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NCT06989320 · ClinicalTrials.gov registry record · NA
Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease
A NA study of Healthy and Healthy Volunteer, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT06989320: Recruiting NA study of Healthy and Healthy Volunteer, sponsored by University of Alabama at Birmingham.
NCT06989320 is a NA study of Healthy and Healthy Volunteer that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 80 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06989320, a NA study of Healthy and Healthy Volunteer, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased production of oxalate by the body, which would lead to increased urinary excretion of oxalate. The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones. Participants will ingest fixed diets containing low amounts of oxalate for 5 days ingest a soluble form of glycolate and vitamin C collect urine, blood, stool during the dietary and oral dosing portions of the study and also collect breath sample during the oral glycolate test
Primary Outcome
Basal rate of endogenous oxalate synthesis estimated by repeat fasted hourly urine collections (mg/day)
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Low-oxalate diet and glycolate dosing
- DIETARY_SUPPLEMENT Oral glycolate dosing
- DIETARY_SUPPLEMENT Oral 13C- ascorbic acid dosing
Study Locations (2)
Alabama
- United States, Alabama University of Alabama at Birmingham - Birmingham
Texas
- University of Texas South Western Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-05-27 |
| Est. Completion | 2031-12-31 |
| Phase | NA |
What NCT06989320 shows while recruiting
NCT06989320 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower).
The record links to 9 conditions, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which Low-oxalate diet and glycolate dosing is the first listed.
NCT06989320 reports a single indexed study location in Alabama, Texas.
Frequently Asked Questions
What is clinical trial NCT06989320 about?
NCT06989320 is a clinical study titled "Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease". The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased production of oxalate by the body, which would lead to increased urinary excretion of oxalate. The study will recruit adult patients with a history of calcium oxalate kidney ...
What is the current status of trial NCT06989320?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2025-05-27. Estimated completion is 2031-12-31.
What conditions does trial NCT06989320 study?
This clinical trial studies the following conditions: Healthy, Healthy Volunteer, Nephrolithiasis, Kidney Stones, Urolithiasis.
What interventions are being tested in trial NCT06989320?
The interventions under investigation include: Low-oxalate diet and glycolate dosing (DIETARY_SUPPLEMENT), Oral glycolate dosing (DIETARY_SUPPLEMENT), Oral 13C- ascorbic acid dosing (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06989320?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06989320 being conducted?
This trial has 2 study locations across Alabama, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06989320's enrollment target sits among peer trials
80 274th of 1090 higher than 802 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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