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ClinicalTrials.gov 24 recruiting now full pipeline

Delirium: full-pipeline trial registry

24 of 63 indexed Delirium trials are currently recruiting.

Corpus placement: #222 of 28,707 conditions by registered trial count.

63 US clinical trials · 24 currently recruiting · #222 of 28,707 conditions by registered trial count

Delirium: 63 US clinical trials tracked, 24 recruiting.

Delirium is the subject of 63 registered US clinical trials on ClinicalTrials.gov, 24 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 5 of these trials.

Enrollment posture brief

Registry condition delirium

OPEN 24 | RECR 38% | LATE 9 | EARLY 10 | RANK #222 | SPON 5

Nearest open-share peer: Behavior, Health (38% recruiting · 21 trials)

Hematopoietic and Lymphatic 76.2%Mental Health54%Pancreatic Adenocarcinoma49.2%Delirium (this)38%Hypercholesterolemia7.9%
Open-enrollment share among volume-matched conditions near Delirium

Delirium lists 24 open slots (38% of 63 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Delirium on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Delirium recruits in line with its size-band peers.

    24 of 63 indexed trials (38.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Delirium trials is spread across many organizations.

    Vanderbilt University Medical Center accounts for 5 of 63 trials (7.9%). 39 distinct sponsors appear on at least one study for this condition label.

  3. Typical Delirium enrolment sits around 135 participants.

    Median target enrolment is 135 among the 63 trials that report a genuine target (sentinel values excluded). 21 of those (33.3%) plan for fewer than 100 participants.

  4. Delirium splits between interventional and observational designs.

    44 interventional and 19 observational studies make up this index (69.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 28Phase 36Phase 43

Open and recent trials

63 total, page 2 of 2

COMPLETED 124 participants

Ketamine Infusion as Sedative Analgesic in Severe ARDS

Interfaith Medical Center

NCT04818827

COMPLETED 102 participants

Delirium in Mechanically Ventilated Patients

University of Chicago

NCT00919698

COMPLETED Phase 2 100 participants

MENDS Study: Trial in Ventilated ICU Patients Comparing an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status

Vanderbilt University

NCT00095251

COMPLETED Phase 4 100 participants

Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients?

Maisonneuve-Rosemont Hospital

NCT01791296

COMPLETED Phase 2 66 participants

High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation

UNC Lineberger Comprehensive Cancer Center

NCT03263442

COMPLETED Phase 2 52 participants

The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

Mayo Clinic

NCT02554253

COMPLETED NA 49 participants

Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium

Virginia Commonwealth University

NCT06161480

COMPLETED NA 45 participants

Prevention of Early Postoperative Decline

Beth Israel Deaconess Medical Center

NCT02908464

COMPLETED 38 participants

Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium

Massachusetts General Hospital

NCT03498560

COMPLETED 34 participants

Remote Cognitive Assessment for Surgical Patients

University of California, San Francisco

NCT05566275

COMPLETED NA 30 participants

Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients

The Methodist Hospital Research Institute

NCT06232317

COMPLETED Phase 1 10 participants

Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine

Mayo Clinic

NCT02131545

COMPLETED 6 participants

Helping Older Persons Emerge Stronger

Ohio State University

NCT02863081

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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 8
Phase 3 6
Phase 4 3

Named interventions

Most-linked intervention names on Delirium records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Dexmedetomidine Drug
5 trials
Haloperidol Drug
5 trials
Placebo Drug
5 trials
Placebo Other
3 trials
Light Level Monitoring Other
2 trials
Noise Level Monitoring Other
2 trials
Accelerometer Monitoring Other
2 trials
Video Monitoring Other
2 trials

US sites by state

Facility locations filed on Delirium trials. A trial with sites in several states counts in each.

Massachusetts 12 trials
New York 11 trials
California 11 trials
Tennessee 10 trials
Texas 9 trials
Pennsylvania 6 trials
Ohio 6 trials
North Carolina 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Delirium page

63 registered trials, 24 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Delirium condition card totals 63 registered trials; most-linked intervention Dexmedetomidine; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.