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NCT05300737 · ClinicalTrials.gov registry record

Symptomatic Carotid Outcomes Registry

A clinical trial of Ischemic Stroke and Carotid Stenosis, sponsored by University of Maryland, Baltimore.

Active
Registry status
114
Enrollment target
18
Study locations

NCT05300737: Active study of Ischemic Stroke and Carotid Stenosis, sponsored by University of Maryland, Baltimore.

NCT05300737 is a study of Ischemic Stroke and Carotid Stenosis that is active but no longer recruiting, run by University of Maryland, Baltimore. The registered enrollment target is 114 participants, below the 1,462-participant average among 66 other Ischemic Stroke trials with a reported enrollment target (92% lower). The trial reports 18 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05300737, a study of Ischemic Stroke and Carotid Stenosis, is active but no longer recruiting, sponsored by University of Maryland, Baltimore.

ACTIVE NOT RECRUITING
Registry status
114 participants
Enrollment target
18
Study locations

Study Summary

The purpose of this study is to build upon trials done over 30 years ago, which did not include statins, new antiplatelet agents, and newer antihypertensive medications. Since the landmark trials (NASCET, ECST), there have been new developments in medical stroke prevention, which creates a gap in knowledge. The aim of this study is to evaluate that clinical care with Intensive Medical Therapy (IMT) alone, the one year stroke rate in patients with symptomatic carotid stenosis and low risk clinical features will be \<5%.

Primary Outcome

ipsilateral to carotid stenosis, with radiologic confirmation

Interventions

  • OTHER intensive medical therapy

Study Locations (18)

Illinois

  • Northwestern Memorial Hospital - Chicago
  • Rush Medical Center - Chicago

Massachusetts

  • Baystate Medical Center - Springfield
  • University of Massachusetts Medical Center - Worcester

Alberta

  • Calgary Health Sciences Center - Calgary
  • University of Alberta - Edmonton

Ontario

  • Northern Ontario School of Medicine - Greater Sudbury
  • Western University/London Health Sciences Center - London

Connecticut

  • Hartford Hospital - Hartford

Georgia

  • Emory University Hospital - Atlanta

Iowa

  • University of Iowa - Iowa City

Maryland

  • University of Maryland Medical Center - Baltimore

Trial Details

FieldValue
Enrollment Target 114 participants
Start Date 2022-08-01
Est. Completion 2026-12
University of Maryland, Baltimore

560 total trials

What the registry record for NCT05300737 still lists

NCT05300737 is an observational study that tracks outcomes without assigning an intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap, below the 1,462-participant average among 66 other Ischemic Stroke trials with a reported enrollment target (92% lower).

The record links to 3 conditions, with Ischemic Stroke appearing as the primary indexed condition, and to 1 intervention - of which intensive medical therapy is the first listed.

NCT05300737 lists 18 locations in 14 states (Illinois, Massachusetts, Alberta).

Frequently Asked Questions

What is clinical trial NCT05300737 about?

NCT05300737 is a clinical study titled "Symptomatic Carotid Outcomes Registry". The purpose of this study is to build upon trials done over 30 years ago, which did not include statins, new antiplatelet agents, and newer antihypertensive medications. Since the landmark trials (NASCET, ECST), there have been new developments in medical stroke prevention, which creates a gap in kn...

What is the current status of trial NCT05300737?

This trial is currently active not recruiting. The enrollment target is 114 participants. The study started on 2022-08-01. Estimated completion is 2026-12.

What conditions does trial NCT05300737 study?

This clinical trial studies the following conditions: Ischemic Stroke, Carotid Stenosis, Transient Ischemic Attack.

What interventions are being tested in trial NCT05300737?

The interventions under investigation include: intensive medical therapy (OTHER).

Who is sponsoring clinical trial NCT05300737?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05300737 being conducted?

This trial has 18 study locations across Connecticut, Georgia, Illinois, Iowa, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Ischemic Stroke

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05300737's enrollment target sits among peer trials

114 30th of 66 higher than 37 of 66 other Ischemic Stroke trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Ischemic Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05300737, the US trial registry maintained by the National Library of Medicine. NCT05300737 (mid enrollment · multi site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.