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NCT07261371 · ClinicalTrials.gov registry record · Phase 1

A Study to Compare Blood Levels of Different Dosage Formulations of the Study Medicine That Is a CGRP Receptor Antagonist in Healthy Adults

A Phase 1 study of Healthy Volunteer, sponsored by Pfizer.

Recruiting
Registry status
Phase 1
Development phase
64
Enrollment target
1
Study location

NCT07261371: Recruiting Phase 1 study of Healthy Volunteer, sponsored by Pfizer.

NCT07261371 is a Phase 1 study of Healthy Volunteer that is actively recruiting participants, run by Pfizer. The registered enrollment target is 64 participants, below the 201-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (68% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07261371, a Phase 1 study of Healthy Volunteer, is actively recruiting participants, sponsored by Pfizer.

RECRUITING
Registry status
Phase 1
Development phase
64 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to assess the bioequivalence (medicines that may have different names or be made in different ways, but have the same effect on the body) of different formulations of a CGRP receptor antagonist in healthy adult participants. The study is seeking participants who are: 1. Healthy males and females 18 years of age or older 2. Willing and able to comply with all scheduled visits, treatment plan, lifestyle considerations, and other study procedures. 3. Body Mass Index of 16-32 kilogram per meter squared (kg/m2); and a total body weight \>45 kg The study will help the team understand how difference in formulation may, or may not, affect how the medicine is absorbed, processed, and removed by the body.

Conditions Studied

Interventions

  • DRUG Test formulation (Treatment A)
  • DRUG Reference formulation (Treatment B)
  • DRUG Test formulation (Treatment C)
  • DRUG Test formulation (Treatment D)

Study Locations (1)

Connecticut

  • Pfizer Clinical Research Unit - New Haven - New Haven

Trial Details

FieldValue
Enrollment Target 64 participants
Start Date 2025-11-24
Est. Completion 2026-05-13
Phase Phase 1
Pfizer

1,845 total trials

What NCT07261371 shows while recruiting

NCT07261371 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, below the 201-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (68% lower).

The record links to 1 condition, with Healthy Volunteer appearing as the primary indexed condition, and to 4 interventions - of which Test formulation (Treatment A) is the first listed.

NCT07261371 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT07261371 about?

NCT07261371 is a clinical study titled "A Study to Compare Blood Levels of Different Dosage Formulations of the Study Medicine That Is a CGRP Receptor Antagonist in Healthy Adults". The purpose of this study is to assess the bioequivalence (medicines that may have different names or be made in different ways, but have the same effect on the body) of different formulations of a CGRP receptor antagonist in healthy adult participants. The study is seeking participants who are: 1...

What is the current status of trial NCT07261371?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 64 participants. The study started on 2025-11-24. Estimated completion is 2026-05-13.

What conditions does trial NCT07261371 study?

This clinical trial studies the following conditions: Healthy Volunteer.

What interventions are being tested in trial NCT07261371?

The interventions under investigation include: Test formulation (Treatment A) (DRUG), Reference formulation (Treatment B) (DRUG), Test formulation (Treatment C) (DRUG), Test formulation (Treatment D) (DRUG).

Who is sponsoring clinical trial NCT07261371?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07261371 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07261371's enrollment target sits among peer trials

64 53rd of 112 higher than 60 of 112 other Healthy Volunteer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Volunteer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07261371, the US trial registry maintained by the National Library of Medicine. NCT07261371 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.