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NCT03928236 · ClinicalTrials.gov registry record · NA
Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium
A NA study of Delirium and Post-cardiac Surgery, sponsored by Population Health Research Institute.
- Active
- Registry status
- NA
- Development phase
- 15,886
- Enrollment target
- 20
- Study locations
NCT03928236: Active NA study of Delirium and Post-cardiac Surgery, sponsored by Population Health Research Institute.
NCT03928236 is a NA study of Delirium and Post-cardiac Surgery that is active but no longer recruiting, run by Population Health Research Institute. The registered enrollment target is 15,886 participants, above the 631-participant average among 62 other Delirium trials with a reported enrollment target (2418% higher). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03928236, a NA study of Delirium and Post-cardiac Surgery, is active but no longer recruiting, sponsored by Population Health Research Institute.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 15,886 participants
- Enrollment target
- 20
- Study locations
Study Summary
B-FREE is a pragmatic, multicentre, cluster crossover trial evaluating whether a policy limiting the use of intra-operative benzodiazepine reduces post-operative delirium when compared with a policy of 'ad libitum' administration. The knowledge generated by this study will provide the basis for cardiac anesthesia practice guidelines.
Primary Outcome
Delirium assessed up to 72 hours after surgery using standardized and validated delirium scales
Conditions Studied
Interventions
- OTHER Limited Intraoperative Benzodiazepine
- OTHER Liberal Intraoperative Benzodiazepine
Study Locations (20)
Ontario
- Hamilton Health Sciences, Hamilton General Hospital - Hamilton
- Kingston General Hospital - Kingston
- London Health Sciences Centre - London
- Sunnybrook Health Sciences Centre - Toronto
- St. Michael's Hospital - Toronto
- Toronto General Hospital - Toronto
Quebec
- Montreal Heart Institute - Montreal
- Jewish General Hospital - Montreal
- Hôpital Laval - Québec
- Centre Hospitalier Universitaire de Sherbrooke - Sherbrooke
British Columbia
- Royal Columbian Hospital - New Westminster
- Vancouver General Hospital - Vancouver
- St. Paul's Hospital - Vancouver
Saskatchewan
- Regina General Hospital - Regina
- Royal University Hospital - Saskatoon
Missouri
- Washington University School of Medicine - St Louis
New York
- Weill Cornell Medicine - New York
Alberta
- Mazankowski Alberta Heart Institute - Edmonton
Manitoba
- St. Boniface General Hospital - Winnipeg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15,886 participants |
| Start Date | 2019-11-18 |
| Est. Completion | 2025-04-30 |
| Phase | NA |
What the registry record for NCT03928236 still lists
NCT03928236 is an interventional study that assigns participants to a tested intervention. Its 15,886 participants enrollment target places it among the larger protocols in the corpus, above the 631-participant average among 62 other Delirium trials with a reported enrollment target (2418% higher).
The record links to 2 conditions, with Delirium appearing as the primary indexed condition, and to 2 interventions - of which Limited Intraoperative Benzodiazepine is the first listed.
NCT03928236 names 20 study sites across 9 states, led by Ontario, Quebec, British Columbia.
Frequently Asked Questions
What is clinical trial NCT03928236 about?
NCT03928236 is a clinical study titled "Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium". B-FREE is a pragmatic, multicentre, cluster crossover trial evaluating whether a policy limiting the use of intra-operative benzodiazepine reduces post-operative delirium when compared with a policy of 'ad libitum' administration. The knowledge generated by this study will provide the basis for card...
What is the current status of trial NCT03928236?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 15,886 participants. The study started on 2019-11-18. Estimated completion is 2025-04-30.
What conditions does trial NCT03928236 study?
This clinical trial studies the following conditions: Delirium, Post-cardiac Surgery.
What interventions are being tested in trial NCT03928236?
The interventions under investigation include: Limited Intraoperative Benzodiazepine (OTHER), Liberal Intraoperative Benzodiazepine (OTHER).
Who is sponsoring clinical trial NCT03928236?
This trial is sponsored by Population Health Research Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03928236 being conducted?
This trial has 20 study locations across Missouri, New York, Alberta, British Columbia, Manitoba. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03928236's enrollment target sits among peer trials
15,886 1st of 62 higher than 62 of 62 other Delirium trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Delirium trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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