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NCT03746769 · ClinicalTrials.gov registry record · Phase 1

Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes

A Phase 1 study of Diabetes Mellitus, Type 1, sponsored by City of Hope Medical Center.

Recruiting
Registry status
Phase 1
Development phase
20
Enrollment target
1
Study location

NCT03746769 is a Phase 1 study of Diabetes Mellitus, Type 1 that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 20 participants, below the 1,266-participant average among 118 other Diabetes Mellitus, Type 1 trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03746769, a Phase 1 study of Diabetes Mellitus, Type 1, is actively recruiting participants, sponsored by City of Hope Medical Center.

RECRUITING
Registry status
Phase 1
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

This clinical study will evaluate the safety and effectiveness of Gastrin treatment with islet transplantation to help patients with difficult to control type 1 diabetes make insulin again and improve blood sugar control. This study involves two investigational (experimental) products not yet approved by the U.S. Food and Drug Administration (FDA) as a treatment for any disease: 1. Human allogenic islet cells (islet cells from a deceased, unrelated human donor) 2. Gastrin-17 (Gastrin) - a hormone secreted by the gut

Conditions Studied

Diabetes Mellitus, Type 1

Interventions

  • BIOLOGICAL Allogenic Human Islet Cells
  • DRUG Gastrin 17

Study Locations (1)

California

  • City of Hope Medical Center - Duarte

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2019-07-07
Est. Completion 2028-08-01
Phase Phase 1

Sponsor

City of Hope Medical Center

582 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03746769

The ClinicalTrials.gov registry entry for NCT03746769 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,266-participant average among 118 other Diabetes Mellitus, Type 1 trials with a reported enrollment target (98% lower). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Diabetes Mellitus, Type 1 appearing as the primary indexed condition, and to 2 interventions - of which Allogenic Human Islet Cells is the first listed.

NCT03746769 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03746769 about?

NCT03746769 is a clinical study titled "Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes". This clinical study will evaluate the safety and effectiveness of Gastrin treatment with islet transplantation to help patients with difficult to control type 1 diabetes make insulin again and improve blood sugar control. This study involves two investigational (experimental) products not yet appro...

What is the current status of trial NCT03746769?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2019-07-07. Estimated completion is 2028-08-01.

What conditions does trial NCT03746769 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 1.

What interventions are being tested in trial NCT03746769?

The interventions under investigation include: Allogenic Human Islet Cells (BIOLOGICAL), Gastrin 17 (DRUG).

Who is sponsoring clinical trial NCT03746769?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03746769 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.