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NCT05317455 · ClinicalTrials.gov registry record · Early Phase 1
Regulation of Brain Glucose Metabolism in Type 1 Diabetes
A Early Phase 1 study of Diabetes Mellitus, Type 1 and Hypoglycemia Unawareness, sponsored by Yale University.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT05317455 is a Early Phase 1 study of Diabetes Mellitus, Type 1 and Hypoglycemia Unawareness that is actively recruiting participants, run by Yale University. The registered enrollment target is 16 participants, below the 1,266-participant average among 118 other Diabetes Mellitus, Type 1 trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05317455, a Early Phase 1 study of Diabetes Mellitus, Type 1 and Hypoglycemia Unawareness, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective randomized placebo-controlled double-blind crossover pilot study determining the effect of dichloroacetate on brain function under clamped hypoglycemia in T1DM.
Conditions Studied
Interventions
- DRUG Dichloroacetate
Study Locations (1)
Connecticut
- Yale-New Haven Hospital - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-05-13 |
| Est. Completion | 2026-06-30 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05317455
The ClinicalTrials.gov registry entry for NCT05317455 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,266-participant average among 118 other Diabetes Mellitus, Type 1 trials with a reported enrollment target (99% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Diabetes Mellitus, Type 1 appearing as the primary indexed condition, and to 1 intervention - of which Dichloroacetate is the first listed.
NCT05317455 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT05317455 about?
NCT05317455 is a clinical study titled "Regulation of Brain Glucose Metabolism in Type 1 Diabetes". This is a prospective randomized placebo-controlled double-blind crossover pilot study determining the effect of dichloroacetate on brain function under clamped hypoglycemia in T1DM.
What is the current status of trial NCT05317455?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 16 participants. The study started on 2025-05-13. Estimated completion is 2026-06-30.
What conditions does trial NCT05317455 study?
This clinical trial studies the following conditions: Diabetes Mellitus, Type 1, Hypoglycemia Unawareness.
What interventions are being tested in trial NCT05317455?
The interventions under investigation include: Dichloroacetate (DRUG).
Who is sponsoring clinical trial NCT05317455?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05317455 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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