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Closed Loop and Education for Hypoglycemia Awareness Restoration
NCT06325202 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of the CLEAR study is to determine the effect on counterregulatory responses (CRR) of intervening (by attempting to strictly avoid hypoglycemia) to improve awareness of hypoglycemic symptoms among adults with type 1 diabetes (T1D) who have impaired awareness of hypoglycemia (IAH). IAH affects 20-25% of adults with T1D, and rises with increasing duration of T1D.
Conditions Studied
Interventions
- DEVICE Omnipod 5 or Medtronic 780G
- BEHAVIORAL My HypoCOMPaSS Education
- BEHAVIORAL HARPdoc Education
Study Locations (8)
Other
- University of Leicester — Leicester
- University of Sheffield — Sheffield
California
- University of California, San Diego — La Jolla
Florida
- AdventHealth — Orlando
Kentucky
- University of Kentucky — Lexington
Minnesota
- University of Minnesota — Minneapolis
Pennsylvania
- University of Pennsylvania — Philadelphia
Victoria
- University of Melbourne — Fitzroy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 324 participants |
| Start Date | 2025-10-03 |
| Est. Completion | 2029-07-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06325202
The ClinicalTrials.gov registry entry for NCT06325202 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 324 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Milton S. Hershey Medical Center, which has 277 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Diabetes Mellitus, Type 1 appearing as the primary indexed condition, and to 3 interventions — of which Omnipod 5 or Medtronic 780G is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06325202 reports 8 study locations spanning 7 distinct geographic areas — top geographies include Other, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06325202 about?
NCT06325202 is a clinical study titled "Closed Loop and Education for Hypoglycemia Awareness Restoration". The purpose of the CLEAR study is to determine the effect on counterregulatory responses (CRR) of intervening (by attempting to strictly avoid hypoglycemia) to improve awareness of hypoglycemic symptoms among adults with type 1 diabetes (T1D) who have impaired awareness of hypoglycemia (IAH). IAH af...
What is the current status of trial NCT06325202?
This trial is currently recruiting. It is a NA study. The enrollment target is 324 participants. The study started on 2025-10-03. Estimated completion is 2029-07-31.
What conditions does trial NCT06325202 study?
This clinical trial studies the following conditions: Diabetes Mellitus, Type 1. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06325202?
The interventions under investigation include: Omnipod 5 or Medtronic 780G (DEVICE), My HypoCOMPaSS Education (BEHAVIORAL), HARPdoc Education (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06325202?
This trial is sponsored by Milton S. Hershey Medical Center, which has 277 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06325202 being conducted?
This trial has 8 study locations across California, Florida, Kentucky, Minnesota, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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