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2026 data Public-data reference. official source

Bronchopulmonary Dysplasia

Open-data reference.

30 US clinical trials · 13 currently recruiting

Active & Recent Trials

RECRUITING NA 700 participants

Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)

University of Texas Southwestern Medical Center

NCT05849077

RECRUITING NA 478 participants

The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial

University of Pennsylvania

NCT05446272

RECRUITING Phase 2 338 participants

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

OHB Neonatology

NCT03253263

RECRUITING NA 222 participants

Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit

Shirley Ryan AbilityLab

NCT05568264

RECRUITING NA 218 participants

Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit

University of Florida

NCT06000761

RECRUITING 160 participants

MRI in BPD Subjects

Children's Hospital Medical Center, Cincinnati

NCT03657693

RECRUITING 130 participants

Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

Children's Hospital of Philadelphia

NCT06475976

RECRUITING 90 participants

Genesis Electrical Impedance Tomography (EIT): A Preliminary Study

University of Colorado, Denver

NCT03797183

RECRUITING 80 participants

Forced Oscillometry in Infants With Bronchopulmonary Dysplasia

Winston Manimtim

NCT04270045

RECRUITING NA 60 participants

Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia

Children's Hospital of Philadelphia

NCT06534359

RECRUITING Phase 1 30 participants

Inhaled Ciclesonide Study in Preterm Infants

Venkatesh Sampath

NCT06589245

RECRUITING NA 25 participants

Gastric Feeding Versus Transpyloric Feeding in Infants with Severe Bronchopulmonary Dysplasia, a Crossover Study

Le Bonheur Children's Hospital

NCT06821776

RECRUITING NA 24 participants

Ventilator Pressure and Optimization of Compliance and Hemodynamics

University of Alabama at Birmingham

NCT06512935

ACTIVE NOT RECRUITING NA 600 participants

Pulmonary Function Using Non-invasive Forced Oscillometry

University of Alabama at Birmingham

NCT03346343

ACTIVE NOT RECRUITING 526 participants

Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes

Nationwide Children's Hospital

NCT03782610

ACTIVE NOT RECRUITING 300 participants

A Cohort Study of the Intestinal Microbiota of Premature Infants

University of California, Davis

NCT03717584

COMPLETED Phase 3 800 participants

Hydrocortisone for BPD

NICHD Neonatal Research Network

NCT01353313

COMPLETED Phase 3 511 participants

Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia

Roberta Ballard

NCT01022580

COMPLETED Phase 3 451 participants

Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants

Mallinckrodt

NCT00931632

COMPLETED 277 participants

Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies

University of Rochester

NCT01607216

COMPLETED Phase 2 220 participants

Trial II of Lung Protection With Azithromycin in the Preterm Infant

Hubert Ballard

NCT00319956

COMPLETED Phase 2 109 participants

Safety of Sildenafil in Premature Infants

University of North Carolina, Chapel Hill

NCT03142568

COMPLETED Phase 1 104 participants

Delivery Room CPAP in Extremely Low Birth Weight Infants

NICHD Neonatal Research Network

NCT01223274

COMPLETED Phase 2 100 participants

Vitamin D Supplementation for Extremely Preterm Infants

University of Alabama at Birmingham

NCT01600430

COMPLETED Phase 2 88 participants

Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respiratory Distress Syndrome

Tufts Medical Center

NCT01941745

COMPLETED Phase 3 85 participants

Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide

Roberta Ballard

NCT00569530

COMPLETED Phase 2 82 participants

Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia (BPD)

University of North Carolina, Chapel Hill

NCT02527798

COMPLETED NA 20 participants

Relationship Between EIT and Respiratory Status in Very Preterm Infants

Lawrence Rhein

NCT06609135

COMPLETED NA 15 participants

Work of Breathing During Non-invasive Ventilation in Premature Neonates

Arkansas Children's Hospital Research Institute

NCT02788110

COMPLETED Phase 1 9 participants

Montelukast in Very Low Birthweight Infants

Children's Hospital Medical Center, Cincinnati

NCT00492102

Phase Distribution

PhaseTrial count
Early Phase 1 3
Phase 2 6
Phase 3 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Bronchopulmonary Dysplasia Trial Landscape

ClinicalTrials.gov lists 30 US studies indexed under Bronchopulmonary Dysplasia, and 13 of those are currently open to recruitment — roughly 43% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Bronchopulmonary Dysplasia shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Bronchopulmonary Dysplasia is led by University of Alabama at Birmingham with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 30 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Bronchopulmonary Dysplasia?

PlainTrial tracks 30 US clinical trials for Bronchopulmonary Dysplasia, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Bronchopulmonary Dysplasia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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