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NCT02597101 · ClinicalTrials.gov registry record · Phase 2
Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes
A Phase 2 study of Type 2 Diabetes Mellitus and Insulin Resistance, sponsored by Nick Giannoukakis, PhD.
- Completed
- Registry status
- Phase 2
- Development phase
- 14
- Enrollment target
- 1
- Study location
NCT02597101 is a Phase 2 study of Type 2 Diabetes Mellitus and Insulin Resistance that has completed, run by Nick Giannoukakis, PhD. The registered enrollment target is 14 participants, below the 2,748-participant average among 122 other Type 2 Diabetes Mellitus trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02597101, a Phase 2 study of Type 2 Diabetes Mellitus and Insulin Resistance, has completed, sponsored by Nick Giannoukakis, PhD.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
The role of individual leukocyte populations in type 2 diabetes (T2D) and immunometabolism in general represent important gaps in knowledge to better understand the etiopathogenesis of T2D. Emerging evidence indicates that certain leukocyte populations serve as an important nexus of T2D-associated inflammation. This novel and innovative clinical trial will test the efficacy of a leukocyte-selective anti-inflammatory small drug as adjunctive therapy in improving insulin sensitivity in obese, insulin-resistant type 2 diabetic subjects. This trial also offers a first-in-kind opportunity to better understand the role of specific leukocyte populations in type 2 diabetes. The drug's clinical profile suggests that it will be well-tolerated with few, if any, side effects, and the existence of simple methods that can indirectly measure its activity in vivo
Conditions Studied
Interventions
- DRUG placebo
- DRUG Metformin
- DRUG saxagliptin
- DRUG AZD9668
Study Locations (1)
Pennsylvania
- Allegheny Health Network - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2015-11 |
| Est. Completion | 2019-06-15 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02597101
The ClinicalTrials.gov registry entry for NCT02597101 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,748-participant average among 122 other Type 2 Diabetes Mellitus trials with a reported enrollment target (99% lower). The listed sponsor is Nick Giannoukakis, PhD, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Type 2 Diabetes Mellitus appearing as the primary indexed condition, and to 4 interventions - of which placebo is the first listed.
NCT02597101 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT02597101 about?
NCT02597101 is a clinical study titled "Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes". The role of individual leukocyte populations in type 2 diabetes (T2D) and immunometabolism in general represent important gaps in knowledge to better understand the etiopathogenesis of T2D. Emerging evidence indicates that certain leukocyte populations serve as an important nexus of T2D-associated i...
What is the current status of trial NCT02597101?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2015-11. Estimated completion is 2019-06-15.
What conditions does trial NCT02597101 study?
This clinical trial studies the following conditions: Type 2 Diabetes Mellitus, Insulin Resistance.
What interventions are being tested in trial NCT02597101?
The interventions under investigation include: placebo (DRUG), Metformin (DRUG), saxagliptin (DRUG), AZD9668 (DRUG).
Who is sponsoring clinical trial NCT02597101?
This trial is sponsored by Nick Giannoukakis, PhD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02597101 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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