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ClinicalTrials.gov 30 recruiting now early-phase tilt

Ischemic Stroke: early-phase trial registry

30 of 67 indexed Ischemic Stroke trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #208 of 28,707 conditions by registered trial count.

67 US clinical trials · 30 currently recruiting · #208 of 28,707 conditions by registered trial count

Ischemic Stroke: 67 US clinical trials tracked, 30 recruiting.

Ischemic Stroke is the subject of 67 registered US clinical trials on ClinicalTrials.gov, 30 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 4 of these trials.

Enrollment posture brief

Registry condition ischemic-stroke

OPEN 30 | RECR 45% | LATE 3 | EARLY 19 | RANK #208 | SPON 4

Nearest open-share peer: Food Insecurity (45% recruiting · 38 trials)

Brain Metastases60.3%Ischemic Stroke (this)45%Parenting40.3%Alcoholism16.4%Acne Vulgaris2.9%
Open-enrollment share among volume-matched conditions near Ischemic Stroke

Ischemic Stroke lists 30 open slots (45% of 67 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ischemic Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ischemic Stroke is recruiting above its size-band peers.

    30 of 67 indexed trials (44.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Ischemic Stroke trials is spread across many organizations.

    Johns Hopkins University accounts for 4 of 67 trials (6%). 52 distinct sponsors appear on at least one study for this condition label.

  3. Typical Ischemic Stroke enrolment sits around 83 participants.

    Median target enrolment is 83 among the 67 trials that report a genuine target (sentinel values excluded). 35 of those (52.2%) plan for fewer than 100 participants.

  4. Ischemic Stroke research is mostly interventional.

    48 interventional and 19 observational studies make up this index (71.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 29Phase 43

Open and recent trials

67 total, page 2 of 2

COMPLETED 88 participants

Hemodynamic Effects on Cerebral Autoregulation in Acute Stroke

Henry Ford Health System

NCT02056821

COMPLETED Phase 2 83 participants

A Phase 2b Study of Dalfampridine 10mg Extended Release Tablet in Subjects With Chronic Deficits After Ischemic Stroke

Acorda Therapeutics

NCT01605825

COMPLETED Phase 1 61 participants

Functional Magnetic Resonance Imaging (fMRI) and Robot-Assisted Practice of Activities of Daily Living

Medical College of Wisconsin

NCT00878085

COMPLETED Phase 1 57 participants

The Capillary Index Score Trial

Firas Al-Ali

NCT02618031

COMPLETED NA 53 participants

Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke

Northwell Health

NCT02232022

COMPLETED 48 participants

The PERFusion Use in Stroke Evaluation Study

California Pacific Medical Center Research Institute

NCT01387113

COMPLETED NA 36 participants

Stroke and CPAP Outcome Study 3

University of Washington

NCT06029959

COMPLETED Phase 2 33 participants

Mayo Acute Stroke Trial for Enhancing Recovery

Mayo Clinic

NCT00805792

COMPLETED Phase 1 25 participants

Safety/Feasibility of Autologous Mononuclear Bone Marrow Cells in Stroke Patients

The University of Texas Health Science Center, Houston

NCT00859014

COMPLETED NA 21 participants

REcurrent Stroke Prevention Through Personalized Education by Clinical Trainers (RESPPECT Trial)

Washington Regional Medical Center

NCT03861494

COMPLETED Phase 2 20 participants

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial

ProMedica Health System

NCT05172934

COMPLETED Phase 2 18 participants

Dietary Nitrate Supplements and Ischemic Stroke Recovery

Wake Forest University Health Sciences

NCT02838901

COMPLETED Phase 2 18 participants

Combination Anti-Platelet and Anti-Coagulation Treatment After Lysis of Ischemic Stroke Trial (CATALIST)

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00061373

COMPLETED Phase 1 16 participants

A Study to Evaluate the Effect of Diltiazem on the Pharmacokinetics (PK) of BMS-986141 in Healthy Subjects

Bristol-Myers Squibb

NCT02922452

COMPLETED NA 8 participants

Assessing the Safety and Effectiveness of a Neurological Thrombectomy Medical Device for Acute Ischemic Stroke

Jacobs institute

NCT05074186

COMPLETED NA 7 participants

IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion

University of North Carolina, Chapel Hill

NCT00624000

COMPLETED Early Phase 1 5 participants

Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke

Abington Memorial Hospital

NCT03352232

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 9
Phase 4 3

Named interventions

Most-linked intervention names on Ischemic Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Aspirin Drug
2 trials
Dilitazem Drug
1 trials
DESERVE education Behavioral
1 trials
dalfampridine-ER/placebo Drug
1 trials
placebo/dalfampridine-ER Drug
1 trials
intra-arterial tenecteplase Drug
1 trials
HBOT and OMT Combination
1 trials
eptifibatide Drug
1 trials

US sites by state

Facility locations filed on Ischemic Stroke trials. A trial with sites in several states counts in each.

California 19 trials
New York 16 trials
Florida 15 trials
Ohio 12 trials
Illinois 12 trials
Pennsylvania 11 trials
Massachusetts 11 trials
Georgia 11 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ischemic Stroke page

67 registered trials, 30 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ischemic Stroke condition card totals 67 registered trials; most-linked intervention Aspirin; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.