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Healthy Volunteer: early-phase trial registry
49 of 113 indexed Healthy Volunteer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #113 of 28,707 conditions by registered trial count.
113 US clinical trials · 49 currently recruiting · #113 of 28,707 conditions by registered trial count
Healthy Volunteer: 113 US clinical trials tracked, 49 recruiting.
Healthy Volunteer is the subject of 113 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 86 in Phase 1-2 (earlier-stage). The most active sponsor is AbbVie, running 15 of these trials.
Enrollment posture brief
Registry condition healthy-volunteer
OPEN 49 | RECR 43% | LATE 0 | EARLY 86 | RANK #113 | SPON 15
Volume-matched condition peers
Nearest open-share peer: Bronchopulmonary Dysplasia (43% recruiting · 30 trials)
Healthy Volunteer lists 49 open slots (43% of 113 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Healthy Volunteer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Healthy Volunteer is recruiting above its size-band peers.
49 of 113 indexed trials (43.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Healthy Volunteer trials is spread across many organizations.
AbbVie accounts for 15 of 113 trials (13.3%). 56 distinct sponsors appear on at least one study for this condition label.
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Most Healthy Volunteer trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 113 trials that report a genuine target (sentinel values excluded). 80 of those (70.8%) plan for fewer than 100 participants.
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Healthy Volunteer research is mostly interventional.
95 interventional and 18 observational studies make up this index (84.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
113 total, page 2 of 3
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single Ascending Subcutaneous or Intravenous Doses of ABBV-701 in Healthy Adult Western and Asian Participants
AbbVie
NCT06895343
A Study to Assess the Adverse Events and How Subcutaneous (SC) Injections and Intravenous (IV) Infusions of ABBV-142 Move Through the Body of Healthy Adult Participants
AbbVie
NCT06774313
Evaluation of D3 Receptor Occupancy Using FLUORTRIOPRIDE ([18F]FTP) PET/CT
University of Pennsylvania
NCT02815917
A Multi-part Study of ALG-000184 to Evaluate Safety, Tolerability, Pharmacokinetics and Drug-drug Interaction Potential After Single and Multiple Doses in Healthy Volunteers
Aligos Therapeutics
NCT06672900
A Study to Evaluate Adverse Events, How the Drug is Tolerated, and How the Drug Moves Through the Body of Intravenous Infusions of ABBV-8736 in Adult Healthy Volunteers
AbbVie
NCT07141199
A Study to Assess Adverse Events and How Oral ABBV-932 Moves Through the Body When Given With Oral Itraconazole in Healthy Adult Participants
AbbVie
NCT07071532
Comparison of Pharmacokinetic Responses to Three Ketone Esters
NeuroEnergy Ventures
NCT07289165
Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT
University of Pennsylvania
NCT04062526
A Study to Assess the Relative Bioavailability of Oral ABBV-932 in Healthy Adult Participants
AbbVie
NCT06849791
A Phase 1 Study of Mosliciguat in Healthy, Adult Males
Pulmovant
NCT07185321
Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers
National Institute of Mental Health (NIMH)
NCT04339790
A Screening Study To Assess The Cognition Status in Healthy Volunteers
Hoffmann-La Roche
NCT01926873
Spaced Versus Massed Skill Learning
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00426465
A Study to Evaluate the Bioequivalence of Tocilizumab Following Subcutaneous Administration Via an Autoinjector (AI 1000-G2) Versus a Pre-Filled Syringe in Healthy Volunteers
Hoffmann-La Roche
NCT02678988
A Study of The Abuse Liability Potential of RO4917838 in Recreational Drug Users
Hoffmann-La Roche
NCT01438749
Study Assessing the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interactions of PTI-801 in Healthy Volunteers, and Safety, Tolerability, and Pharmacokinetics of PTI-801 in Subjects With Cystic Fibrosis
Proteostasis Therapeutics
NCT03140527
Bioequivalence Study of Denosumab CP4 Drug Product and Commercially Available Denosumab CP2 Drug Product
Amgen
NCT02053753
Drug-Drug Interaction Study With AZD9291 and Omeprazole in Healthy Volunteers
AstraZeneca
NCT02224053
Estimating Brain Biomechanics Using MRI
National Institutes of Health Clinical Center (CC)
NCT01633268
Systems Analyses of the Immune Response to the Seasonal Influenza Vaccine
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04025580
A Study to Determine the Safety, Tolerability, and Pharmacokinetics of GDC-0310 in Healthy Volunteers
Genentech
NCT02742779
Study to Assess the Safety, Tolerability, PK, ECG Effects, Food Effect, and Drug-drug Interaction (DDI) of Hormonal Contraceptives of PTI-428 in Healthy Female Volunteers
Proteostasis Therapeutics
NCT02846142
A Drug-Drug Interaction Study of the Effect of Rabeprazole, Itraconazole or Fluconazole on the Pharmacokinetics of Vismodegib
Genentech
NCT01772290
A Study of Danoprevir in Healthy Volunteers And Patients With Hepatic Impairment
Hoffmann-La Roche
NCT01185873
Phase I Study to Evaluate Bioavailability of Overencapsulated Celecoxib
POZEN
NCT00729495
A Study to Evaluate the Effect of Particle Size, Formulation and Food on the Pharmacokinetics of GDC-0032 in Healthy Volunteers
Genentech
NCT01980953
A Study to Evaluate the Bioavailability and Food Effects of Oral Venetoclax New Tablet Formulation 2.0 in Healthy Adult Female Participants
AbbVie
NCT06742086
Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men
Genzyme, a Sanofi Company
NCT01674036
Efficacy of B7A BSIgG Against E. Coli Strain B7A Challenge
Johns Hopkins Bloomberg School of Public Health
NCT03040687
Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single Ascending Doses of CC-92480 in Healthy Subjects
Celgene
NCT03803644
A Study to Assess the Impact of Speed and Site of Subcutaneous Injection on Pain, Tolerability, Safety, and Pharmacokinetics of Gantenerumab in Healthy Participants
Hoffmann-La Roche
NCT02882009
A Study to Investigate the Effects of Brensocatib on QT Interval in Healthy Participants
Insmed Incorporated
NCT05355935
Effect of Food on the Pharmacokinetics of Apremilast (CC-10004) in Healthy Adults
Amgen
NCT01634178
A Study of Aleglitazar in Combination With Aspirin in Healthy Volunteers
Hoffmann-La Roche
NCT01188304
A Pharmacodynamic and Pharmacokinetic Study of RO5508887 in Healthy Volunteers
Hoffmann-La Roche
NCT01592331
Effects of Transcranial Magnetic Stimulation (TMS) on Somatosensory Perception
National Center for Complementary and Integrative Health (NCCIH)
NCT02119637
A Study to Assess Electrophysiology, Safety, Tolerability, and Pharmacokinetics of Multiple Doses of SAGE-718 Using Ketamine Challenge in Healthy Subjects
Supernus Pharmaceuticals
NCT03844906
Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function
Atea Pharmaceuticals
NCT05724693
Safety, Tolerability and PK/PD of RB006 in a Healthy Volunteer SAD
Regado Biosciences
NCT01872572
A Drug Interaction Study of GDC-0032 Co-administered With Rifampin or Itraconazole in Healthy Volunteers
Genentech
NCT01814709
A Study to Evaluate Safety and Pharmacokinetics of BIIB104 in Healthy Japanese and Non-Japanese Participants
Biogen
NCT05148481
A Study to Investigate Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Healthy Volunteers
Genentech
NCT02596399
A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Volunteers.
Fore Biotherapeutics
NCT06385119
A Drug-Drug Interaction Study Between PF-06882961 and PF-06865571 in Healthy Adult Participants and Overweight Adults or Adults With Obesity Who Are Otherwise Healthy
Pfizer
NCT04839393
Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers
Vanda Pharmaceuticals
NCT04849559
A Study to Examine the Effects of Entinostat on Midazolam in Healthy Adult Subjects
Syndax Pharmaceuticals
NCT03187015
GSK1349572 Drug Interaction Study With Atazanavir/Ritonavir and Atazanavir
GlaxoSmithKline
NCT00883935
A Pharmacokinetic Study on Co-administration of Tamiflu (Oseltamivir) and Rimantadine in Healthy Volunteers
Hoffmann-La Roche
NCT01172847
A Phase I Dose Escalation Study of Plerixafor in Healthy Subjects of Japanese Descent
Genzyme, a Sanofi Company
NCT01579149
Safety, Tolerability, and Pharmacokinetics of IRL201104 in Healthy Volunteers
Revolo Biotherapeutics
NCT05921591
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 80 |
| Phase 2 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Healthy Volunteer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Healthy Volunteer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Healthy Volunteer page
113 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 49 Healthy Volunteer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- AbbVie sponsors the most Healthy Volunteer trials on record, review their full trial history before evaluating a specific study. See AbbVie's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Healthy Volunteer condition card totals 113 registered trials; most-linked intervention Placebo; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.