Penumbra
Trial Pipeline
A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)
NCT06747117
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
NCT04798261
BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis
NCT05003843
THUNDER: Acute Ischemic Stroke Study with the Penumbra System® Including Thunderbolt™ Aspiration Tubing
NCT05437055
Investigation of Clot in Ischemic Stroke and Hematoma Evacuation
NCT04693767
Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil
NCT02729740
Case Review of the Penumbra and Indigo Systems for Mechanical Thrombectomy in the Periphery
NCT02085551
Assess the Penumbra System in the Treatment of Acute Stroke
NCT01429350
Imaging Guided Patient Selection for Interventional Revascularization Therapy
NCT00963989
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
What the Pipeline for Penumbra Shows
According to the ClinicalTrials.gov registry, Penumbra is linked to 9 US clinical trials across every stage of research activity. Of those, 2 studies are currently recruiting — about 22% of the sponsor's indexed portfolio — and 6 are already marked complete, representing roughly 67% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Penumbra reports 1 late-stage studies (Phase 3 and Phase 4 combined) and 0 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Penumbra is Ischemic Stroke with 2 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.