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NCT06325202 · ClinicalTrials.gov registry record · NA
Closed Loop and Education for Hypoglycemia Awareness Restoration
A NA study of Diabetes Mellitus, Type 1, sponsored by Milton S. Hershey Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 324
- Enrollment target
- 8
- Study locations
NCT06325202: Recruiting NA study of Diabetes Mellitus, Type 1, sponsored by Milton S. Hershey Medical Center.
NCT06325202 is a NA study of Diabetes Mellitus, Type 1 that is actively recruiting participants, run by Milton S. Hershey Medical Center. The registered enrollment target is 324 participants, below the 1,263-participant average among 118 other Diabetes Mellitus, Type 1 trials with a reported enrollment target (74% lower). The trial reports 8 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06325202, a NA study of Diabetes Mellitus, Type 1, is actively recruiting participants, sponsored by Milton S. Hershey Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 324 participants
- Enrollment target
- 8
- Study locations
Study Summary
The purpose of the CLEAR study is to determine the effect on counterregulatory responses (CRR) of intervening (by attempting to strictly avoid hypoglycemia) to improve awareness of hypoglycemic symptoms among adults with type 1 diabetes (T1D) who have impaired awareness of hypoglycemia (IAH). IAH affects 20-25% of adults with T1D, and rises with increasing duration of T1D.
Primary Outcome
a change in epinephrine (pg/ml) that exceeds 125 pg/ml between (1) 12 months and baseline, and (2) 24 months and baseline
Conditions Studied
Interventions
- DEVICE Omnipod 5 or Medtronic 780G
- BEHAVIORAL My HypoCOMPaSS Education
- BEHAVIORAL HARPdoc Education
Study Locations (8)
Other
- University of Leicester - Leicester
- University of Sheffield - Sheffield
California
- University of California, San Diego - La Jolla
Florida
- AdventHealth - Orlando
Kentucky
- University of Kentucky - Lexington
Minnesota
- University of Minnesota - Minneapolis
Pennsylvania
- University of Pennsylvania - Philadelphia
Victoria
- University of Melbourne - Fitzroy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 324 participants |
| Start Date | 2025-10-03 |
| Est. Completion | 2029-07-31 |
| Phase | NA |
What NCT06325202 shows while recruiting
NCT06325202 is an interventional study that assigns participants to a tested intervention. The registered 324 participants enrollment target is mid-sized for trials with a published cap, below the 1,263-participant average among 118 other Diabetes Mellitus, Type 1 trials with a reported enrollment target (74% lower).
The record links to 1 condition, with Diabetes Mellitus, Type 1 appearing as the primary indexed condition, and to 3 interventions - of which Omnipod 5 or Medtronic 780G is the first listed.
NCT06325202 lists 8 locations in 7 states (Other, California, Florida).
Frequently Asked Questions
What is clinical trial NCT06325202 about?
NCT06325202 is a clinical study titled "Closed Loop and Education for Hypoglycemia Awareness Restoration". The purpose of the CLEAR study is to determine the effect on counterregulatory responses (CRR) of intervening (by attempting to strictly avoid hypoglycemia) to improve awareness of hypoglycemic symptoms among adults with type 1 diabetes (T1D) who have impaired awareness of hypoglycemia (IAH). IAH af...
What is the current status of trial NCT06325202?
This trial is currently recruiting. It is a NA study. The enrollment target is 324 participants. The study started on 2025-10-03. Estimated completion is 2029-07-31.
What conditions does trial NCT06325202 study?
This clinical trial studies the following conditions: Diabetes Mellitus, Type 1.
What interventions are being tested in trial NCT06325202?
The interventions under investigation include: Omnipod 5 or Medtronic 780G (DEVICE), My HypoCOMPaSS Education (BEHAVIORAL), HARPdoc Education (BEHAVIORAL).
Who is sponsoring clinical trial NCT06325202?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06325202 being conducted?
This trial has 8 study locations across California, Florida, Kentucky, Minnesota, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetes Mellitus, Type 1
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06325202's enrollment target sits among peer trials
324 22nd of 118 higher than 97 of 118 other Diabetes Mellitus, Type 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetes Mellitus, Type 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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