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NCT03928236 · ClinicalTrials.gov registry record · NA

Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium

A NA study of Delirium and Post-cardiac Surgery, sponsored by Population Health Research Institute.

Active
Registry status
NA
Development phase
15,886
Enrollment target
20
Study locations

NCT03928236 is a NA study of Delirium and Post-cardiac Surgery that is active but no longer recruiting, run by Population Health Research Institute. The registered enrollment target is 15,886 participants, above the 631-participant average among 62 other Delirium trials with a reported enrollment target (2418% higher). The trial reports 20 study locations across 9 states.

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The verdict

NCT03928236, a NA study of Delirium and Post-cardiac Surgery, is active but no longer recruiting, sponsored by Population Health Research Institute.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
15,886 participants
Enrollment target
20
Study locations

Study Summary

B-FREE is a pragmatic, multicentre, cluster crossover trial evaluating whether a policy limiting the use of intra-operative benzodiazepine reduces post-operative delirium when compared with a policy of 'ad libitum' administration. The knowledge generated by this study will provide the basis for cardiac anesthesia practice guidelines.

Interventions

  • OTHER Limited Intraoperative Benzodiazepine
  • OTHER Liberal Intraoperative Benzodiazepine

Study Locations (20)

Ontario

  • Hamilton Health Sciences, Hamilton General Hospital - Hamilton
  • Kingston General Hospital - Kingston
  • London Health Sciences Centre - London
  • Sunnybrook Health Sciences Centre - Toronto
  • St. Michael's Hospital - Toronto
  • Toronto General Hospital - Toronto

Quebec

  • Montreal Heart Institute - Montreal
  • Jewish General Hospital - Montreal
  • Hôpital Laval - Québec
  • Centre Hospitalier Universitaire de Sherbrooke - Sherbrooke

British Columbia

  • Royal Columbian Hospital - New Westminster
  • Vancouver General Hospital - Vancouver
  • St. Paul's Hospital - Vancouver

Saskatchewan

  • Regina General Hospital - Regina
  • Royal University Hospital - Saskatoon

Missouri

  • Washington University School of Medicine - St Louis

New York

  • Weill Cornell Medicine - New York

Alberta

  • Mazankowski Alberta Heart Institute - Edmonton

Manitoba

  • St. Boniface General Hospital - Winnipeg

Trial Details

FieldValue
Enrollment Target 15,886 participants
Start Date 2019-11-18
Est. Completion 2025-04-30
Phase NA

What the Registry Record Tells You About NCT03928236

The ClinicalTrials.gov registry entry for NCT03928236 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 15,886 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 631-participant average among 62 other Delirium trials with a reported enrollment target (2418% higher). The listed sponsor is Population Health Research Institute, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Delirium appearing as the primary indexed condition, and to 2 interventions - of which Limited Intraoperative Benzodiazepine is the first listed.

NCT03928236 reports 20 study locations spanning 9 distinct geographic areas - top geographies include Ontario, Quebec, British Columbia.

Frequently Asked Questions

What is clinical trial NCT03928236 about?

NCT03928236 is a clinical study titled "Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium". B-FREE is a pragmatic, multicentre, cluster crossover trial evaluating whether a policy limiting the use of intra-operative benzodiazepine reduces post-operative delirium when compared with a policy of 'ad libitum' administration. The knowledge generated by this study will provide the basis for card...

What is the current status of trial NCT03928236?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 15,886 participants. The study started on 2019-11-18. Estimated completion is 2025-04-30.

What conditions does trial NCT03928236 study?

This clinical trial studies the following conditions: Delirium, Post-cardiac Surgery.

What interventions are being tested in trial NCT03928236?

The interventions under investigation include: Limited Intraoperative Benzodiazepine (OTHER), Liberal Intraoperative Benzodiazepine (OTHER).

Who is sponsoring clinical trial NCT03928236?

This trial is sponsored by Population Health Research Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03928236 being conducted?

This trial has 20 study locations across Missouri, New York, Alberta, British Columbia, Manitoba. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.