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NCT03721822 · ClinicalTrials.gov registry record · Phase 1
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
A Phase 1 study of Healthy Volunteer and Smoking, Cigarette, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT03721822: Recruiting Phase 1 study of Healthy Volunteer and Smoking, Cigarette, sponsored by University of Pennsylvania.
NCT03721822 is a Phase 1 study of Healthy Volunteer and Smoking, Cigarette that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 100 participants, below the 201-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (50% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03721822, a Phase 1 study of Healthy Volunteer and Smoking, Cigarette, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called \[18F\]NOS. A radioactive tracer is a type of imaging drug that is labeled with a radioactive tag and injected into the body.
Primary Outcome
lung inflammation using \[18F\]NOS PET/CT and compare uptake in ENDS users to traditional cigarette smokers and non-smokers.
Conditions Studied
Interventions
- DRUG [18F]NOS
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2018-10-23 |
| Est. Completion | 2026-10-23 |
| Phase | Phase 1 |
What NCT03721822 shows while recruiting
NCT03721822 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 201-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (50% lower).
The record links to 3 conditions, with Healthy Volunteer appearing as the primary indexed condition, and to 1 intervention - of which [18F]NOS is the first listed.
NCT03721822 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03721822 about?
NCT03721822 is a clinical study titled "Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation". The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called \[18F\]NOS. A radioactive tracer is a type of imaging drug that is labeled with a radioactive tag and injected into the body.
What is the current status of trial NCT03721822?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2018-10-23. Estimated completion is 2026-10-23.
What conditions does trial NCT03721822 study?
This clinical trial studies the following conditions: Healthy Volunteer, Smoking, Cigarette, Smoking E-cigarette.
What interventions are being tested in trial NCT03721822?
The interventions under investigation include: [18F]NOS (DRUG).
Who is sponsoring clinical trial NCT03721822?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03721822 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Volunteer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03721822's enrollment target sits among peer trials
100 31st of 112 higher than 80 of 112 other Healthy Volunteer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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