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NCT03347786 · ClinicalTrials.gov registry record · Phase 1
Verapamil for Neuroprotection in Stroke
A Phase 1 study of Ischemic Stroke, sponsored by Global Neurosciences Institute.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
- 3
- Study locations
NCT03347786: Recruiting Phase 1 study of Ischemic Stroke, sponsored by Global Neurosciences Institute.
NCT03347786 is a Phase 1 study of Ischemic Stroke that is actively recruiting participants, run by Global Neurosciences Institute. The registered enrollment target is 60 participants, below the 1,463-participant average among 66 other Ischemic Stroke trials with a reported enrollment target (96% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03347786, a Phase 1 study of Ischemic Stroke, is actively recruiting participants, sponsored by Global Neurosciences Institute.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this research study is to test an experimental procedure called intra-arterial delivery of verapamil in patients diagnosed with acute ischemic stroke. This study investigates the safety of intra-arterial delivery of verapamil, a drug used to treat vasospasm (spasm of a blood vessel), and how it affects recovery from stroke. Recruitment is limited to patients that have received mechanical thrombectomy as standard of care.
Primary Outcome
Bleeding Complications including: symptomatic intracerebral hemorrhage (sICH), and Hemorrhagic Transformation (HT)
Conditions Studied
Interventions
- DRUG 10 mg Intra-arterial Verapamil
- DRUG 20 mg Intra-arterial Verapamil
Study Locations (3)
Pennsylvania
- St Mary Medical Center - Langhorne
- Crozer Chester Medical Center - Upland
New Jersey
- AtlantiCare Regional Medical Center - Atlantic City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2017-04-20 |
| Est. Completion | 2026-12 |
| Phase | Phase 1 |
What NCT03347786 shows while recruiting
NCT03347786 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,463-participant average among 66 other Ischemic Stroke trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Ischemic Stroke appearing as the primary indexed condition, and to 2 interventions - of which 10 mg Intra-arterial Verapamil is the first listed.
NCT03347786 reports a single indexed study location in Pennsylvania, New Jersey.
Frequently Asked Questions
What is clinical trial NCT03347786 about?
NCT03347786 is a clinical study titled "Verapamil for Neuroprotection in Stroke". The purpose of this research study is to test an experimental procedure called intra-arterial delivery of verapamil in patients diagnosed with acute ischemic stroke. This study investigates the safety of intra-arterial delivery of verapamil, a drug used to treat vasospasm (spasm of a blood vessel), ...
What is the current status of trial NCT03347786?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2017-04-20. Estimated completion is 2026-12.
What conditions does trial NCT03347786 study?
This clinical trial studies the following conditions: Ischemic Stroke.
What interventions are being tested in trial NCT03347786?
The interventions under investigation include: 10 mg Intra-arterial Verapamil (DRUG), 20 mg Intra-arterial Verapamil (DRUG).
Who is sponsoring clinical trial NCT03347786?
This trial is sponsored by Global Neurosciences Institute, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03347786 being conducted?
This trial has 3 study locations across New Jersey, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ischemic Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03347786's enrollment target sits among peer trials
60 41st of 66 higher than 26 of 66 other Ischemic Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ischemic Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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