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NCT02327884 · ClinicalTrials.gov registry record
Characterization of Diseases With Salivary Gland Involvement
A clinical trial of Healthy Volunteer and Sjogren's Syndrome, sponsored by National Institute of Dental and Craniofacial Research (NIDCR).
- Recruiting
- Registry status
- 1,150
- Enrollment target
- 1
- Study location
NCT02327884: Recruiting study of Healthy Volunteer and Sjogren's Syndrome, sponsored by National Institute of Dental and Craniofacial Research (NIDCR).
NCT02327884 is a study of Healthy Volunteer and Sjogren's Syndrome that is actively recruiting participants, run by National Institute of Dental and Craniofacial Research (NIDCR). The registered enrollment target is 1,150 participants, above the 192-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (499% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02327884, a study of Healthy Volunteer and Sjogren's Syndrome, is actively recruiting participants, sponsored by National Institute of Dental and Craniofacial Research (NIDCR).
- RECRUITING
- Registry status
- 1,150 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- Salivary glands in and around the mouth and throat make saliva. Salivary gland disorders can affect a person s quality of life. Studying people who have a disease that affects their salivary gland(s) may teach researchers about the disorders and their genetics. Objectives: \- To study salivary gland diseases and disorders. To collect data and samples from people with salivary gland problems and their relatives. Eligibility: * People more than 4 years old who have or are suspected to have a disease involving salivary glands. * Their relatives more than 4 years old. * Healthy volunteers 18 years or older. Design: * Participants may be screened with: * Medical history * Physical exam * Blood and urine tests * General oral and dental history and exam * Saliva collection * Eye exam and test for dry eyes * Health questionnaires (adults) * Biopsy of some minor salivary glands. A small incision will be made on the inside of the lower lip and several tiny salivary glands will be removed. * Participants will have 2-3 visits. These may include: * Repeats of some screening tests * Ultrasounds of some glands. Researchers will put some gel on the face, then press on it with a smooth wand. * Adults may have other biopsies * A small catheter inserted into the opening of the parotid gland duct on the inside of the cheek. A saline solution (in a syringe) will fill the duct. * Swishing a saltwater solution in the mouth for 10 seconds and then spitting into a cup * Scrapings collected from teeth, tongue, and cheeks
Primary Outcome
hypothesis generating
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,150 participants |
| Start Date | 2015-04-03 |
| Est. Completion | 2032-04-01 |
What NCT02327884 shows while recruiting
NCT02327884 is an observational study that tracks outcomes without assigning an intervention. Its 1,150 participants enrollment target places it among the larger protocols in the corpus, above the 192-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (499% higher).
The record links to 3 conditions, with Healthy Volunteer appearing as the primary indexed condition, and to 0 interventions.
NCT02327884 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT02327884 about?
NCT02327884 is a clinical study titled "Characterization of Diseases With Salivary Gland Involvement". Background: \- Salivary glands in and around the mouth and throat make saliva. Salivary gland disorders can affect a person s quality of life. Studying people who have a disease that affects their salivary gland(s) may teach researchers about the disorders and their genetics. Objectives: \- To st...
What is the current status of trial NCT02327884?
This trial is currently recruiting. The enrollment target is 1,150 participants. The study started on 2015-04-03. Estimated completion is 2032-04-01.
What conditions does trial NCT02327884 study?
This clinical trial studies the following conditions: Healthy Volunteer, Sjogren's Syndrome, Salivary Gland Disease.
Who is sponsoring clinical trial NCT02327884?
This trial is sponsored by National Institute of Dental and Craniofacial Research (NIDCR), which has 91 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02327884 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02327884's enrollment target sits among peer trials
1,150 5th of 112 higher than 108 of 112 other Healthy Volunteer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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