Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04093219 · ClinicalTrials.gov registry record · Phase 3
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
A Phase 3 study of Coronary Artery Disease and Delirium, sponsored by Beth Israel Deaconess Medical Center.
- Active
- Registry status
- Phase 3
- Development phase
- 900
- Enrollment target
- 10
- Study locations
NCT04093219 is a Phase 3 study of Coronary Artery Disease and Delirium that is active but no longer recruiting, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 900 participants, below the 1,283-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (30% lower). The trial reports 10 study locations across 6 states.
The verdict
NCT04093219, a Phase 3 study of Coronary Artery Disease and Delirium, is active but no longer recruiting, sponsored by Beth Israel Deaconess Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 900 participants
- Enrollment target
- 10
- Study locations
Study Summary
Our objective is to find an effective prophylactic intervention by evaluating IV acetaminophen's impact in reducing the frequency of postoperative delirium, one of the most common and detrimental complications of cardiac surgery in older adults.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG IV acetaminophen
Study Locations (10)
Massachusetts
- Massachusetts General Hospital - Boston
- Brigham and Women's Hospital - Boston
- Beth Israel Deaconess Medical Center - Boston
California
- University of California Irvine - Irvine
- University of California Los Angeles - Los Angeles
New York
- Columbia University Irving Medical Center - New York
- Albert Einstein College of Medicine- Montefiore - The Bronx
Alabama
- University of Alabama at Birmingham - Birmingham
Connecticut
- Yale University/Yale New Haven Hospital - New Haven
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 900 participants |
| Start Date | 2020-08-11 |
| Est. Completion | 2026-03-04 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04093219
The ClinicalTrials.gov registry entry for NCT04093219 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 900 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,283-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (30% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04093219 reports 10 study locations spanning 6 distinct geographic areas - top geographies include Massachusetts, California, New York.
Frequently Asked Questions
What is clinical trial NCT04093219 about?
NCT04093219 is a clinical study titled "PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients". Our objective is to find an effective prophylactic intervention by evaluating IV acetaminophen's impact in reducing the frequency of postoperative delirium, one of the most common and detrimental complications of cardiac surgery in older adults.
What is the current status of trial NCT04093219?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 900 participants. The study started on 2020-08-11. Estimated completion is 2026-03-04.
What conditions does trial NCT04093219 study?
This clinical trial studies the following conditions: Coronary Artery Disease, Delirium, Delirium in Old Age.
What interventions are being tested in trial NCT04093219?
The interventions under investigation include: Placebo (OTHER), IV acetaminophen (DRUG).
Who is sponsoring clinical trial NCT04093219?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04093219 being conducted?
This trial has 10 study locations across Alabama, California, Connecticut, Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Coronary Artery Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
RECRUITING · Phase 3
-
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
RECRUITING · Phase 3
-
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
RECRUITING · Phase 3
-
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities
RECRUITING · Phase 3
-
Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
ACTIVE NOT RECRUITING · Phase 3
-
Cardiovascular Outcomes Of Diet Counseling
COMPLETED · Phase 3
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.