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NCT06969287 · ClinicalTrials.gov registry record · Phase 3
Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
A Phase 3 study of Delirium and Surgery--Complications, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT06969287: Recruiting Phase 3 study of Delirium and Surgery--Complications, sponsored by Washington University School of Medicine.
NCT06969287 is a Phase 3 study of Delirium and Surgery--Complications that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 46 participants, below the 887-participant average among 62 other Delirium trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06969287, a Phase 3 study of Delirium and Surgery--Complications, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigation will establish biological plausibility and infrastructure required for a multisite clinical trial evaluating the re-purposing of fluvoxamine to mitigate postoperative delirium risk in geriatric patients undergoing non-cardiac non-intracranial surgery.
Primary Outcome
Feasibility assessed as number of eligible participants enrolled per month by an audit of the study screening and recruitment logs.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Fluvoxamine
Study Locations (1)
Missouri
- Washington University School of Medicine/Barnes-Jewish Hospital - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2026-03-07 |
| Est. Completion | 2028-04-01 |
| Phase | Phase 3 |
What NCT06969287 shows while recruiting
NCT06969287 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 887-participant average among 62 other Delirium trials with a reported enrollment target (95% lower).
The record links to 2 conditions, with Delirium appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06969287 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT06969287 about?
NCT06969287 is a clinical study titled "Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery". The investigation will establish biological plausibility and infrastructure required for a multisite clinical trial evaluating the re-purposing of fluvoxamine to mitigate postoperative delirium risk in geriatric patients undergoing non-cardiac non-intracranial surgery.
What is the current status of trial NCT06969287?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 46 participants. The study started on 2026-03-07. Estimated completion is 2028-04-01.
What conditions does trial NCT06969287 study?
This clinical trial studies the following conditions: Delirium, Surgery--Complications.
What interventions are being tested in trial NCT06969287?
The interventions under investigation include: Placebo (DRUG), Fluvoxamine (DRUG).
Who is sponsoring clinical trial NCT06969287?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06969287 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Delirium
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06969287's enrollment target sits among peer trials
46 52nd of 62 higher than 11 of 62 other Delirium trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Delirium trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
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PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
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The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure
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The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study
COMPLETED · Phase 3
-
Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation
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