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NCT05915377 · ClinicalTrials.gov registry record · NA
Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation
A NA study of Delirium and Delirium in Old Age, sponsored by Penn State University.
- Recruiting
- Registry status
- NA
- Development phase
- 1,050
- Enrollment target
- 2
- Study locations
NCT05915377: Recruiting NA study of Delirium and Delirium in Old Age, sponsored by Penn State University.
NCT05915377 is a NA study of Delirium and Delirium in Old Age that is actively recruiting participants, run by Penn State University. The registered enrollment target is 1,050 participants, above the 871-participant average among 62 other Delirium trials with a reported enrollment target (21% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05915377, a NA study of Delirium and Delirium in Old Age, is actively recruiting participants, sponsored by Penn State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,050 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this step-wedge trial is to test the implementation of daily nurse screening for delirium in routine care and its impact on outcomes and complications in hospitalized older adults admitted to 6 general medicine/surgery units at 3 hospitals in Pennsylvania and Massachusetts. The main question\[s\] it aims to answer are: * 1\. To test the fidelity, accuracy, and durability of implementing daily nurse screening for delirium using the UB-CAM in routine care. * 2\. To evaluate the impact of UB-CAM delirium screening on patient and care partner centered outcomes assessed at one month follow-up interviews 3. To evaluate the impact of UB-CAM screening on rates of delirium complications (falls, pressure injury, aspiration) and adverse delirium management (psychoactive medication use, restraint use). Participants (patients) will be assessed for delirium on study days 1, 2 and 3 (or until hospital discharge) and will be asked basic demographics. These patients will be contacted by phone 1 month after enrollment to collect information about inpatient facility use and to administer the Delirium Burden Patient Scale. Participants (care partners) will be interviewed at the patient's discharge to complete the Alzheimer's Disease-8 scale. These care partners will be contacted by phone 1 month after enrollment to complete the Delirium Burden Caregiver Scale and to complete a Qualitative Interview which includes questions about communication and collaboration.
Primary Outcome
Accuracy is defined as the percent agreement between the nurse UB-CAM screen and the RSDA. While false negatives (low sensitivity) are most concerning since delirium is missed, false positives are problematic as well, as they lead to false labeling and unnecessary workups, which burden both patients and hospital staff. In subset analyses, the investigators will also consider sensitivity (among all RSDA positives) and specificity (among all RSDA negatives). Our sample size of 2360 assessments and
Conditions Studied
Interventions
- OTHER READI-SET GO UB-CAM delirium screening into EHR
Study Locations (2)
Massachusetts
- Beth Israel Deaconness Medical Center - Boston
Pennsylvania
- Mount Nittany Medical Center - State College
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,050 participants |
| Start Date | 2024-04-03 |
| Est. Completion | 2028-05 |
| Phase | NA |
What NCT05915377 shows while recruiting
NCT05915377 is an interventional study that assigns participants to a tested intervention. Its 1,050 participants enrollment target places it among the larger protocols in the corpus, above the 871-participant average among 62 other Delirium trials with a reported enrollment target (21% higher).
The record links to 4 conditions, with Delirium appearing as the primary indexed condition, and to 1 intervention - of which READI-SET GO UB-CAM delirium screening into EHR is the first listed.
NCT05915377 reports a single indexed study location in Massachusetts, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05915377 about?
NCT05915377 is a clinical study titled "Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation". The goal of this step-wedge trial is to test the implementation of daily nurse screening for delirium in routine care and its impact on outcomes and complications in hospitalized older adults admitted to 6 general medicine/surgery units at 3 hospitals in Pennsylvania and Massachusetts. The main que...
What is the current status of trial NCT05915377?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,050 participants. The study started on 2024-04-03. Estimated completion is 2028-05.
What conditions does trial NCT05915377 study?
This clinical trial studies the following conditions: Delirium, Delirium in Old Age, Delirium Superimposed on Dementia, Delirium With Dementia.
What interventions are being tested in trial NCT05915377?
The interventions under investigation include: READI-SET GO UB-CAM delirium screening into EHR (OTHER).
Who is sponsoring clinical trial NCT05915377?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05915377 being conducted?
This trial has 2 study locations across Massachusetts, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05915377's enrollment target sits among peer trials
1,050 6th of 62 higher than 57 of 62 other Delirium trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Delirium trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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