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NCT04195061 · ClinicalTrials.gov registry record
Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity
A clinical trial of Insulin Resistance and Overweight and Obesity, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 28
- Enrollment target
- 1
- Study location
NCT04195061: Completed study of Insulin Resistance and Overweight and Obesity, sponsored by Massachusetts General Hospital.
NCT04195061 is a study of Insulin Resistance and Overweight and Obesity that has completed, run by Massachusetts General Hospital. The registered enrollment target is 28 participants, below the 245-participant average among 120 other Insulin Resistance trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04195061, a study of Insulin Resistance and Overweight and Obesity, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 28 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this research study is to learn more about the hormones that muscles make during exercise, and if those hormones are associated with type 2 diabetes risk in adults who are overweight or obese. Participants will undergo exercise testing on an upright bicycle, with blood samples taken for muscle hormones before and after exercise. The hypothesis is that adults with overweight/obesity and insulin resistance will have an impaired muscle hormone profile in response to exercise compared to adults with overweight/obesity who are not insulin resistant.
Primary Outcome
Percent change in serum myostatin levels from pre- to 3 hours post-cardiopulmonary exercise test
Conditions Studied
Interventions
- PROCEDURE Cardiopulmonary exercise test (CPET)
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2019-12-12 |
| Est. Completion | 2021-11-17 |
What the finished NCT04195061 record still lists
NCT04195061 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 245-participant average among 120 other Insulin Resistance trials with a reported enrollment target (89% lower).
The record links to 2 conditions, with Insulin Resistance appearing as the primary indexed condition, and to 1 intervention - of which Cardiopulmonary exercise test (CPET) is the first listed.
NCT04195061 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04195061 about?
NCT04195061 is a clinical study titled "Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity". The goal of this research study is to learn more about the hormones that muscles make during exercise, and if those hormones are associated with type 2 diabetes risk in adults who are overweight or obese. Participants will undergo exercise testing on an upright bicycle, with blood samples taken for ...
What is the current status of trial NCT04195061?
This trial is currently completed. The enrollment target is 28 participants. The study started on 2019-12-12. Estimated completion is 2021-11-17.
What conditions does trial NCT04195061 study?
This clinical trial studies the following conditions: Insulin Resistance, Overweight and Obesity.
What interventions are being tested in trial NCT04195061?
The interventions under investigation include: Cardiopulmonary exercise test (CPET) (PROCEDURE).
Who is sponsoring clinical trial NCT04195061?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04195061 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04195061's enrollment target sits among peer trials
28 93rd of 120 higher than 26 of 120 other Insulin Resistance trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Insulin Resistance trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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