Therapy (PROCEDURE).
Who is sponsoring clinical trial NCT03805308?
This trial is sponsored by Mercy Health Ohio, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03805308 being conducted?
This trial has 20 study locations across Arkansas, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03805308's enrollment target sits among peer trials
300 20th of 66 higher than 46 of 66 other Ischemic Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ischemic Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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