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NCT05307003 · ClinicalTrials.gov registry record
Trazodone vs. Quetiapine for the Treatment of ICU Delirium
A clinical trial of Delirium and Delirium in Old Age, sponsored by University of Southern California.
- Recruiting
- Registry status
- 60
- Enrollment target
- 1
- Study location
NCT05307003 is a study of Delirium and Delirium in Old Age that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 60 participants, below the 887-participant average among 62 other Delirium trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05307003, a study of Delirium and Delirium in Old Age, is actively recruiting participants, sponsored by University of Southern California.
- RECRUITING
- Registry status
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single-center, prospective observational pilot study. The objective of this study is to evaluate the effectiveness of trazodone as compared to quetiapine, in the management of ICU delirium in adult (\>=18 years old) surgical and medical ICU patients. The investigators will compare outcomes such as delirium duration, delirium-free days, coma-free days, in-hospital mortality, 28-day mortality, hospital length of stay (LOS), ICU LOS, mechanical ventilator days, complications, adverse effects, rescue medication use, delirium symptom severity, sleep duration, and sleep quality among participants receiving trazodone or quetiapine. The investigators hypothesize participants receiving trazodone will be associated with a shorter duration of delirium, decreased delirium severity, and improved sleep quality compared to participants receiving quetiapine.
Conditions Studied
Interventions
- DRUG Trazodone
- DRUG Quetiapine
Study Locations (1)
California
- Keck Hospital of the University of Southern California - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2025-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05307003
The ClinicalTrials.gov registry entry for NCT05307003 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 887-participant average among 62 other Delirium trials with a reported enrollment target (93% lower). The listed sponsor is University of Southern California, which has 617 total studies on file at ClinicalTrials.gov.
The record links to 8 conditions, with Delirium appearing as the primary indexed condition, and to 2 interventions - of which Trazodone is the first listed.
NCT05307003 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05307003 about?
NCT05307003 is a clinical study titled "Trazodone vs. Quetiapine for the Treatment of ICU Delirium". This is a single-center, prospective observational pilot study. The objective of this study is to evaluate the effectiveness of trazodone as compared to quetiapine, in the management of ICU delirium in adult (\>=18 years old) surgical and medical ICU patients. The investigators will compare outcomes...
What is the current status of trial NCT05307003?
This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2023-04-01. Estimated completion is 2025-12.
What conditions does trial NCT05307003 study?
This clinical trial studies the following conditions: Delirium, Delirium in Old Age, Morality, Treatment Side Effects, Delirium, Sepsis Associated.
What interventions are being tested in trial NCT05307003?
The interventions under investigation include: Trazodone (DRUG), Quetiapine (DRUG).
Who is sponsoring clinical trial NCT05307003?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05307003 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.