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ClinicalTrials.gov 24 recruiting now official registry

Delirium clinical trials

24 of 63 indexed Delirium trials are currently recruiting.

63 US clinical trials · 24 currently recruiting

Delirium is the subject of 63 registered US clinical trials on ClinicalTrials.gov, 24 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 5 of these trials.

The research picture

Delirium has 63 registered US clinical trials, 24 of them open to new participants right now, about 38% of the total.

24
recruiting participants now
38%
of trials open to enrollment
9
in Phase 3–4 (later-stage)
5
top sponsor: Vanderbilt University Medical Center
Phase 12Phase 28Phase 36Phase 43

Active & Recent Trials

63 total, page 2 of 2

COMPLETED 124 participants

Ketamine Infusion as Sedative Analgesic in Severe ARDS

Interfaith Medical Center

NCT04818827

COMPLETED 102 participants

Delirium in Mechanically Ventilated Patients

University of Chicago

NCT00919698

COMPLETED Phase 2 100 participants

MENDS Study: Trial in Ventilated ICU Patients Comparing an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status

Vanderbilt University

NCT00095251

COMPLETED Phase 4 100 participants

Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients?

Maisonneuve-Rosemont Hospital

NCT01791296

COMPLETED Phase 2 66 participants

High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation

UNC Lineberger Comprehensive Cancer Center

NCT03263442

COMPLETED Phase 2 52 participants

The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

Mayo Clinic

NCT02554253

COMPLETED NA 49 participants

Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium

Virginia Commonwealth University

NCT06161480

COMPLETED NA 45 participants

Prevention of Early Postoperative Decline

Beth Israel Deaconess Medical Center

NCT02908464

COMPLETED 38 participants

Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium

Massachusetts General Hospital

NCT03498560

COMPLETED 34 participants

Remote Cognitive Assessment for Surgical Patients

University of California, San Francisco

NCT05566275

COMPLETED NA 30 participants

Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients

The Methodist Hospital Research Institute

NCT06232317

COMPLETED Phase 1 10 participants

Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine

Mayo Clinic

NCT02131545

COMPLETED 6 participants

Helping Older Persons Emerge Stronger

Ohio State University

NCT02863081

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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 8
Phase 3 6
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Delirium Trial Landscape

63 indexed Delirium studies · 24 recruiting (38%).

Phase mix: 9 late (III/IV) vs 10 early (I/II).

Top sponsor: Vanderbilt University Medical Center (5 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Delirium?

PlainTrial tracks 63 US clinical trials for Delirium, of which 24 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Delirium?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.